Phagocytes versus killer cells – A closer look into the tumour tissue

© UDE/Frank Preuß

„It was already known that cancer patients that have many of these immune cells migrated into their tumour tissue have reduced survival rates”, says Sven Brandau, head of the Department of Experimental und Translational Research.

„Therefore, experts suspected that those phagocytic cells, the so-called neutrophils, could inhibit the fight of the killer immune cells against cancer.“

Using advanced microscopy technologies and analyses, Brandau and his collaborators have now uncovered the interaction between the neutrophils and killer cells in tumour tissue. „We were able to show that the neutrophils actually touch the killer cells and prevent the killing of the cancer cells.“

In future investigations, the researchers at the UK Essen would like to block the entry of the phagocytes into the tumour tissue in order to develop novel immunotherapies against cancer.

Cooperation partners in the study were teams from dermatology and experimental immunology.

Editor: Milena Hänisch, Phone +49 201/723-6274, milena.haenisch@uk-essen.de
Translation: Alexandra Niessen, Phone +49 203/37 9-1487, alexandra.niessen@uni-due.de

Prof. Dr. Sven Brandau, Phone: +49 201/723-3193, Sven.brandau@uk-essen.de

https://immunology.sciencemag.org/

Media Contact

Dr. Alexandra Nießen idw - Informationsdienst Wissenschaft

Weitere Informationen:

http://www.uni-duisburg-essen.de/

Alle Nachrichten aus der Kategorie: Life Sciences

Articles and reports from the Life Sciences area deal with applied and basic research into modern biology, chemistry and human medicine.

Valuable information can be found on a range of life sciences fields including bacteriology, biochemistry, bionics, bioinformatics, biophysics, biotechnology, genetics, geobotany, human biology, marine biology, microbiology, molecular biology, cellular biology, zoology, bioinorganic chemistry, microchemistry and environmental chemistry.

Zurück zur Startseite

Kommentare (0)

Schreib Kommentar

Neueste Beiträge

Taking 2D materials for a spin

Scientists at the University of Tsukuba and the Institute of High Pressure Physics fabricate a novel molybdenum disulfide transistor and create an image of the spins of the electrons passing…

Life’s rich pattern

Researchers use sound to shape the future of printing. Researchers in the UK have developed a way to coax microscopic particles and droplets into precise patterns by harnessing the power…

Tantalizing signs of phase-change ‘turbulence’ in RHIC collisions

Fluctuations in net proton production hint at a possible ‘critical point’ marking a change in the way nuclear matter transforms from one phase to another. Physicists studying collisions of gold…

Partners & Sponsors