Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:


Genetic differences larger between populations in Northern Europe

Researchers at Karolinska Institutet and Helsinki University have shown that the genetic differences appear larger between the populations in Northern Europe than within Central Europe.

The genetic distance is especially notable between Eastern and Western Finland. The study is published in the science journal PLoS One and is important for the understanding of genetic factors behind human diseases.

- When studying diseases and treatments, it is important to match the studied group with a similar control group. Otherwise the results could be overestimated, when they in fact just shows normal differences between for instance different part of a country, says Professor Juha Kere at Karolinska Institutet in Stockholm.

Human population genetic studies have recently gained a new powerful tool from the analysis of densely spaced single nucleotide polymorphisms (SNPs) across the whole genome. In this study, almost 250 000 such polymorphisms were used to analyze genetic differences between the Germans, British, Eastern and Western Finns and Swedes.

The Germans and British' are genetically close to each other, which also have been observed in other recently published studies. The genetic distances between the Swedes and Finns are somewhat larger. The researchers also found that the genetic difference between Eastern and Western Finland was substantial in a European scale. Even between Finnish counties there were clear differences

- The larger genetic distances in the north are caused by differences in population history. The northernmost parts of Europe were inhabited later than Central Europe and by fewer people, and have had smaller populations since then, says Päivi Lahermo, research team leader at Helsinki University.

Publication: "Genome-Wide Analysis of Single Nucleotide Polymorphisms Uncovers Population Structure in Northern Europe", Elina Salmela, Tuuli Lappalainen, Ingegerd Fransson, Peter M. Andersen, Karin Dahlman-Wright, Andreas Fiebig, Pertti Sistonen, Marja-Liisa Savontaus, Stefan Schreiber, Juha Kere, Päivi Lahermo, PLoS One, 24 oktober 2008

Further information, please contact:

Professor Juha Kere,
Department of Biosciences and Nutrition
Karolinska Institutet
Tel: +46 (0)73-4213550
Dr Päivi Lahermo
Institute for Molecular Medicine Finland
Helsinki University
Tel: +358407206315
Press Officer Katarina Sternudd
Karolinska Institutet
Tel: +46 (0)8-524 838 95
Karolinska Institutet is one of the leading medical universities in Europe. Through research, education and information, Karolinska Institutet contributes to improving human health. Each year, the Nobel Assembly at Karolinska Institutet awards the Nobel Prize in Physiology or Medicine.

Katarina Sternudd | idw
Further information:

More articles from Life Sciences:

nachricht ‘Farming’ bacteria to boost growth in the oceans
24.10.2016 | Max-Planck-Institut für marine Mikrobiologie

nachricht Calcium Induces Chronic Lung Infections
24.10.2016 | Universität Basel

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Light-driven atomic rotations excite magnetic waves

Terahertz excitation of selected crystal vibrations leads to an effective magnetic field that drives coherent spin motion

Controlling functional properties by light is one of the grand goals in modern condensed matter physics and materials science. A new study now demonstrates how...

Im Focus: New 3-D wiring technique brings scalable quantum computers closer to reality

Researchers from the Institute for Quantum Computing (IQC) at the University of Waterloo led the development of a new extensible wiring technique capable of controlling superconducting quantum bits, representing a significant step towards to the realization of a scalable quantum computer.

"The quantum socket is a wiring method that uses three-dimensional wires based on spring-loaded pins to address individual qubits," said Jeremy Béjanin, a PhD...

Im Focus: Scientists develop a semiconductor nanocomposite material that moves in response to light

In a paper in Scientific Reports, a research team at Worcester Polytechnic Institute describes a novel light-activated phenomenon that could become the basis for applications as diverse as microscopic robotic grippers and more efficient solar cells.

A research team at Worcester Polytechnic Institute (WPI) has developed a revolutionary, light-activated semiconductor nanocomposite material that can be used...

Im Focus: Diamonds aren't forever: Sandia, Harvard team create first quantum computer bridge

By forcefully embedding two silicon atoms in a diamond matrix, Sandia researchers have demonstrated for the first time on a single chip all the components needed to create a quantum bridge to link quantum computers together.

"People have already built small quantum computers," says Sandia researcher Ryan Camacho. "Maybe the first useful one won't be a single giant quantum computer...

Im Focus: New Products - Highlights of COMPAMED 2016

COMPAMED has become the leading international marketplace for suppliers of medical manufacturing. The trade fair, which takes place every November and is co-located to MEDICA in Dusseldorf, has been steadily growing over the past years and shows that medical technology remains a rapidly growing market.

In 2016, the joint pavilion by the IVAM Microtechnology Network, the Product Market “High-tech for Medical Devices”, will be located in Hall 8a again and will...

All Focus news of the innovation-report >>>



Event News

#IC2S2: When Social Science meets Computer Science - GESIS will host the IC2S2 conference 2017

14.10.2016 | Event News

Agricultural Trade Developments and Potentials in Central Asia and the South Caucasus

14.10.2016 | Event News

World Health Summit – Day Three: A Call to Action

12.10.2016 | Event News

Latest News

Oasis of life in the ice-covered central Arctic

24.10.2016 | Earth Sciences

‘Farming’ bacteria to boost growth in the oceans

24.10.2016 | Life Sciences

Light-driven atomic rotations excite magnetic waves

24.10.2016 | Physics and Astronomy

More VideoLinks >>>