One of the findings they have made with this "model brain" is a mechanism in the brain´s neuronal network that restricts the number of items we can normally store in our working memories at any one time to around two to seven.
Working memory, which is our ability to retain and process information over short periods of time, is essential to most cognitive processes, such as thinking, language and planning. It has long been known that the working memory is subject to limitations, as we can only manage to "juggle" a certain number of mnemonic items at any one time. Functional magnetic resonance imagery (fMRI) has revealed that the frontal and parietal lobes are activated when a sequence of two pictures is to be retained briefly in visual working memory. However, just how the nerve cells work together to handle this task has remained a mystery.
The study, which is published in the journal PNAS, is based on a multidisciplinary project co-run by two research teams at KI led by professors Torkel Klingberg and Jesper Tegnér. Most of the work was conducted by doctors Fredrik Edin and Albert Compte, the latter of whom is currently principal investigator of the theoretical neurobiology group at IDIBAPS in Barcelona.
For their project, the researchers used techniques from different scientific fields, applying them to previously known data on how nerve cells and their synapses function biochemically and electrophysiologically. They then developed, using mathematical tools, a form of virtual or computer simulated model brain. The computations carried out with this "model brain" were tested using fMRI experiments, which allowed the researchers to confirm that the computations genuinely gave answers to the questions they asked."It´s like a computer programme for aircraft designers," says Fredrik Edin, PhD in computational neuroscience. "Before testing the design for real, you feed in data on material and aerodynamics and so on to get an idea of how the plan´s going to fly."
"The model predicts, for instance, that increased activation of the frontal lobes will improve working memory," continues Dr Edin. "This finding was also replicable in follow-up fMRI experiments on humans. Working memory is a bottleneck for the human brain´s capacity to process information. These results give us fresh insight into what the bottleneck consists of."
Katarina Sternudd | EurekAlert!
Further reports about: > Aerodynamics > Functional magnetic resonance imagery > Language > Planning > Thinking > brain´s neuronal network > computer programme for aircraft designers > computer simulations > fMRI > limitations of working memory > model brain > nerve cells > theoretical neurobiology > working memory
Deep Learning predicts hematopoietic stem cell development
21.02.2017 | Helmholtz Zentrum München - Deutsches Forschungszentrum für Gesundheit und Umwelt
Sensors embedded in sports equipment could provide real-time analytics to your smartphone
16.02.2017 | University of Illinois College of Engineering
In the field of nanoscience, an international team of physicists with participants from Konstanz has achieved a breakthrough in understanding heat transport
Cells need to repair damaged DNA in our genes to prevent the development of cancer and other diseases. Our cells therefore activate and send “repair-proteins”...
The Fraunhofer IWS Dresden and Technische Universität Dresden inaugurated their jointly operated Center for Additive Manufacturing Dresden (AMCD) with a festive ceremony on February 7, 2017. Scientists from various disciplines perform research on materials, additive manufacturing processes and innovative technologies, which build up components in a layer by layer process. This technology opens up new horizons for component design and combinations of functions. For example during fabrication, electrical conductors and sensors are already able to be additively manufactured into components. They provide information about stress conditions of a product during operation.
The 3D-printing technology, or additive manufacturing as it is often called, has long made the step out of scientific research laboratories into industrial...
Nature does amazing things with limited design materials. Grass, for example, can support its own weight, resist strong wind loads, and recover after being...
Nanometer-scale magnetic perforated grids could create new possibilities for computing. Together with international colleagues, scientists from the Helmholtz Zentrum Dresden-Rossendorf (HZDR) have shown how a cobalt grid can be reliably programmed at room temperature. In addition they discovered that for every hole ("antidot") three magnetic states can be configured. The results have been published in the journal "Scientific Reports".
Physicist Dr. Rantej Bali from the HZDR, together with scientists from Singapore and Australia, designed a special grid structure in a thin layer of cobalt in...
13.02.2017 | Event News
10.02.2017 | Event News
09.02.2017 | Event News
24.02.2017 | Life Sciences
24.02.2017 | Life Sciences
24.02.2017 | Trade Fair News