Bacteria that reproduce inside aphids have not changed their genetic make-up for the last 50-70 million years. This makes the genomes of these bacteria the most stable of all organisms yet studied. This finding is presented by a team of scientists at Uppsala University, Sweden, in the latest issue of the scientific journal Science.
Under the leadership of Professor Siv Andersson, researchers Ivica Tama, Lisa Klasson, Björn Canbäck, Kristina Näslund, Ann-Sofie Eriksson, and Johan Sandström at the Department of Molecular Evolution, Center for Evolutionary Biology, in collaboration with Professor Nancy Moran in Tucson, Arizona, have described the entire genetic make-up of a bacterium that reproduces inside aphids, Buchnera (Sg) and compared it to that of a close relative, Buchnera (Ap).
These aphid endosymbionts, so called because they live in symbiosis with aphids, are closely related to common bacteria like Salmonella, but the adaptation to the aphids have entailed a drastic reduction in the size of the genome, which now consists of only 640,000 bases, about 14% of the genome of Salmonella species.
Jon Hogdal | alfa
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Staphylococcus aureus is a feared pathogen (MRSA, multi-resistant S. aureus) due to frequent resistances against many antibiotics, especially in hospital infections. Researchers at the Paul-Ehrlich-Institut have identified immunological processes that prevent a successful immune response directed against the pathogenic agent. The delivery of bacterial proteins with RNA adjuvant or messenger RNA (mRNA) into immune cells allows the re-direction of the immune response towards an active defense against S. aureus. This could be of significant importance for the development of an effective vaccine. PLOS Pathogens has published these research results online on 25 May 2017.
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26.05.2017 | Life Sciences
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