The study involved 25,000 women who answered a questionnaire about their history of migraines and migraines with aura. Aura is usually described as visual disturbances, such as flashing lights or geometric patterns. The women were tested for a genetic variant called the angiotensin-converting enzyme (ACE) D/I polymorphism.
A total of 4,577 women reported a history of migraine and of those, 1,275 had migraine with aura. Twelve years after the start of the study, 625 strokes and heart attacks were reported.
The study did not find a link between the gene variant and migraine, migraine with aura, stroke or heart attacks. However, women who had migraine with aura and also were carriers of certain genotypes, called the DD and the DI genotypes, had double the risk of stroke and heart attacks. In contrast, women who had migraine with aura and were carriers of a third genotype, called the II genotype, were not at increased risk. The authors add the caution that this relationship was identified with very little information and must be tested in other studies to determine if it is real.
“The complex relationship among this gene variant, migraine, stroke and heart disease has been the focus of many studies and the results have been controversial,” says study author Markus Schürks, MD, MSc, with the Division of Preventive Medicine at Brigham and Women's Hospital in Boston. “Getting to the bottom of whether there is a connection and why may help to develop ways to prevent issues like stroke and heart disease, which are leading causes of death in the United States.”
The study was supported by the National Heart, Lung, and Blood Institute, the National Cancer Institute, the Donald W. Reynolds Foundation, the Leducq Foundation and the Doris Duke Charitable Foundation.
The American Academy of Neurology, an association of more than 21,000 neurologists and neuroscience professionals, is dedicated to promoting the highest quality patient-centered neurologic care. A neurologist is a doctor with specialized training in diagnosing, treating and managing disorders of the brain and nervous system such as stroke, Alzheimer’s disease, epilepsy, Parkinson’s disease, and multiple sclerosis.
Water forms 'spine of hydration' around DNA, group finds
26.05.2017 | Cornell University
How herpesviruses win the footrace against the immune system
26.05.2017 | Helmholtz-Zentrum für Infektionsforschung
Staphylococcus aureus is a feared pathogen (MRSA, multi-resistant S. aureus) due to frequent resistances against many antibiotics, especially in hospital infections. Researchers at the Paul-Ehrlich-Institut have identified immunological processes that prevent a successful immune response directed against the pathogenic agent. The delivery of bacterial proteins with RNA adjuvant or messenger RNA (mRNA) into immune cells allows the re-direction of the immune response towards an active defense against S. aureus. This could be of significant importance for the development of an effective vaccine. PLOS Pathogens has published these research results online on 25 May 2017.
Staphylococcus aureus (S. aureus) is a bacterium that colonizes by far more than half of the skin and the mucosa of adults, usually without causing infections....
Physicists from the University of Würzburg are capable of generating identical looking single light particles at the push of a button. Two new studies now demonstrate the potential this method holds.
The quantum computer has fuelled the imagination of scientists for decades: It is based on fundamentally different phenomena than a conventional computer....
An international team of physicists has monitored the scattering behaviour of electrons in a non-conducting material in real-time. Their insights could be beneficial for radiotherapy.
We can refer to electrons in non-conducting materials as ‘sluggish’. Typically, they remain fixed in a location, deep inside an atomic composite. It is hence...
Two-dimensional magnetic structures are regarded as a promising material for new types of data storage, since the magnetic properties of individual molecular building blocks can be investigated and modified. For the first time, researchers have now produced a wafer-thin ferrimagnet, in which molecules with different magnetic centers arrange themselves on a gold surface to form a checkerboard pattern. Scientists at the Swiss Nanoscience Institute at the University of Basel and the Paul Scherrer Institute published their findings in the journal Nature Communications.
Ferrimagnets are composed of two centers which are magnetized at different strengths and point in opposing directions. Two-dimensional, quasi-flat ferrimagnets...
An Australian-Chinese research team has created the world's thinnest hologram, paving the way towards the integration of 3D holography into everyday...
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26.05.2017 | Life Sciences
26.05.2017 | Life Sciences
26.05.2017 | Physics and Astronomy