Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

First-class protein crystals thanks to weightlessness on earth

24.04.2008
Dutch chemist Paul Poodt has developed two attractive alternatives for allowing protein crystals to grow under weightless conditions.

If the crystals are grown upside down in a strong magnetic field, fluid flows that disrupt crystal growth are suppressed. Therefore, high-quality proteins no longer need to be grown in space, but can be grown here on earth.

Protein crystals provide vital knowledge for drug development. The production of an effective drug requires knowledge of how biomolecules such as body proteins are constructed. If you want to know how proteins work, you must first of all determine their molecular structure using X-ray diffraction.

This requires exceptionally high-quality protein crystals. However, allowing these to grow can be extremely difficult and sometimes even impossible: the presence of gravity gives rise to fluid flows in the crystal solution, which, in turn, disrupt the growth process. Undisturbed growth yields the finest crystals.

... more about:
»Earth »Fluid »Protein »weightlessness
Space crystals
In order to prevent fluid flows, the decision is often taken to grow the protein crystals in space on. However, as this is a very expensive and time-consuming undertaking, scientists are looking for methods to create weightlessness on earth. The experiment in Nijmegen is the first in the world to demonstrate that a crystal can grow uniformly in a strong magnetic field.

Paul Poodt (Zevenaar, 1979) studied physical chemistry. His PhD research - supported by the Open Competition of NWO Chemical Sciences - is part of the programme of the Institute for Molecules and Material (IMM) of the Radboud University Nijmegen.

Sonja Knols | alfa
Further information:
http://www.nwo.nl/nwohome.nsf/pages/NWOA_7DPBTL_Eng

Further reports about: Earth Fluid Protein weightlessness

More articles from Life Sciences:

nachricht MicroRNA helps cancer evade immune system
19.09.2017 | Salk Institute

nachricht Ruby: Jacobs University scientists are collaborating in the development of a new type of chocolate
18.09.2017 | Jacobs University Bremen gGmbH

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Ultrafast snapshots of relaxing electrons in solids

Using ultrafast flashes of laser and x-ray radiation, scientists at the Max Planck Institute of Quantum Optics (Garching, Germany) took snapshots of the briefest electron motion inside a solid material to date. The electron motion lasted only 750 billionths of the billionth of a second before it fainted, setting a new record of human capability to capture ultrafast processes inside solids!

When x-rays shine onto solid materials or large molecules, an electron is pushed away from its original place near the nucleus of the atom, leaving a hole...

Im Focus: Quantum Sensors Decipher Magnetic Ordering in a New Semiconducting Material

For the first time, physicists have successfully imaged spiral magnetic ordering in a multiferroic material. These materials are considered highly promising candidates for future data storage media. The researchers were able to prove their findings using unique quantum sensors that were developed at Basel University and that can analyze electromagnetic fields on the nanometer scale. The results – obtained by scientists from the University of Basel’s Department of Physics, the Swiss Nanoscience Institute, the University of Montpellier and several laboratories from University Paris-Saclay – were recently published in the journal Nature.

Multiferroics are materials that simultaneously react to electric and magnetic fields. These two properties are rarely found together, and their combined...

Im Focus: Fast, convenient & standardized: New lab innovation for automated tissue engineering & drug

MBM ScienceBridge GmbH successfully negotiated a license agreement between University Medical Center Göttingen (UMG) and the biotech company Tissue Systems Holding GmbH about commercial use of a multi-well tissue plate for automated and reliable tissue engineering & drug testing.

MBM ScienceBridge GmbH successfully negotiated a license agreement between University Medical Center Göttingen (UMG) and the biotech company Tissue Systems...

Im Focus: Silencing bacteria

HZI researchers pave the way for new agents that render hospital pathogens mute

Pathogenic bacteria are becoming resistant to common antibiotics to an ever increasing degree. One of the most difficult germs is Pseudomonas aeruginosa, a...

Im Focus: Artificial Enzymes for Hydrogen Conversion

Scientists from the MPI for Chemical Energy Conversion report in the first issue of the new journal JOULE.

Cell Press has just released the first issue of Joule, a new journal dedicated to sustainable energy research. In this issue James Birrell, Olaf Rüdiger,...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

“Lasers in Composites Symposium” in Aachen – from Science to Application

19.09.2017 | Event News

I-ESA 2018 – Call for Papers

12.09.2017 | Event News

EMBO at Basel Life, a new conference on current and emerging life science research

06.09.2017 | Event News

 
Latest News

“Lasers in Composites Symposium” in Aachen – from Science to Application

19.09.2017 | Event News

New quantum phenomena in graphene superlattices

19.09.2017 | Physics and Astronomy

A simple additive to improve film quality

19.09.2017 | Power and Electrical Engineering

VideoLinks
B2B-VideoLinks
More VideoLinks >>>