The findings of the UK College of Agriculture researchers, led by Pradeep Kachroo and Aardra Kachroo, were published online in Nature Genetics March 27. Researchers from the UK Department of Statistics and Washington State University also contributed to the article.
"If you can generate systemic immunity, you can have great benefits in disease resistance," Pradeep Kachroo said. "It is particularly gratifying to be able to describe a mechanism for a type of immunity; pioneering studies were incidentally carried out by our own emeritus faculty, Joe Kuc."
Using soybeans and Arabidopsis, a model laboratory plant, the scientists were able to identify the metabolite glycerol-3-phosphate as a key mobile regulator of systemic immunity. A metabolite is a substance produced in the body through normal metabolic processes. The glycerol-3-phosphate transforms into an unknown compound and uses a protein, called DIR1 to signal systemic immunity. Scientists already identified the protein as a necessary component to trigger systemic immunity.
"The metabolite and protein are dependent on each other to transport immunity from one location in the plant tissue to the other," Pradeep Kachroo said. "Metabolite levels increase in plant tissues after the plant has been inoculated by a pathogen."
While the research was conducted on plants, Pradeep Kachroo said all organisms have a similar process of triggering systemic immunity.
"The metabolite is a highly conserved compound in all species across the board," Pradeep Kachroo said. "Another great thing is increased levels of this metabolite do not affect plant productivity, unlike other known inducers of systemic immunity."
He said the metabolite could be an effective tool to control plant diseases and enhance pathogen tolerance in plants.
In 2008, these UK plant pathologists discovered that the same metabolite was a key component in organisms' basal resistance, which allows organisms to have strong immune systems. They wondered whether there was a connection between the metabolite and systemic immunity, which led them to their current research.
Their research was funded by the National Science Foundation's Division of Integrative Organismal Systems. The plant pathologists will continue to study the process that induces systemic immunity.
"We want to know how glycerol-3-phosphate is metabolized in plants and identify various compounds derived from glycerol-3-phosphate," Pradeep Kachroo said. "We also want to know how the metabolite relates other molecules known to be important for systemic immunity."
Contact: Pradeep Kachroo, 859-257-7445 or Aardra Kachroo, 859-257-7445, ext. 81292
Katie Pratt | EurekAlert!
Researchers identify potentially druggable mutant p53 proteins that promote cancer growth
09.12.2016 | Cold Spring Harbor Laboratory
Plant-based substance boosts eyelash growth
09.12.2016 | Fraunhofer-Institut für Angewandte Polymerforschung IAP
Physicists of the University of Würzburg have made an astonishing discovery in a specific type of topological insulators. The effect is due to the structure of the materials used. The researchers have now published their work in the journal Science.
Topological insulators are currently the hot topic in physics according to the newspaper Neue Zürcher Zeitung. Only a few weeks ago, their importance was...
In recent years, lasers with ultrashort pulses (USP) down to the femtosecond range have become established on an industrial scale. They could advance some applications with the much-lauded “cold ablation” – if that meant they would then achieve more throughput. A new generation of process engineering that will address this issue in particular will be discussed at the “4th UKP Workshop – Ultrafast Laser Technology” in April 2017.
Even back in the 1990s, scientists were comparing materials processing with nanosecond, picosecond and femtosesecond pulses. The result was surprising:...
Have you ever wondered how you see the world? Vision is about photons of light, which are packets of energy, interacting with the atoms or molecules in what...
A multi-institutional research collaboration has created a novel approach for fabricating three-dimensional micro-optics through the shape-defined formation of porous silicon (PSi), with broad impacts in integrated optoelectronics, imaging, and photovoltaics.
Working with colleagues at Stanford and The Dow Chemical Company, researchers at the University of Illinois at Urbana-Champaign fabricated 3-D birefringent...
In experiments with magnetic atoms conducted at extremely low temperatures, scientists have demonstrated a unique phase of matter: The atoms form a new type of quantum liquid or quantum droplet state. These so called quantum droplets may preserve their form in absence of external confinement because of quantum effects. The joint team of experimental physicists from Innsbruck and theoretical physicists from Hannover report on their findings in the journal Physical Review X.
“Our Quantum droplets are in the gas phase but they still drop like a rock,” explains experimental physicist Francesca Ferlaino when talking about the...
16.11.2016 | Event News
01.11.2016 | Event News
14.10.2016 | Event News
09.12.2016 | Life Sciences
09.12.2016 | Ecology, The Environment and Conservation
09.12.2016 | Health and Medicine