To obtain hydrogen as an energy-rich and environmentally "clean" fuel by an inexpensive, simple method without using expensive metal catalysts preoccupies scientists around the world. Hydrogenases, enzymes employed by organisms to yield hydrogen under anaerobic conditions, are being studied intensively as alternative systems.
A very popular research strategy is to build enzyme models that can then be modified to bring them closer to the ultimate goal of functioning even in the presence of some oxygen and not being impeded, or “poisoned”, by the hydrogen gas produced. Azadithiolate (S−–CH2–NH–CH2–S−) is one of the seven cofactors that make up an important part of such a hydrogenase catalyst.
Thomas Rauchfuss and his team at the University of Illinois at Urbana-Champaign developed a new approach to obtain this cofactor, which is described in the Short Communication published in the European Journal of Inorganic Chemistry.
This new approach employs organotitanium compounds, which are known to enable the synthesis of unusual ligands containing sulfur. A dithiolatotitanocene complex was first synthesized, demonstrating that titanocene stabilizes azadithiolate ligands. The next step was to transfer the azadithiolate ligand from the titanocene to a dinuclear iron center, which was successfully carried out with efficiency and good yield.
The importance of this new route to obtain diiron azadithiolato complexes is that it proceeds with high yield and does not require complicated reagents. In addition to describing the first synthesis and structural characterization of an azadithiolato complex not based on the diiron core, the scientists have succeeded in transferring the azadithiolate ligand to the diiron center, which enables further studies of this important cofactor.
Author: Thomas Rauchfuss, University of Illinois at Urbana-Champaign (USA), http://chemistry.illinois.edu/faculty/Thomas_Rauchfuss.html
Title: A New Route to Azadithiolato Complexes
European Journal of Inorganic Chemistry, Permalink to the article: http://dx.doi.org/10.1002/ejic.201001208
Thomas Rauchfuss | Wiley-VCH
First time-lapse footage of cell activity during limb regeneration
25.10.2016 | eLife
Phenotype at the push of a button
25.10.2016 | Institut für Pflanzenbiochemie
Ultrafast lasers have introduced new possibilities in engraving ultrafine structures, and scientists are now also investigating how to use them to etch microstructures into thin glass. There are possible applications in analytics (lab on a chip) and especially in electronics and the consumer sector, where great interest has been shown.
This new method was born of a surprising phenomenon: irradiating glass in a particular way with an ultrafast laser has the effect of making the glass up to a...
Terahertz excitation of selected crystal vibrations leads to an effective magnetic field that drives coherent spin motion
Controlling functional properties by light is one of the grand goals in modern condensed matter physics and materials science. A new study now demonstrates how...
Researchers from the Institute for Quantum Computing (IQC) at the University of Waterloo led the development of a new extensible wiring technique capable of controlling superconducting quantum bits, representing a significant step towards to the realization of a scalable quantum computer.
"The quantum socket is a wiring method that uses three-dimensional wires based on spring-loaded pins to address individual qubits," said Jeremy Béjanin, a PhD...
In a paper in Scientific Reports, a research team at Worcester Polytechnic Institute describes a novel light-activated phenomenon that could become the basis for applications as diverse as microscopic robotic grippers and more efficient solar cells.
A research team at Worcester Polytechnic Institute (WPI) has developed a revolutionary, light-activated semiconductor nanocomposite material that can be used...
By forcefully embedding two silicon atoms in a diamond matrix, Sandia researchers have demonstrated for the first time on a single chip all the components needed to create a quantum bridge to link quantum computers together.
"People have already built small quantum computers," says Sandia researcher Ryan Camacho. "Maybe the first useful one won't be a single giant quantum computer...
14.10.2016 | Event News
14.10.2016 | Event News
12.10.2016 | Event News
26.10.2016 | Awards Funding
26.10.2016 | Power and Electrical Engineering
26.10.2016 | Health and Medicine