Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Receptor found that guides nerve cells to their final connecting sites

20.03.2003


In the developing brain, nerve cells make connections with one another by extending processes, often over long distances.



The growing tips of these nerve cell processes are guided to their ultimate connection sites by molecular cues in the environment.

A Salk Institute research team has discovered a receptor-protein interaction that guides nerve cells along specific pathways.


John Thomas, professor of molecular neurobiology, working on the fruit fly Drosophila, found that a protein called Wnt5, a member of a large family of signaling molecules, binds to a receptor called Derailed present on the surface of growing nerve cells.

This binding guides the tips of these nerve cells to their final destination by preventing them from entering the wrong pathway.

This mechanism appears especially important for nerve cells that extend processes across the midline to make connections on the opposite side of the nervous system, a prominent class of nerve cells also found in vertebrates.

This research could have implications for understanding birth defects as well as the regeneration of nerve cells. The study is published in the March 17 edition of Nature

Robert Bradford | EurekAlert!
Further information:
http://www.salk.edu/

More articles from Life Sciences:

nachricht Multifunctional Platform for the Delivery of Gene Therapeutics
22.01.2018 | Angewandte Chemie International Edition

nachricht Charge Order and Electron Localization in a Molecule-Based Solid
22.01.2018 | Max-Planck-Institut für Chemische Physik fester Stoffe

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Artificial agent designs quantum experiments

On the way to an intelligent laboratory, physicists from Innsbruck and Vienna present an artificial agent that autonomously designs quantum experiments. In initial experiments, the system has independently (re)discovered experimental techniques that are nowadays standard in modern quantum optical laboratories. This shows how machines could play a more creative role in research in the future.

We carry smartphones in our pockets, the streets are dotted with semi-autonomous cars, but in the research laboratory experiments are still being designed by...

Im Focus: Scientists decipher key principle behind reaction of metalloenzymes

So-called pre-distorted states accelerate photochemical reactions too

What enables electrons to be transferred swiftly, for example during photosynthesis? An interdisciplinary team of researchers has worked out the details of how...

Im Focus: The first precise measurement of a single molecule's effective charge

For the first time, scientists have precisely measured the effective electrical charge of a single molecule in solution. This fundamental insight of an SNSF Professor could also pave the way for future medical diagnostics.

Electrical charge is one of the key properties that allows molecules to interact. Life itself depends on this phenomenon: many biological processes involve...

Im Focus: Paradigm shift in Paris: Encouraging an holistic view of laser machining

At the JEC World Composite Show in Paris in March 2018, the Fraunhofer Institute for Laser Technology ILT will be focusing on the latest trends and innovations in laser machining of composites. Among other things, researchers at the booth shared with the Aachen Center for Integrative Lightweight Production (AZL) will demonstrate how lasers can be used for joining, structuring, cutting and drilling composite materials.

No other industry has attracted as much public attention to composite materials as the automotive industry, which along with the aerospace industry is a driver...

Im Focus: Room-temperature multiferroic thin films and their properties

Scientists at Tokyo Institute of Technology (Tokyo Tech) and Tohoku University have developed high-quality GFO epitaxial films and systematically investigated their ferroelectric and ferromagnetic properties. They also demonstrated the room-temperature magnetocapacitance effects of these GFO thin films.

Multiferroic materials show magnetically driven ferroelectricity. They are attracting increasing attention because of their fascinating properties such as...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

10th International Symposium: “Advanced Battery Power – Kraftwerk Batterie” Münster, 10-11 April 2018

08.01.2018 | Event News

See, understand and experience the work of the future

11.12.2017 | Event News

Innovative strategies to tackle parasitic worms

08.12.2017 | Event News

 
Latest News

Multifunctional Platform for the Delivery of Gene Therapeutics

22.01.2018 | Life Sciences

The world's most powerful acoustic tractor beam could pave the way for levitating humans

22.01.2018 | Power and Electrical Engineering

Siberian scientists learned how to reduce harmful emissions from HPPs

22.01.2018 | Power and Electrical Engineering

VideoLinks
B2B-VideoLinks
More VideoLinks >>>