Patients with obstructive sleep apnea have the same early cardiovascular damage as diabetics, according to research presented at EUROECHO and other Imaging Modalities 2012. The study1 was presented by Dr Raluca Mincu from Bucharest, Romania.
EUROECHO and other Imaging Modalities 2012 is the annual meeting of the European Association of Cardiovascular Imaging (EACVI)2, a registered branch of the European Society of Cardiology (ESC)3. It takes place 5-8 December in Athens, Greece, at the Megaron Athens International Conference Centre.
Obstructive sleep apnea (OSA) is a common sleep disorder that has been associated with cardiovascular disease. OSA increases the risk of hypertension, arrhythmias, myocardial infarction, stroke, sudden cardiac death and heart failure.
Dr Mincu said: "There are not enough studies in the medical literature on early cardiovascular dysfunction in patients with OSA, when active steps can be taken to prevent progression to heart failure."
She added: "Because OSA leads to so many cardiovascular disorders, we compared early cardiovascular dysfunction in OSA patients and patients with diabetes mellitus, which is a typical risk factor for cardiovascular disease."
The study assessed endothelial and arterial function in 20 patients with moderate to severe OSA (and no diabetes), 20 patients with treated type 2 diabetes mellitus (matched for age, sex and cardiovascular risk factors), and 20 healthy controls (age and sex matched).
In all subjects, arterial function was assessed by intima-media thickness (IMT). Arterial stiffness was measured by young elastic modulus, beta stiffness index, arterial compliance, first systolic peak and second systolic peak. Endothelial function was assessed by flow mediated dilatation (FMD).
Dr Mincu said: "Patients with moderate to severe OSA had endothelial dysfunction and higher arterial stiffness than controls, and their results were similar to patients with diabetes mellitus. This suggests that OSA is associated with a high risk for cardiovascular disease."
She added: "Patients in the OSA and diabetes groups had a higher intima-media thickness, which shows that their arteries are remodelled in a pathological way."
All five parameters of arterial stiffness were significantly higher in the OSA and diabetes mellitus groups compared to controls. FMD was lower in these groups, meaning they had poorer endothelial function than controls.
Dr Mincu said: "Patients should realise that behind snoring there can be a serious cardiac pathology and they should get referred to a sleep specialist. If they are diagnosed with obstructive sleep apnea, they are at increased risk of cardiovascular disease and need to adopt a heart healthy lifestyle to reduce that risk."
She added: "Although OSA treatment with continuous positive airway pressure (CPAP) is inconvenient – it requires sleeping with a mask – patients should use it because it can reverse the parameters measured in our study."
Dr Mincu concluded: "Our study is a signal for cardiologists, pneumologists and general practitioners to work together to actively diagnose obstructive sleep apnea, administer the appropriate treatment (CPAP) and assess arterial function. This will help avoid progression of early cardiovascular dysfunction through to heart failure, the final stage of heart disease."
Notes to editor1 Obstructive sleep apnea determines endothelial dysfunction and increased arterial stiffness, similarly with diabetes mellitus (abstract 50318)
3 About the European Society of Cardiology (ESC)
The European Society of Cardiology (ESC) represents more than 75,000 cardiology professionals across Europe and the Mediterranean. Its mission is to reduce the burden of cardiovascular disease in Europe.Information for journalists attending EUROECHO and other Imaging Modalities 2012
Registration is possible onsite, with a valid press card, assignment letter or three bylined articles and signed Embargo form.
A press working area will be available on the exhibition lower level (Level -1). Follow the Speakers Service Centre/Press Working Area signage. There will be no press conference, but a press kit will be available and a press coordinator onsite will assist the media with any EUROECHO and other Imaging Modalities 2012 spokespersons enquiries.
Authors:ESC Press Office
ESC Press Office | EurekAlert!
Further reports about: > Association > CPAP > Cardiology > EACVI > ESC > Modalities > arterial stiffness > cardiovascular disease > cardiovascular dysfunction > cardiovascular risk factor > endothelial dysfunction > heart failure > obstructive sleep apnea > risk factor > vascular disease > vascular dysfunction
The genes are not to blame
20.07.2018 | Technische Universität München
Targeting headaches and tumors with nano-submarines
20.07.2018 | Universitätsmedizin der Johannes Gutenberg-Universität Mainz
A new manufacturing technique uses a process similar to newspaper printing to form smoother and more flexible metals for making ultrafast electronic devices.
The low-cost process, developed by Purdue University researchers, combines tools already used in industry for manufacturing metals on a large scale, but uses...
For the first time ever, scientists have determined the cosmic origin of highest-energy neutrinos. A research group led by IceCube scientist Elisa Resconi, spokesperson of the Collaborative Research Center SFB1258 at the Technical University of Munich (TUM), provides an important piece of evidence that the particles detected by the IceCube neutrino telescope at the South Pole originate from a galaxy four billion light-years away from Earth.
To rule out other origins with certainty, the team led by neutrino physicist Elisa Resconi from the Technical University of Munich and multi-wavelength...
For the first time a team of researchers have discovered two different phases of magnetic skyrmions in a single material. Physicists of the Technical Universities of Munich and Dresden and the University of Cologne can now better study and understand the properties of these magnetic structures, which are important for both basic research and applications.
Whirlpools are an everyday experience in a bath tub: When the water is drained a circular vortex is formed. Typically, such whirls are rather stable. Similar...
Physicists working with Roland Wester at the University of Innsbruck have investigated if and how chemical reactions can be influenced by targeted vibrational excitation of the reactants. They were able to demonstrate that excitation with a laser beam does not affect the efficiency of a chemical exchange reaction and that the excited molecular group acts only as a spectator in the reaction.
A frequently used reaction in organic chemistry is nucleophilic substitution. It plays, for example, an important role in in the synthesis of new chemical...
Optical spectroscopy allows investigating the energy structure and dynamic properties of complex quantum systems. Researchers from the University of Würzburg present two new approaches of coherent two-dimensional spectroscopy.
"Put an excitation into the system and observe how it evolves." According to physicist Professor Tobias Brixner, this is the credo of optical spectroscopy....
13.07.2018 | Event News
12.07.2018 | Event News
03.07.2018 | Event News
20.07.2018 | Power and Electrical Engineering
20.07.2018 | Information Technology
20.07.2018 | Materials Sciences