Technology invented by scientists from The Johns Hopkins University and Ben-Gurion University of the Negev can make three-dimensional imaging quicker, easier, less expensive and more accurate, the researchers said.
This new technology, dubbed FINCH, for Fresnel incoherent correlation holography, could have implications in medical applications such as endoscopy, ophthalmology, CT scanning, X-ray imaging and ultrasounds, co-inventor Gary Brooker said. It may also be applicable to homeland security screening, 3-D photography and 3-D video, he said.
A report presenting the first demonstration of this technology -- with a 3-D microscope called a FINCHSCOPE -- will appear in the March issue of Nature Photonics and will be available on the Nature Photonics Web site on Feb. 17.
“Normally, 3-D imaging requires taking multiple images on multiple planes and then reconstructing the images,” said Brooker, director of the Johns Hopkins University Microscopy Center on the university’s Montgomery County Campus.
“This is a slow process that is restricted to microscope objectives that have less than optimal resolving power,” said Brooker, a research professor of chemistry in Krieger School of Arts and Sciences who also has an appointment in the Whiting School of Engineering Advanced Technology Laboratory. "For this reason, holography currently is not widely applied to the field of 3-D fluorescence microscopic imaging.”
The FINCH technology and the FINCHSCOPE uses microscope objectives with the highest resolving power, a spatial light modulator, a charge-coupled device camera and some simple filters to enable the acquisition of 3-D microscopic images without the need for scanning multiple planes.
The Nature Photonics article reports on a use of the FINCHSCOPE to take a 3-D still image, but moving 3-D images are coming, said Brooker and co-inventor Joseph Rosen, professor of electrical and computer engineering at Ben-Gurion University of the Negev in Israel.
“With traditional 3-D imaging, you cannot capture a moving object,” Brooker said. “With the FINCHSCOPE, you can photograph multiple planes at once, enabling you to capture a 3-D image of a moving object. Researchers now will be able to track biological events happening quickly in cells.”
"In addition, the FINCH technique shows great promise in rapidly recording 3-D information in any scene, independent of illumination,” Rosen said.
Robin Ferrier | EurekAlert!
What happens when we heat the atomic lattice of a magnet all of a sudden?
17.07.2018 | Forschungsverbund Berlin
Subaru Telescope helps pinpoint origin of ultra-high energy neutrino
16.07.2018 | National Institutes of Natural Sciences
For the first time ever, scientists have determined the cosmic origin of highest-energy neutrinos. A research group led by IceCube scientist Elisa Resconi, spokesperson of the Collaborative Research Center SFB1258 at the Technical University of Munich (TUM), provides an important piece of evidence that the particles detected by the IceCube neutrino telescope at the South Pole originate from a galaxy four billion light-years away from Earth.
To rule out other origins with certainty, the team led by neutrino physicist Elisa Resconi from the Technical University of Munich and multi-wavelength...
For the first time a team of researchers have discovered two different phases of magnetic skyrmions in a single material. Physicists of the Technical Universities of Munich and Dresden and the University of Cologne can now better study and understand the properties of these magnetic structures, which are important for both basic research and applications.
Whirlpools are an everyday experience in a bath tub: When the water is drained a circular vortex is formed. Typically, such whirls are rather stable. Similar...
Physicists working with Roland Wester at the University of Innsbruck have investigated if and how chemical reactions can be influenced by targeted vibrational excitation of the reactants. They were able to demonstrate that excitation with a laser beam does not affect the efficiency of a chemical exchange reaction and that the excited molecular group acts only as a spectator in the reaction.
A frequently used reaction in organic chemistry is nucleophilic substitution. It plays, for example, an important role in in the synthesis of new chemical...
Optical spectroscopy allows investigating the energy structure and dynamic properties of complex quantum systems. Researchers from the University of Würzburg present two new approaches of coherent two-dimensional spectroscopy.
"Put an excitation into the system and observe how it evolves." According to physicist Professor Tobias Brixner, this is the credo of optical spectroscopy....
Ultra-short, high-intensity X-ray flashes open the door to the foundations of chemical reactions. Free-electron lasers generate these kinds of pulses, but there is a catch: the pulses vary in duration and energy. An international research team has now presented a solution: Using a ring of 16 detectors and a circularly polarized laser beam, they can determine both factors with attosecond accuracy.
Free-electron lasers (FELs) generate extremely short and intense X-ray flashes. Researchers can use these flashes to resolve structures with diameters on the...
13.07.2018 | Event News
12.07.2018 | Event News
03.07.2018 | Event News
17.07.2018 | Information Technology
17.07.2018 | Materials Sciences
17.07.2018 | Power and Electrical Engineering