The large EU project PROSPECTS is a collaborative research effort of leading European scientists in the Proteomics field. PROSPECTS now presents a number of breakthroughs in a series of articles comprising a "Special Issue" of the top journal of the field: Molecular & Cellular Proteomics.
Coordinated by Matthias Mann, director at the Max Planck Institute of Biochemistry (MPIB) in Martinsried near Munich, Germany, the scientists lay out their contribution to the future of proteomics with a powerful and versatile set of assay systems for characterizing proteome dynamics.
“Proteomics specification in time and space” (PROSPECTS) is a five year collaborative project that commenced early in 2008 and is funded by the Research Directorate of the European Commission under the 7th Research Framework Program. PROSPECTS brings together ten leading research groups from around Europe, as well as Thermo Fisher Scientific, a mass spectrometry instrument manufacturer and chromatography company.
The different groups seek new insights into the cellular function of proteins and their aberration during diseases. “We here present a perspective on how the proteomics field is moving beyond simply identifying proteins,” says Matthias Mann. “It now provides powerful tools for characterizing proteome dynamics and thereby creates a new level of proteomics research.” The "Special Issue" contains a series of 16 original research papers documenting the recent progress in all aspects of proteomic research achieved within PROSPECTS.Original publications
Anja Konschak | Max-Planck-Institut
Rochester scientists discover gene controlling genetic recombination rates
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One step closer to reality
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Stable joint cartilage can be produced from adult stem cells originating from bone marrow. This is made possible by inducing specific molecular processes occurring during embryonic cartilage formation, as researchers from the University and University Hospital of Basel report in the scientific journal PNAS.
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In the fight against cancer, scientists are developing new drugs to hit tumor cells at so far unused weak points. Such a “sore spot” is the protein complex...
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