The 4 different screening plates deliver 128 selective resins based on high-performance, Molecularly Imprinted Polymers (MIPs). Biotage provides professional MIPs technical consultation, information on additional formats as well as assistance with data interpretation and process development.
ExploraSep screening plates support rapid method development, reduced cycle times and allow the identification of selective molecular imprinted polymers for impurities such as genotoxins; currently a major concern for the pharmaceutical industry. Candidate MIPs identified during screening can be ordered separately for confirmation studies and then transferred to preparative or process scale applications.
ExploraSep screening plates contain a unique collection of proprietary separation phases based on MIPs and their non-imprinted homologs. The polymers are grouped so that each plate is themed and will target a particular class of impurities. Plate A can be used for screening polar, basic (e.g. amines), neutral (e.g. amides, or esters), and acidic (carboxylic acid) compounds. Plate U targets screening phosphates, phosphonates, sulphates and sulphonates, peptides, proteins as well as anions of carboxylic acids and more weakly binding lactones and neutral phosphates. Plate C can be used for screening 1,2- and 1,3-diols, a-hydroxycarboxylic acids, carbohydrates and hydrophillic peptides under basic conditions. Plate H polymers target non-polar and aromatic compounds.
Like a lock and key, molecularly imprinted polymers bind impurities, not just by chemical means, but also by spatial recognition. This dual-mechanism enables MIPs to be highly selective, working effectively at very low concentrations, getting down to very low impurity levels. In increasingly challenging regulatory climates, MIPs show excellent promise for being able to keep up with ever-tightening regulations. ExploraSep is ideal for researchers working with proprietary compounds, or with highly regulated compounds in many industries such as waste, environmental, chemical, consumer products, pharmaceutical process and more.
Biotage’s process-consumables and scavenging products are supported by a wealth of knowledge and experience in method development and support. “Biotage experts help to guide customers in choosing the right product and most efficient method that best suits their work-flow and development needs”, says Scott Carr, VP of Commercial Operations. “We bring exceptional support to our customers. This new generation of scavenging media raises the bar in terms of product performance and also reflects Biotage’s expertise and continued commitment to the industry.”
For further information please call Biotage or visit www.biotage.com: in Europe +46 18 56 57 10, in North America toll free 1 800 446 4752, in Japan +81 422 28 1233, other areas please call +46 18 56 57 10.
Rob Thompson | b3c newswire
A novel socio-ecological approach helps identifying suitable wolf habitats
17.02.2017 | Universität Zürich
New, ultra-flexible probes form reliable, scar-free integration with the brain
16.02.2017 | University of Texas at Austin
In the field of nanoscience, an international team of physicists with participants from Konstanz has achieved a breakthrough in understanding heat transport
Cells need to repair damaged DNA in our genes to prevent the development of cancer and other diseases. Our cells therefore activate and send “repair-proteins”...
The Fraunhofer IWS Dresden and Technische Universität Dresden inaugurated their jointly operated Center for Additive Manufacturing Dresden (AMCD) with a festive ceremony on February 7, 2017. Scientists from various disciplines perform research on materials, additive manufacturing processes and innovative technologies, which build up components in a layer by layer process. This technology opens up new horizons for component design and combinations of functions. For example during fabrication, electrical conductors and sensors are already able to be additively manufactured into components. They provide information about stress conditions of a product during operation.
The 3D-printing technology, or additive manufacturing as it is often called, has long made the step out of scientific research laboratories into industrial...
Nature does amazing things with limited design materials. Grass, for example, can support its own weight, resist strong wind loads, and recover after being...
Nanometer-scale magnetic perforated grids could create new possibilities for computing. Together with international colleagues, scientists from the Helmholtz Zentrum Dresden-Rossendorf (HZDR) have shown how a cobalt grid can be reliably programmed at room temperature. In addition they discovered that for every hole ("antidot") three magnetic states can be configured. The results have been published in the journal "Scientific Reports".
Physicist Dr. Rantej Bali from the HZDR, together with scientists from Singapore and Australia, designed a special grid structure in a thin layer of cobalt in...
13.02.2017 | Event News
10.02.2017 | Event News
09.02.2017 | Event News
17.02.2017 | Medical Engineering
17.02.2017 | Medical Engineering
17.02.2017 | Health and Medicine