This is one of the findings of a translational research project conducted by the Austrian Science Fund FWF. The project demonstrated how 3D models and special mathematical methods could be used to improve the design and integration of implants in the body on a patient-specific basis.
Data was gathered from computer and magnetic resonance tomography and used to generate 3D models specifically for shoulder joints and their replacements. The data was analysed in a procedure known as the finite element method, and possible individual optimisations were calculated. The project exemplifies the acute benefit of research findings from the Translational Research Programme, which ended at the close of the first quarter of 2012.
Basic research forms the foundation for future applications, as illustrated by programmes like the Translational Research Programme. This programme, which the Austrian Science Fund (FWF) conducted on behalf of the country´s Federal Ministry for Transport, Innovation and Technology (BMVIT), ran until early 2012 and served to accelerate the transfer of basic knowledge into practical applications: Applications which, first and foremost, improve the quality of people´s lives, in addition to creating economic value. Take project L526, for example.
SHOULDER TO SHOULDER: MATHEMATICS & MEDICINE This project brought together basic scientific knowledge from the areas of mathematics, medicine and computer science with the aim of optimising replacement shoulder joints individually (patient-specific). Headed by Dr. Karl Entacher from Salzburg University of Applied Sciences and Dr. Peter Schuller-Götzburg from the Paracelsus Medical University in Salzburg, the project initially computed human shoulder joint models and then used them as the basis for the analytical simulation of varying load conditions.
The team commenced by using imaging techniques to create the computer models. To this effect, computer tomography was used to build up images of human shoulder joints on a layer-by-layer basis. As Dr. Entacher explains: "Modern tomography techniques allow us to create images of an entire shoulder joint layer-by-layer, and the layer thicknesses that we can achieve today make excellent resolution possible. We were able to use this image data to create computer-generated 3D models of each patient´s individual shoulder joint, forming the basis for our subsequent analysis."FINITE FINDINGS
Commenting on the personal significance of the project and the end of the Translational Research Programme, Dr. Entacher says: "As a basic researcher, it is very satisfying to see how working with physicians and engineers can turn our findings into specific applications that can help people. In fact, I feel it provides a more personal perspective on personal development. In addition to this personal experience, the Translational Research Programme also makes a significant contribution to innovation culture in Austria. A contribution that will be missing in the future."Image and text available from Monday, April 30 2012, 09.00 CET at:
Margot Pechtigam | PR&D
Bergamotene - alluring and lethal for Manduca sexta
21.04.2017 | Max-Planck-Institut für chemische Ökologie
How to color a lizard: From biology to mathematics
13.04.2017 | Université de Genève
Staphylococcus aureus is a feared pathogen (MRSA, multi-resistant S. aureus) due to frequent resistances against many antibiotics, especially in hospital infections. Researchers at the Paul-Ehrlich-Institut have identified immunological processes that prevent a successful immune response directed against the pathogenic agent. The delivery of bacterial proteins with RNA adjuvant or messenger RNA (mRNA) into immune cells allows the re-direction of the immune response towards an active defense against S. aureus. This could be of significant importance for the development of an effective vaccine. PLOS Pathogens has published these research results online on 25 May 2017.
Staphylococcus aureus (S. aureus) is a bacterium that colonizes by far more than half of the skin and the mucosa of adults, usually without causing infections....
Physicists from the University of Würzburg are capable of generating identical looking single light particles at the push of a button. Two new studies now demonstrate the potential this method holds.
The quantum computer has fuelled the imagination of scientists for decades: It is based on fundamentally different phenomena than a conventional computer....
An international team of physicists has monitored the scattering behaviour of electrons in a non-conducting material in real-time. Their insights could be beneficial for radiotherapy.
We can refer to electrons in non-conducting materials as ‘sluggish’. Typically, they remain fixed in a location, deep inside an atomic composite. It is hence...
Two-dimensional magnetic structures are regarded as a promising material for new types of data storage, since the magnetic properties of individual molecular building blocks can be investigated and modified. For the first time, researchers have now produced a wafer-thin ferrimagnet, in which molecules with different magnetic centers arrange themselves on a gold surface to form a checkerboard pattern. Scientists at the Swiss Nanoscience Institute at the University of Basel and the Paul Scherrer Institute published their findings in the journal Nature Communications.
Ferrimagnets are composed of two centers which are magnetized at different strengths and point in opposing directions. Two-dimensional, quasi-flat ferrimagnets...
An Australian-Chinese research team has created the world's thinnest hologram, paving the way towards the integration of 3D holography into everyday...
24.05.2017 | Event News
23.05.2017 | Event News
22.05.2017 | Event News
26.05.2017 | Life Sciences
26.05.2017 | Life Sciences
26.05.2017 | Physics and Astronomy