Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Kentucky researchers find a key to plant disease resistance

29.03.2011
University of Kentucky plant pathologists recently discovered a metabolite that plays a critical role early on in the ability of plants, animals, humans and one-celled microorganisms to fend off a wide range of pathogens at the cellular level, which is known as systemic immunity. This mode of resistance has been known for more than 100 years, but the key events that stimulate that resistance have remained a mystery.

The findings of the UK College of Agriculture researchers, led by Pradeep Kachroo and Aardra Kachroo, were published online in Nature Genetics March 27. Researchers from the UK Department of Statistics and Washington State University also contributed to the article.

"If you can generate systemic immunity, you can have great benefits in disease resistance," Pradeep Kachroo said. "It is particularly gratifying to be able to describe a mechanism for a type of immunity; pioneering studies were incidentally carried out by our own emeritus faculty, Joe Kuc."

Using soybeans and Arabidopsis, a model laboratory plant, the scientists were able to identify the metabolite glycerol-3-phosphate as a key mobile regulator of systemic immunity. A metabolite is a substance produced in the body through normal metabolic processes. The glycerol-3-phosphate transforms into an unknown compound and uses a protein, called DIR1 to signal systemic immunity. Scientists already identified the protein as a necessary component to trigger systemic immunity.

"The metabolite and protein are dependent on each other to transport immunity from one location in the plant tissue to the other," Pradeep Kachroo said. "Metabolite levels increase in plant tissues after the plant has been inoculated by a pathogen."

While the research was conducted on plants, Pradeep Kachroo said all organisms have a similar process of triggering systemic immunity.

"The metabolite is a highly conserved compound in all species across the board," Pradeep Kachroo said. "Another great thing is increased levels of this metabolite do not affect plant productivity, unlike other known inducers of systemic immunity."

He said the metabolite could be an effective tool to control plant diseases and enhance pathogen tolerance in plants.

In 2008, these UK plant pathologists discovered that the same metabolite was a key component in organisms' basal resistance, which allows organisms to have strong immune systems. They wondered whether there was a connection between the metabolite and systemic immunity, which led them to their current research.

Their research was funded by the National Science Foundation's Division of Integrative Organismal Systems. The plant pathologists will continue to study the process that induces systemic immunity.

"We want to know how glycerol-3-phosphate is metabolized in plants and identify various compounds derived from glycerol-3-phosphate," Pradeep Kachroo said. "We also want to know how the metabolite relates other molecules known to be important for systemic immunity."

Contact: Pradeep Kachroo, 859-257-7445 or Aardra Kachroo, 859-257-7445, ext. 81292

Katie Pratt | EurekAlert!
Further information:
http://www.uky.edu

More articles from Life Sciences:

nachricht Single-stranded DNA and RNA origami go live
15.12.2017 | Wyss Institute for Biologically Inspired Engineering at Harvard

nachricht New antbird species discovered in Peru by LSU ornithologists
15.12.2017 | Louisiana State University

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: First-of-its-kind chemical oscillator offers new level of molecular control

DNA molecules that follow specific instructions could offer more precise molecular control of synthetic chemical systems, a discovery that opens the door for engineers to create molecular machines with new and complex behaviors.

Researchers have created chemical amplifiers and a chemical oscillator using a systematic method that has the potential to embed sophisticated circuit...

Im Focus: Long-lived storage of a photonic qubit for worldwide teleportation

MPQ scientists achieve long storage times for photonic quantum bits which break the lower bound for direct teleportation in a global quantum network.

Concerning the development of quantum memories for the realization of global quantum networks, scientists of the Quantum Dynamics Division led by Professor...

Im Focus: Electromagnetic water cloak eliminates drag and wake

Detailed calculations show water cloaks are feasible with today's technology

Researchers have developed a water cloaking concept based on electromagnetic forces that could eliminate an object's wake, greatly reducing its drag while...

Im Focus: Scientists channel graphene to understand filtration and ion transport into cells

Tiny pores at a cell's entryway act as miniature bouncers, letting in some electrically charged atoms--ions--but blocking others. Operating as exquisitely sensitive filters, these "ion channels" play a critical role in biological functions such as muscle contraction and the firing of brain cells.

To rapidly transport the right ions through the cell membrane, the tiny channels rely on a complex interplay between the ions and surrounding molecules,...

Im Focus: Towards data storage at the single molecule level

The miniaturization of the current technology of storage media is hindered by fundamental limits of quantum mechanics. A new approach consists in using so-called spin-crossover molecules as the smallest possible storage unit. Similar to normal hard drives, these special molecules can save information via their magnetic state. A research team from Kiel University has now managed to successfully place a new class of spin-crossover molecules onto a surface and to improve the molecule’s storage capacity. The storage density of conventional hard drives could therefore theoretically be increased by more than one hundred fold. The study has been published in the scientific journal Nano Letters.

Over the past few years, the building blocks of storage media have gotten ever smaller. But further miniaturization of the current technology is hindered by...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

See, understand and experience the work of the future

11.12.2017 | Event News

Innovative strategies to tackle parasitic worms

08.12.2017 | Event News

AKL’18: The opportunities and challenges of digitalization in the laser industry

07.12.2017 | Event News

 
Latest News

Engineers program tiny robots to move, think like insects

15.12.2017 | Power and Electrical Engineering

One in 5 materials chemistry papers may be wrong, study suggests

15.12.2017 | Materials Sciences

New antbird species discovered in Peru by LSU ornithologists

15.12.2017 | Life Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>