The studies, which are published in Nature Genetics, show amongst other things, that hair follicle stem cells can divide actively and transport themselves through the skin tissue.
"The stem cells don't behave at all in the way we'd previously thought, and are found in unexpected places," says Professor Rune Toftgård, one of the scientists at Karolinska Institutet responsible for the study. "We're now investigating the part played by the stem cells in the wound-healing process and the development of basal cell carcinoma, the most common form of skin cancer."
The stem cells examined by the present study are found in the skin's hair follicles, around which the cells are able to move depending on their stage of growth. The scientists believe that their growth is governed by previously known mechanism called Hedgehog signalling. Mutations in the genes that control this signal system can cause the delayed deactivation of signal transference; the signals thus continue uninhibited, which increases the risk of cancer.
Publication: "Lgr5marks cycling, yet long-lived, hair follicle stem cells", Viljar Jaks, Nick Barker, Maria Kasper, Johan H van Es, Hugo J Snippert, Hans Clevers, Rune Toftgård, Nature Genetics, AOP 12 October 2008, doi 10.1038/ng.239.
For further information, please contact:Professor Rune Toftgård
Newly discovered bacteria-binding protein in the intestine
08.12.2016 | University of Gothenburg
The balancing act: An enzyme that links endocytosis to membrane recycling
07.12.2016 | National Centre for Biological Sciences
In recent years, lasers with ultrashort pulses (USP) down to the femtosecond range have become established on an industrial scale. They could advance some applications with the much-lauded “cold ablation” – if that meant they would then achieve more throughput. A new generation of process engineering that will address this issue in particular will be discussed at the “4th UKP Workshop – Ultrafast Laser Technology” in April 2017.
Even back in the 1990s, scientists were comparing materials processing with nanosecond, picosecond and femtosesecond pulses. The result was surprising:...
Have you ever wondered how you see the world? Vision is about photons of light, which are packets of energy, interacting with the atoms or molecules in what...
A multi-institutional research collaboration has created a novel approach for fabricating three-dimensional micro-optics through the shape-defined formation of porous silicon (PSi), with broad impacts in integrated optoelectronics, imaging, and photovoltaics.
Working with colleagues at Stanford and The Dow Chemical Company, researchers at the University of Illinois at Urbana-Champaign fabricated 3-D birefringent...
In experiments with magnetic atoms conducted at extremely low temperatures, scientists have demonstrated a unique phase of matter: The atoms form a new type of quantum liquid or quantum droplet state. These so called quantum droplets may preserve their form in absence of external confinement because of quantum effects. The joint team of experimental physicists from Innsbruck and theoretical physicists from Hannover report on their findings in the journal Physical Review X.
“Our Quantum droplets are in the gas phase but they still drop like a rock,” explains experimental physicist Francesca Ferlaino when talking about the...
The Max Planck Institute for Physics (MPP) is opening up a new research field. A workshop from November 21 - 22, 2016 will mark the start of activities for an innovative axion experiment. Axions are still only purely hypothetical particles. Their detection could solve two fundamental problems in particle physics: What dark matter consists of and why it has not yet been possible to directly observe a CP violation for the strong interaction.
The “MADMAX” project is the MPP’s commitment to axion research. Axions are so far only a theoretical prediction and are difficult to detect: on the one hand,...
16.11.2016 | Event News
01.11.2016 | Event News
14.10.2016 | Event News
08.12.2016 | Physics and Astronomy
08.12.2016 | Health and Medicine
08.12.2016 | Life Sciences