A research team at two Midwest universities has developed a new way to genetically alter cells in living mice, offering new possibilities in the war against cancer and other diseases.
Using a modified virus as a Trojan horse, a team led by Purdue Universitys David Sanders has found a promising system to deliver genes to diseased liver and brain cells. By placing helpful genetic material within the outer protein shell of Ross River Virus (RRV), Sanders team was able to alter the mices liver cells without producing the harmful side effects that have accompanied the use of other retroviruses.
"This represents a major advance in that we have used retroviruses for gene therapy, not just in tissue samples, but in living mice," said Sanders, associate professor of biological sciences at Purdue. "This brings us a giant step closer to treating human diseases."
Chad Boutin | EurekAlert!
At last, butterflies get a bigger, better evolutionary tree
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Scientists from the University of Zurich have succeeded for the first time in tracking individual stem cells and their neuronal progeny over months within the intact adult brain. This study sheds light on how new neurons are produced throughout life.
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Let’s say the armrest is broken in your vintage car. As things stand, you would need a lot of luck and persistence to find the right spare part. But in the world of Industrie 4.0 and production with batch sizes of one, you can simply scan the armrest and print it out. This is made possible by the first ever 3D scanner capable of working autonomously and in real time. The autonomous scanning system will be on display at the Hannover Messe Preview on February 6 and at the Hannover Messe proper from April 23 to 27, 2018 (Hall 6, Booth A30).
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