Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Wildebeest or malaria parasite - same rules determine number of offspring

15.01.2008
Whether you are dealing with the number of wildebeest on the Serengeti or the number of malaria parasites in the human body, new research shows the same ecological framework determines breeding numbers and population size.

New research published today (15 January) in Proceedings of the National Academy of Sciences by a Biotechnology and Biological Sciences Research Council (BBSRC) Fellow shows that the same community ecology principles that determine how different animal species on the savannah affect each other's population sizes through competition for food and hunting by predators also affect parasite species interacting within the microcosm of a single host.

The research has important implications for treating many human and animal infections, including malaria and viruses. These infections rarely occur singularly and the research at the University of Edinburgh suggests that a range of drugs used to treat infection by parasitic worms may alter the effectiveness of anti-malarial and anti-viral treatments by affecting the level of competition among parasite species.

The research, conducted by Dr Andrea Graham, a BBSRC David Phillips Fellow at the University of Edinburgh, examined data from a large number of animal studies of coinfection. A microparasite infection such as malaria often occurs in people already suffering from other parasites, such as worms. The research shows that these multiple infections affect each other by competing for host nutrients or by generating an impaired immune system response. The effect is the same as if a large herd of wildebeest started to eat all the available food in an area of the Serengeti. Analogously, the study found that if a host was suffering from a worm infection that caused a reduction in a nutrient needed by another parasite in the body at the same time, the second parasite would be reduced in number. Conversely, if a worm infection suppressed the immune response, other parasites would explode in numbers, just as zebras would rapidly breed in the absence of lions.

... more about:
»Host »Malaria »determine »treat

Dr Graham said: "People and animals do not normally suffer just one parasite infection at a time. By applying the same ideas used in studies of big ecosystems to parasites I have been able to show that we need ecological thinking in order to understand and thus control multiple infections. This approach will help us to most effectively treat diseases such as malaria in a world that's full of co-infected hosts.

"Researchers have mostly studied and treated viral and bacterial infections in isolation. This is because multiple-species infections were previously thought to be far too complex to be understood. Now I've shown that we need to think like ecologists to make the problem more controllable."

Professor Nigel Brown, BBSRC Directory of Science and Technology, said: "This research focuses on understanding the fundamental biology of parasite infections but has huge practical implications. Ecological principles are here shown to have huge potential in understanding and treating parasitic disease, and shows the importance of interdisciplinary thinking in science and medicine."

Matt Goode | alfa
Further information:
http://www.bbsrc.ac.uk

Further reports about: Host Malaria determine treat

More articles from Life Sciences:

nachricht Discovery of a Key Regulatory Gene in Cardiac Valve Formation
24.05.2017 | Universität Basel

nachricht Carcinogenic soot particles from GDI engines
24.05.2017 | Empa - Eidgenössische Materialprüfungs- und Forschungsanstalt

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: A quantum walk of photons

Physicists from the University of Würzburg are capable of generating identical looking single light particles at the push of a button. Two new studies now demonstrate the potential this method holds.

The quantum computer has fuelled the imagination of scientists for decades: It is based on fundamentally different phenomena than a conventional computer....

Im Focus: Turmoil in sluggish electrons’ existence

An international team of physicists has monitored the scattering behaviour of electrons in a non-conducting material in real-time. Their insights could be beneficial for radiotherapy.

We can refer to electrons in non-conducting materials as ‘sluggish’. Typically, they remain fixed in a location, deep inside an atomic composite. It is hence...

Im Focus: Wafer-thin Magnetic Materials Developed for Future Quantum Technologies

Two-dimensional magnetic structures are regarded as a promising material for new types of data storage, since the magnetic properties of individual molecular building blocks can be investigated and modified. For the first time, researchers have now produced a wafer-thin ferrimagnet, in which molecules with different magnetic centers arrange themselves on a gold surface to form a checkerboard pattern. Scientists at the Swiss Nanoscience Institute at the University of Basel and the Paul Scherrer Institute published their findings in the journal Nature Communications.

Ferrimagnets are composed of two centers which are magnetized at different strengths and point in opposing directions. Two-dimensional, quasi-flat ferrimagnets...

Im Focus: World's thinnest hologram paves path to new 3-D world

Nano-hologram paves way for integration of 3-D holography into everyday electronics

An Australian-Chinese research team has created the world's thinnest hologram, paving the way towards the integration of 3D holography into everyday...

Im Focus: Using graphene to create quantum bits

In the race to produce a quantum computer, a number of projects are seeking a way to create quantum bits -- or qubits -- that are stable, meaning they are not much affected by changes in their environment. This normally needs highly nonlinear non-dissipative elements capable of functioning at very low temperatures.

In pursuit of this goal, researchers at EPFL's Laboratory of Photonics and Quantum Measurements LPQM (STI/SB), have investigated a nonlinear graphene-based...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Marine Conservation: IASS Contributes to UN Ocean Conference in New York on 5-9 June

24.05.2017 | Event News

AWK Aachen Machine Tool Colloquium 2017: Internet of Production for Agile Enterprises

23.05.2017 | Event News

Dortmund MST Conference presents Individualized Healthcare Solutions with micro and nanotechnology

22.05.2017 | Event News

 
Latest News

Physicists discover mechanism behind granular capillary effect

24.05.2017 | Physics and Astronomy

Measured for the first time: Direction of light waves changed by quantum effect

24.05.2017 | Physics and Astronomy

Marine Conservation: IASS Contributes to UN Ocean Conference in New York on 5-9 June

24.05.2017 | Event News

VideoLinks
B2B-VideoLinks
More VideoLinks >>>