DEEP will be the official German contribution to the world wide operating International Human Epigenome Consortium (IHEC). The DEEP program will be coordinated by Prof. Dr. Jörn Walter, Saarland University.
DEEP forms a network of 21 German expert groups for interdisciplinary epigenome research. DEEP will generate 70 reference epigenome maps of major primary cell/tissue types in normal and diseased states exclusively using NGS technologies. The scientific program focusses on metabolic and inflammatory diseases such as adipositas, fatty liver disease, bowel disease and rheumatic arthritis. DEEP combines strong experimental and bioinformatics expertise in epigenomics.
The goal is to generate high quality reference epigenomes which will be deposited in public repositories coordinated by IHEC. The DEEP epigenome program will be flanked by functional model studies using mouse and human cell systems. This combined program will produce new functional insights in the molecular processes of complex systemic diseases.
The partners in DEEP are: Deutsches Krebsforschungszentrum Heidelberg, Deutsches Rheumaforschungs-Zentrum Berlin, EURICE – European Research and Project Office GmbH , IFADO Dortmund, Institut für Arbeitsmedizin Dortmund, Max-Delbrück-Centrum Berlin, Max-Planck-Institut für Immunologie und Epigenetik Freiburg, Max-Planck-Institut für Informatik Saarbrücken, Max-Planck-Institut für molekulare Genetik Berlin, Quiagen AG Hilden, Sanofi-Aventis Höchst, Universität Duisburg-Essen, Universität Kiel, Universität Münster, Universität Regensburg, Universität des Saarlandes.For further information, please contact:
Thorsten Mohr | Universität des Saarlandes
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Whether you call it effervescent, fizzy, or sparkling, carbonated water is making a comeback as a beverage. Aside from quenching thirst, researchers at the University of Illinois at Urbana-Champaign have discovered a new use for these "bubbly" concoctions that will have major impact on the manufacturer of the world's thinnest, flattest, and one most useful materials -- graphene.
As graphene's popularity grows as an advanced "wonder" material, the speed and quality at which it can be manufactured will be paramount. With that in mind,...
Physicists at the University of Bonn have managed to create optical hollows and more complex patterns into which the light of a Bose-Einstein condensate flows. The creation of such highly low-loss structures for light is a prerequisite for complex light circuits, such as for quantum information processing for a new generation of computers. The researchers are now presenting their results in the journal Nature Photonics.
Light particles (photons) occur as tiny, indivisible portions. Many thousands of these light portions can be merged to form a single super-photon if they are...
For the first time, scientists have shown that circular RNA is linked to brain function. When a RNA molecule called Cdr1as was deleted from the genome of mice, the animals had problems filtering out unnecessary information – like patients suffering from neuropsychiatric disorders.
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An experimental small satellite has successfully collected and delivered data on a key measurement for predicting changes in Earth's climate.
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A study led by scientists of the Max Planck Institute for the Structure and Dynamics of Matter (MPSD) at the Center for Free-Electron Laser Science in Hamburg presents evidence of the coexistence of superconductivity and “charge-density-waves” in compounds of the poorly-studied family of bismuthates. This observation opens up new perspectives for a deeper understanding of the phenomenon of high-temperature superconductivity, a topic which is at the core of condensed matter research since more than 30 years. The paper by Nicoletti et al has been published in the PNAS.
Since the beginning of the 20th century, superconductivity had been observed in some metals at temperatures only a few degrees above the absolute zero (minus...
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