Professor Derek Hill, Chief Executive Officer of IXICO Ltd, said: “The current approaches to medical image analysis in clinical trials rely on highly-skilled radiologists and technicians ‘reading’ and painstakingly comparing images that are often acquired at different centres and different points in time. This process is expensive, time consuming and subject to error.
Our service is completely automated and uses sensitive and reproducible algorithms to quantify changes in the patient over time and hence assess the effectiveness or ineffectiveness of a treatment during trials. It can also compensate for the misplacement or movement of a patient in the scanner, compare images taken at different points in time and provide a full audit trial of the analysis process. As our service is scaleable, it can be used to analyse thousands of images in very early drug tests or in late phase trials. The end result for patients is the faster development of new, more effective treatments for painful or life threatening conditions.”
IXICO’s service has been shown to be effective in a wide variety of medical applications though the company’s initial focus is on developing its services to assess the impact of new drugs for rheumatoid arthritis, dementia and oncology. Clients include a number of major pharmaceutical and healthcare companies, for whom IXICO designs bespoke services, and the company is in advanced negotiations with additional prospective customers.
Professor Hill said: “A key feature of our technology is that the image analysis workflows in the programmes can be easily reconfigured to suit the specific requirements of different pharmaceutical companies. And we have designed our technology platform so that their staff can access the analysis results from computers in a variety of locations via a secure web portal.”
This is IXICO’s first institutional fundraising round and follows its recent success in securing a prestigious £140,000 DTI Grant for Research & Development through the London Development Agency.
Professor Hill commented on the fundraising process: “We are delighted with the success of this funding round. We spoke to several funds but were happy to work with The Capital Fund as they were prepared to share the risk with us and our angel investors by providing vital capital on straightforward terms. They have also helped us to introduce key disciplines that will be particularly useful as we grow the business.”
The Capital Fund’s Investment Manager, Helen Reynolds, said: “IXICO has created a truly innovative technology that has the potential for use across a wide range of medical applications. We were impressed by the quality of the research behind the company’s service and the calibre of the management team, especially Derek Hill, who combine substantial experience of the healthcare industry with significant image analysis acquisition know-how. We wish Derek Hill and his team every success with their future plans.”
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Among the general public, solar thermal energy is currently associated with dark blue, rectangular collectors on building roofs. Technologies are needed for aesthetically high quality architecture which offer the architect more room for manoeuvre when it comes to low- and plus-energy buildings. With the “ArKol” project, researchers at Fraunhofer ISE together with partners are currently developing two façade collectors for solar thermal energy generation, which permit a high degree of design flexibility: a strip collector for opaque façade sections and a solar thermal blind for transparent sections. The current state of the two developments will be presented at the BAU 2017 trade fair.
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At TU Wien, an alternative for resource intensive formwork for the construction of concrete domes was developed. It is now used in a test dome for the Austrian Federal Railways Infrastructure (ÖBB Infrastruktur).
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Many pathogens use certain sugar compounds from their host to help conceal themselves against the immune system. Scientists at the University of Bonn have now, in cooperation with researchers at the University of York in the United Kingdom, analyzed the dynamics of a bacterial molecule that is involved in this process. They demonstrate that the protein grabs onto the sugar molecule with a Pac Man-like chewing motion and holds it until it can be used. Their results could help design therapeutics that could make the protein poorer at grabbing and holding and hence compromise the pathogen in the host. The study has now been published in “Biophysical Journal”.
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UMD, NOAA collaboration demonstrates suitability of in-orbit datasets for weather satellite calibration
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Fiber-reinforced plastics (FRP) are frequently used in the aeronautic and automobile industry. However, the repair of workpieces made of these composite materials is often less profitable than exchanging the part. In order to increase the lifetime of FRP parts and to make them more eco-efficient, the Laser Zentrum Hannover e.V. (LZH) and the Apodius GmbH want to combine a new measuring device for fiber layer orientation with an innovative laser-based repair process.
Defects in FRP pieces may be production or operation-related. Whether or not repair is cost-effective depends on the geometry of the defective area, the tools...
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