Researchers in Oxford University’s Department of Inorganic Chemistry have devised a method for the selective separation and recovery of nucleoside phosphates from complex reaction mixtures using Layered Double Hydroxide (LDH) materials.
Nucleoside phosphates are used extensively in industry as intermediates or additives in nutraceutical and pharmaceutical preparation, as well as in medical and separation science. In particular many new antiviral agents are based on nucleosides. Supplying the potential demand for nucleoside phosphates poses a challenge to current technological approaches. Therefore, simple purification processes for the recovery of large quantities of valuable nucleoside phosphates contained within mixtures of other nucleoside phosphates is needed.
In the new Oxford method, LDH materials are used as fast, efficient and high capacity ion exchange materials for the removal of organic and inorganic anions from aqueous streams because they have the capacity to form intercalation compounds with the desired anions. The majority of LDHs are made from anionic clays or clay mineral materials. Following the intercalation step, the desired nucleoside phosphate compounds are removed from within the LDH material by simple chemical means to leave the LDH material intact and ready for re-use. The main competitive advantages of this method lie within the high purity of the resultant nucleoside phosphates, the ease of scale up and the fewer number of process steps. Additionally, the LDH material is designed for use with conventional filtration technologies.
Jennifer Johnson | alfa
New application for acoustics helps estimate marine life populations
16.01.2018 | University of California - San Diego
Unexpected environmental source of methane discovered
16.01.2018 | University of Washington Health Sciences/UW Medicine
What enables electrons to be transferred swiftly, for example during photosynthesis? An interdisciplinary team of researchers has worked out the details of how...
For the first time, scientists have precisely measured the effective electrical charge of a single molecule in solution. This fundamental insight of an SNSF Professor could also pave the way for future medical diagnostics.
Electrical charge is one of the key properties that allows molecules to interact. Life itself depends on this phenomenon: many biological processes involve...
At the JEC World Composite Show in Paris in March 2018, the Fraunhofer Institute for Laser Technology ILT will be focusing on the latest trends and innovations in laser machining of composites. Among other things, researchers at the booth shared with the Aachen Center for Integrative Lightweight Production (AZL) will demonstrate how lasers can be used for joining, structuring, cutting and drilling composite materials.
No other industry has attracted as much public attention to composite materials as the automotive industry, which along with the aerospace industry is a driver...
Scientists at Tokyo Institute of Technology (Tokyo Tech) and Tohoku University have developed high-quality GFO epitaxial films and systematically investigated their ferroelectric and ferromagnetic properties. They also demonstrated the room-temperature magnetocapacitance effects of these GFO thin films.
Multiferroic materials show magnetically driven ferroelectricity. They are attracting increasing attention because of their fascinating properties such as...
The oceans are the largest global heat reservoir. As a result of man-made global warming, the temperature in the global climate system increases; around 90% of...
08.01.2018 | Event News
11.12.2017 | Event News
08.12.2017 | Event News
16.01.2018 | Materials Sciences
16.01.2018 | Materials Sciences
16.01.2018 | Power and Electrical Engineering