Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

VTT developed a software tool for integrating and analysing complex medical data

26.04.2007
MegNet(r) can be used in search of biomarkers of different diseases

VTT Technical Research Centre of Finland developed a new software tool megNet(r) for integration and visualization of complex life science and biomedical data. The new tool can be applied in understanding complex relations in living organisms, and characterizing various diseases, such as cardiac diseases and diabetes.

There has long been a pressing need to exploit efficiently research results in patient care. One of the key problems has been in linking clinically relevant information to the knowledge obtained across multiple disciplines, experimental platforms, and biological systems.

The megNet(r) enables integrative mining of, e.g., molecular interactions, genomes, gene expression profiles, metabolic profiles, medical images and clinical data. VTT is currently applying the megNet(r) to combine medical image and metabolomic data in search of new biomarkers for various diseases. The objective is also to link preclinical and clinical data in pharmaceutical development and healthcare with megNet(r)-tool.

VTT has applied in the development work of megNet(r) conceptual space theory for mining and visualizing life science and medical data. This includes state-of-the-art 3D techniques, mathematical modelling and contextualization. The theory of conceptual spaces combines elements from other theories in cognitive science, psychology and linguistics. It is based on the topological analysis of the information space that enables similarity to be modelled and computed in a natural way. It suits well for integration of complex clinical data such as medical images with molecular level information.

VTT has already applied the megNet(r) software tool in its research projects. In the VISUBIOMED project the researchers analyzed cardiac magnetic resonance images and in future other clinical data related to cardiac diseases. Metabolomics analyses can be performed from serum samples of the same patients. The data was complemented with molecular network information and with information on molecular interactions related to the disease. In the TRANSCENDO project VTT applied the megNet(r) in order to elucidate molecular pathways in the early stages of type 1 diabetes.

The work has been done in collaboration with hospitals.

VTT Technical Research Centre of Finland is the biggest contract research organization in Northern Europe. VTT provides high-end technology solutions and innovation services. From its wide knowledge base, VTT can combine different technologies, create new innovations and a substantial range of world-class technologies and applied research services, thus improving its clients' competitiveness and competence. Through its international scientific and technology network, VTT can produce information, upgrade technology knowledge and create business intelligence and value added to its stakeholders.

Press Office | alfa
Further information:
http://www.vtt.fi/?lang=en
http://www.vtt.fi/kuvat/uutta/megNet.jpg

More articles from Information Technology:

nachricht Ultra-precise chip-scale sensor detects unprecedentedly small changes at the nanoscale
18.01.2017 | The Hebrew University of Jerusalem

nachricht Data analysis optimizes cyber-physical systems in telecommunications and building automation
18.01.2017 | Fraunhofer-Institut für Algorithmen und Wissenschaftliches Rechnen SCAI

All articles from Information Technology >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Traffic jam in empty space

New success for Konstanz physicists in studying the quantum vacuum

An important step towards a completely new experimental access to quantum physics has been made at University of Konstanz. The team of scientists headed by...

Im Focus: How gut bacteria can make us ill

HZI researchers decipher infection mechanisms of Yersinia and immune responses of the host

Yersiniae cause severe intestinal infections. Studies using Yersinia pseudotuberculosis as a model organism aim to elucidate the infection mechanisms of these...

Im Focus: Interfacial Superconductivity: Magnetic and superconducting order revealed simultaneously

Researchers from the University of Hamburg in Germany, in collaboration with colleagues from the University of Aarhus in Denmark, have synthesized a new superconducting material by growing a few layers of an antiferromagnetic transition-metal chalcogenide on a bismuth-based topological insulator, both being non-superconducting materials.

While superconductivity and magnetism are generally believed to be mutually exclusive, surprisingly, in this new material, superconducting correlations...

Im Focus: Studying fundamental particles in materials

Laser-driving of semimetals allows creating novel quasiparticle states within condensed matter systems and switching between different states on ultrafast time scales

Studying properties of fundamental particles in condensed matter systems is a promising approach to quantum field theory. Quasiparticles offer the opportunity...

Im Focus: Designing Architecture with Solar Building Envelopes

Among the general public, solar thermal energy is currently associated with dark blue, rectangular collectors on building roofs. Technologies are needed for aesthetically high quality architecture which offer the architect more room for manoeuvre when it comes to low- and plus-energy buildings. With the “ArKol” project, researchers at Fraunhofer ISE together with partners are currently developing two façade collectors for solar thermal energy generation, which permit a high degree of design flexibility: a strip collector for opaque façade sections and a solar thermal blind for transparent sections. The current state of the two developments will be presented at the BAU 2017 trade fair.

As part of the “ArKol – development of architecturally highly integrated façade collectors with heat pipes” project, Fraunhofer ISE together with its partners...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Sustainable Water use in Agriculture in Eastern Europe and Central Asia

19.01.2017 | Event News

12V, 48V, high-voltage – trends in E/E automotive architecture

10.01.2017 | Event News

2nd Conference on Non-Textual Information on 10 and 11 May 2017 in Hannover

09.01.2017 | Event News

 
Latest News

Helmholtz International Fellow Award for Sarah Amalia Teichmann

20.01.2017 | Awards Funding

An innovative high-performance material: biofibers made from green lacewing silk

20.01.2017 | Materials Sciences

Ion treatments for cardiac arrhythmia — Non-invasive alternative to catheter-based surgery

20.01.2017 | Life Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>