The chloroplast proteins cpSRP43 and cpSRP54 function in this chaperone role for the light-harvesting proteins. “Deciphering the three-dimensional structure of the core complex of these two proteins allows us to draw basic conclusions about how the chaperone functions”, explains Prof. Dr. Irm¬gard Sinning of the Heidelberg University Biochemistry Center (BZH). The team of scientists working with Prof. Sinning discovered that two protein motifs take part in the interaction between cpSRP43 and cpSRP54, similar to the motifs that play a central role in regulating access to the genetic material in the cell nucleus. While scientists have known for years about the “histone code” involved in the processes in the nucleus, they now face the puzzle of the newly discovered “arginine code” in the chloroplasts.The Heidelberg scientists conducted their research in close cooperation with colleagues from the Munich Technical University and the European Synchrotron Radiation Facility (ESRF) in Grenoble (France). The researchers combined different structural biology methods in the pursuit of their work. X-ray structure analysis, nuclear magnetic resonance (NMR) spectroscopy, and small angle X-ray scattering were key in revealing the architecture and dynamics of the core complex of cpSRP43 und cpSRP54. In addition, they took advantage of the Biochemistry Center’s protein crystallization platform, which receives support from the Cluster of Excellence CellNetworks at Heidelberg University. The results of the research were published in “Nature Structural & Molecular Biology”.
Marietta Fuhrmann-Koch | idw
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Satellites in near-Earth orbit are at risk due to the steady increase in space debris. But their mission in the areas of telecommunications, navigation or weather forecasts is essential for society. Fraunhofer FHR therefore develops radar-based systems which allow the detection, tracking and cataloging of even the smallest particles of debris. Satellite operators who have access to our data are in a better position to plan evasive maneuvers and prevent destructive collisions. From April, 25-29 2018, Fraunhofer FHR and its partners will exhibit the complementary radar systems TIRA and GESTRA as well as the latest radar techniques for space observation across three stands at the ILA Berlin.
The "traffic situation" in space is very tense: the Earth is currently being orbited not only by countless satellites but also by a large volume of space...
An international team of researchers has discovered a new anti-cancer protein. The protein, called LHPP, prevents the uncontrolled proliferation of cancer cells in the liver. The researchers led by Prof. Michael N. Hall from the Biozentrum, University of Basel, report in “Nature” that LHPP can also serve as a biomarker for the diagnosis and prognosis of liver cancer.
The incidence of liver cancer, also known as hepatocellular carcinoma, is steadily increasing. In the last twenty years, the number of cases has almost doubled...
In just a few weeks from now, the Chinese space station Tiangong-1 will re-enter the Earth's atmosphere where it will to a large extent burn up. It is possible that some debris will reach the Earth's surface. Tiangong-1 is orbiting the Earth uncontrolled at a speed of approx. 29,000 km/h.Currently the prognosis relating to the time of impact currently lies within a window of several days. The scientists at Fraunhofer FHR have already been monitoring Tiangong-1 for a number of weeks with their TIRA system, one of the most powerful space observation radars in the world, with a view to supporting the German Space Situational Awareness Center and the ESA with their re-entry forecasts.
Following the loss of radio contact with Tiangong-1 in 2016 and due to the low orbital height, it is now inevitable that the Chinese space station will...
Fraunhofer Institute for Organic Electronics, Electron Beam and Plasma Technology FEP, provider of research and development services for OLED lighting solutions, announces the founding of the “OLED Licht Forum” and presents latest OLED design and lighting solutions during light+building, from March 18th – 23rd, 2018 in Frankfurt a.M./Germany, at booth no. F91 in Hall 4.0.
They are united in their passion for OLED (organic light emitting diodes) lighting with all of its unique facets and application possibilities. Thus experts in...
A new scenario seeking to explain how Mars' putative oceans came and went over the last 4 billion years implies that the oceans formed several hundred million...
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