Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Genetic differences larger between populations in Northern Europe

27.10.2008
Researchers at Karolinska Institutet and Helsinki University have shown that the genetic differences appear larger between the populations in Northern Europe than within Central Europe.

The genetic distance is especially notable between Eastern and Western Finland. The study is published in the science journal PLoS One and is important for the understanding of genetic factors behind human diseases.

- When studying diseases and treatments, it is important to match the studied group with a similar control group. Otherwise the results could be overestimated, when they in fact just shows normal differences between for instance different part of a country, says Professor Juha Kere at Karolinska Institutet in Stockholm.

Human population genetic studies have recently gained a new powerful tool from the analysis of densely spaced single nucleotide polymorphisms (SNPs) across the whole genome. In this study, almost 250 000 such polymorphisms were used to analyze genetic differences between the Germans, British, Eastern and Western Finns and Swedes.

The Germans and British' are genetically close to each other, which also have been observed in other recently published studies. The genetic distances between the Swedes and Finns are somewhat larger. The researchers also found that the genetic difference between Eastern and Western Finland was substantial in a European scale. Even between Finnish counties there were clear differences

- The larger genetic distances in the north are caused by differences in population history. The northernmost parts of Europe were inhabited later than Central Europe and by fewer people, and have had smaller populations since then, says Päivi Lahermo, research team leader at Helsinki University.

Publication: "Genome-Wide Analysis of Single Nucleotide Polymorphisms Uncovers Population Structure in Northern Europe", Elina Salmela, Tuuli Lappalainen, Ingegerd Fransson, Peter M. Andersen, Karin Dahlman-Wright, Andreas Fiebig, Pertti Sistonen, Marja-Liisa Savontaus, Stefan Schreiber, Juha Kere, Päivi Lahermo, PLoS One, 24 oktober 2008

Further information, please contact:

Professor Juha Kere,
Department of Biosciences and Nutrition
Karolinska Institutet
Tel: +46 (0)73-4213550
E-mail: juha.kere@ki.se
Dr Päivi Lahermo
Institute for Molecular Medicine Finland
Helsinki University
Tel: +358407206315
E-mail: paivi.lahermo@helsinki.fi
Press Officer Katarina Sternudd
Karolinska Institutet
Tel: +46 (0)8-524 838 95
E-mail: katarina.sternudd@ki.se
Karolinska Institutet is one of the leading medical universities in Europe. Through research, education and information, Karolinska Institutet contributes to improving human health. Each year, the Nobel Assembly at Karolinska Institutet awards the Nobel Prize in Physiology or Medicine.

Katarina Sternudd | idw
Further information:
http://ki.se
http://dx.plos.org/10.1371/journal.pone.0003519
http://ki.se/pressimages

More articles from Life Sciences:

nachricht Designer cells: artificial enzyme can activate a gene switch
22.05.2018 | Universität Basel

nachricht Flow of cerebrospinal fluid regulates neural stem cell division
22.05.2018 | Helmholtz Zentrum München - Deutsches Forschungszentrum für Gesundheit und Umwelt

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: LZH showcases laser material processing of tomorrow at the LASYS 2018

At the LASYS 2018, from June 5th to 7th, the Laser Zentrum Hannover e.V. (LZH) will be showcasing processes for the laser material processing of tomorrow in hall 4 at stand 4E75. With blown bomb shells the LZH will present first results of a research project on civil security.

At this year's LASYS, the LZH will exhibit light-based processes such as cutting, welding, ablation and structuring as well as additive manufacturing for...

Im Focus: Self-illuminating pixels for a new display generation

There are videos on the internet that can make one marvel at technology. For example, a smartphone is casually bent around the arm or a thin-film display is rolled in all directions and with almost every diameter. From the user's point of view, this looks fantastic. From a professional point of view, however, the question arises: Is that already possible?

At Display Week 2018, scientists from the Fraunhofer Institute for Applied Polymer Research IAP will be demonstrating today’s technological possibilities and...

Im Focus: Explanation for puzzling quantum oscillations has been found

So-called quantum many-body scars allow quantum systems to stay out of equilibrium much longer, explaining experiment | Study published in Nature Physics

Recently, researchers from Harvard and MIT succeeded in trapping a record 53 atoms and individually controlling their quantum state, realizing what is called a...

Im Focus: Dozens of binaries from Milky Way's globular clusters could be detectable by LISA

Next-generation gravitational wave detector in space will complement LIGO on Earth

The historic first detection of gravitational waves from colliding black holes far outside our galaxy opened a new window to understanding the universe. A...

Im Focus: Entangled atoms shine in unison

A team led by Austrian experimental physicist Rainer Blatt has succeeded in characterizing the quantum entanglement of two spatially separated atoms by observing their light emission. This fundamental demonstration could lead to the development of highly sensitive optical gradiometers for the precise measurement of the gravitational field or the earth's magnetic field.

The age of quantum technology has long been heralded. Decades of research into the quantum world have led to the development of methods that make it possible...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

Save the date: Forum European Neuroscience – 07-11 July 2018 in Berlin, Germany

02.05.2018 | Event News

Invitation to the upcoming "Current Topics in Bioinformatics: Big Data in Genomics and Medicine"

13.04.2018 | Event News

Unique scope of UV LED technologies and applications presented in Berlin: ICULTA-2018

12.04.2018 | Event News

 
Latest News

Designer cells: artificial enzyme can activate a gene switch

22.05.2018 | Life Sciences

PR of MCC: Carbon removal from atmosphere unavoidable for 1.5 degree target

22.05.2018 | Earth Sciences

Achema 2018: New camera system monitors distillation and helps save energy

22.05.2018 | Trade Fair News

VideoLinks
Science & Research
Overview of more VideoLinks >>>