Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

DNA Weaving

16.11.2010
Two-dimensional crystals from DNA origami tiles

DNA is more than just a carrier for our genetic information; DNA is also an outstanding nanoscale building material, as researchers led by Ned Seeman discovered thirty years ago.


Seeman and his colleagues at the New York University (USA) have now used cross-shaped DNA tiles to produce an amazingly large grid structure that resembles woven fabric. As the researchers report in the journal Angewandte Chemie, these two-dimensional crystals attain dimensions of about 2×3 micrometers.

The specific pairing of complementary bases makes DNA an ideal nanoscale building component. It is possible to incorporate particular base sequences that specifically bind to their counterparts. These are called “sticky ends”, and can be used to assemble tailored structures. Many nanostructures and nanomachines have previously been made from DNA. This technology experienced an upsurge a few years ago because of a new twist: the DNA origami technique developed by Paul Rothemund. As in origami, the Japanese art of paper folding, a long single strand of DNA is folded into a desired three-dimensional shape through short synthetic DNA oligonucleotides.

Seeman and his co-workers have also made use of this technique. They used this origami method to fold the DNA into the shapes they needed: cross-shaped tiles. The crosses consist of two mutually orthogonal overlapping strips, like two plasters stuck on top of each other to make a cross. On the four sides of the cross there are several sticky ends; the sticky ends opposite each other are identical. The researchers used two different sets of origami crosses with different sticky ends. These ends are designed so that the crosses bind together in an alternating pattern through a self-organization process—such that the lower strip of one cross is always bound to the upper strip of its neighbor. This results in a two-dimensional structure that has a lattice-like woven appearance when viewed through an electron microscope. The alternating construction of upward and downward curved crosses is necessary to produce a planar surface. Randomly assembled crosses often lead to tubular structures.

“Our new approach could smooth the way for the industrial production of nanostructures through molecular self-organization processes,” hopes Seeman.

Author: Nadrian C. Seeman, New York University (USA), http://chemistry.fas.nyu.edu/object/nadriancseeman.html

Title: Crystalline Two-Dimensional DNA Origami Arrays

Angewandte Chemie International Edition, Permalink to the article: http://dx.doi.org/10.1002/anie.201005911

Nadrian C. Seeman | Angewandte Chemie
Further information:
http://pressroom.angewandte.org
http://chemistry.fas.nyu.edu/object/nadriancseeman.html

More articles from Life Sciences:

nachricht Fine organic particles in the atmosphere are more often solid glass beads than liquid oil droplets
21.04.2017 | Max-Planck-Institut für Chemie

nachricht Study overturns seminal research about the developing nervous system
21.04.2017 | University of California - Los Angeles Health Sciences

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Deep inside Galaxy M87

The nearby, giant radio galaxy M87 hosts a supermassive black hole (BH) and is well-known for its bright jet dominating the spectrum over ten orders of magnitude in frequency. Due to its proximity, jet prominence, and the large black hole mass, M87 is the best laboratory for investigating the formation, acceleration, and collimation of relativistic jets. A research team led by Silke Britzen from the Max Planck Institute for Radio Astronomy in Bonn, Germany, has found strong indication for turbulent processes connecting the accretion disk and the jet of that galaxy providing insights into the longstanding problem of the origin of astrophysical jets.

Supermassive black holes form some of the most enigmatic phenomena in astrophysics. Their enormous energy output is supposed to be generated by the...

Im Focus: A Quantum Low Pass for Photons

Physicists in Garching observe novel quantum effect that limits the number of emitted photons.

The probability to find a certain number of photons inside a laser pulse usually corresponds to a classical distribution of independent events, the so-called...

Im Focus: Microprocessors based on a layer of just three atoms

Microprocessors based on atomically thin materials hold the promise of the evolution of traditional processors as well as new applications in the field of flexible electronics. Now, a TU Wien research team led by Thomas Müller has made a breakthrough in this field as part of an ongoing research project.

Two-dimensional materials, or 2D materials for short, are extremely versatile, although – or often more precisely because – they are made up of just one or a...

Im Focus: Quantum-physical Model System

Computer-assisted methods aid Heidelberg physicists in reproducing experiment with ultracold atoms

Two researchers at Heidelberg University have developed a model system that enables a better understanding of the processes in a quantum-physical experiment...

Im Focus: Glacier bacteria’s contribution to carbon cycling

Glaciers might seem rather inhospitable environments. However, they are home to a diverse and vibrant microbial community. It’s becoming increasingly clear that they play a bigger role in the carbon cycle than previously thought.

A new study, now published in the journal Nature Geoscience, shows how microbial communities in melting glaciers contribute to the Earth’s carbon cycle, a...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Expert meeting “Health Business Connect” will connect international medical technology companies

20.04.2017 | Event News

Wenn der Computer das Gehirn austrickst

18.04.2017 | Event News

7th International Conference on Crystalline Silicon Photovoltaics in Freiburg on April 3-5, 2017

03.04.2017 | Event News

 
Latest News

New quantum liquid crystals may play role in future of computers

21.04.2017 | Physics and Astronomy

A promising target for kidney fibrosis

21.04.2017 | Health and Medicine

Light rays from a supernova bent by the curvature of space-time around a galaxy

21.04.2017 | Physics and Astronomy

VideoLinks
B2B-VideoLinks
More VideoLinks >>>