Experts from the School of Veterinary Medicine and Science have discovered powerful antibiotic properties in the brains of cockroaches and locusts which could lead to novel treatments for multi-drug resistant bacterial infections. They found that the tissues of the brain and nervous system of the insects were able to kill more than 90 per cent of MRSA and pathogenic Escherichia coli, without harming human cells.
Simon Lee, a postgraduate researcher, is presenting their work at the Society for General Microbiology’s autumn meeting which is being held at The University of Nottingham between the 6 and 9 September 2010. The research has identified up to nine different molecules in the insect tissues that were toxic to bacteria.
Simon Lee said: “We hope that these molecules could eventually be developed into treatments for E. coli and MRSA infections that are increasingly resistant to current drugs. These new antibiotics could potentially provide alternatives to currently available drugs that may be effective but have serious and unwanted side effects.”
Dr Naveed Khan, an Associate Professor of Molecular Microbiology who is supervising Simon Lee’s work said: “Superbugs such as MRSA have developed resistance against the chemotherapeutic artillery that we throw at them. They have shown the ability to cause untreatable infections, and have become a major threat in our fight against bacterial diseases. Thus, there is a continuous need to find additional sources of novel antimicrobials to confront this menace.”
Using state-of-the-art analytical tools, Dr Khan and his team are studying the specific properties of the antibacterial molecules. Research is currently underway to test the potency of these molecules against a variety of emerging superbugs such as Acinetobacter, Pseudomonas and Burkholderia.
Mr Lee explained why it is unsurprising that insects secrete their own antimicrobials. He said: “Insects often live in unsanitary and unhygienic environments where they encounter many different types of bacteria. It is therefore logical that they have developed ways of protecting themselves against micro-organisms.”
Lindsay Brooke | EurekAlert!
Newly designed molecule binds nitrogen
23.02.2018 | Julius-Maximilians-Universität Würzburg
Atomic Design by Water
23.02.2018 | Max-Planck-Institut für Eisenforschung GmbH
A newly developed laser technology has enabled physicists in the Laboratory for Attosecond Physics (jointly run by LMU Munich and the Max Planck Institute of Quantum Optics) to generate attosecond bursts of high-energy photons of unprecedented intensity. This has made it possible to observe the interaction of multiple photons in a single such pulse with electrons in the inner orbital shell of an atom.
In order to observe the ultrafast electron motion in the inner shells of atoms with short light pulses, the pulses must not only be ultrashort, but very...
A group of researchers led by Andrea Cavalleri at the Max Planck Institute for Structure and Dynamics of Matter (MPSD) in Hamburg has demonstrated a new method enabling precise measurements of the interatomic forces that hold crystalline solids together. The paper Probing the Interatomic Potential of Solids by Strong-Field Nonlinear Phononics, published online in Nature, explains how a terahertz-frequency laser pulse can drive very large deformations of the crystal.
By measuring the highly unusual atomic trajectories under extreme electromagnetic transients, the MPSD group could reconstruct how rigid the atomic bonds are...
Quantum computers may one day solve algorithmic problems which even the biggest supercomputers today can’t manage. But how do you test a quantum computer to...
For the first time, a team of researchers at the Max-Planck Institute (MPI) for Polymer Research in Mainz, Germany, has succeeded in making an integrated circuit (IC) from just a monolayer of a semiconducting polymer via a bottom-up, self-assembly approach.
In the self-assembly process, the semiconducting polymer arranges itself into an ordered monolayer in a transistor. The transistors are binary switches used...
Breakthrough provides a new concept of the design of molecular motors, sensors and electricity generators at nanoscale
Researchers from the Institute of Organic Chemistry and Biochemistry of the CAS (IOCB Prague), Institute of Physics of the CAS (IP CAS) and Palacký University...
15.02.2018 | Event News
13.02.2018 | Event News
12.02.2018 | Event News
23.02.2018 | Physics and Astronomy
23.02.2018 | Health and Medicine
23.02.2018 | Physics and Astronomy