Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Trauma may alter the stress response, even in healthy people

22.11.2007
Researchers have known for years that psychological trauma that results in post-traumatic stress disorder (PTSD) or depression can change how a person responds to stress.

Now, Cornell researchers report that rapes, sudden deaths of loved ones, life-threatening accidents and other such traumas may result in long-term changes even if the survivor doesn't develop a clinical disorder.

"The findings suggest that there may be persistent differences in the stress response in some trauma-exposed people, even if they do not exhibit PTSD or depression or both, and even if their trauma was years in the past," said Barbara Ganzel, Cornell M.S. '99, Ph.D. '02, a lecturer in human development in Cornell's College of Human Ecology.

Ganzel led a team of Cornell researchers, whose study is published in a special issue of the Journal of Traumatic Stress on the biology of trauma. They assessed a group of women before and after they took their medical admissions tests (MCATs), a stressful experience for most people. Measuring levels of a stress hormone in saliva (cortisol), they found that women who had experienced trauma earlier in life (but who did not have PTSD or major depression) had lower levels cortisol leading up to and after the MCAT exam.

In addition, they found that the women who had experienced trauma kept a negative mood after the test, compared with other women, whose moods lifted significantly after the exams.

Ganzel suspects that the stress response system in these women have compensated or changed over time. The trauma-exposed women showed lower rather than higher levels of cortisol, Ganzel theorized, because "stress initially boosts cortisol output but after the stressor is over, cortisol falls below normal. These data suggest that, in some people, it may fall below normal and stay there, or that it develops a chronic tendency to dip lower than normal under stress."

The other co-authors are John Eckenrode, Pilyoung Kim, Elaine Wethington, all in human development at Cornell; Eric Horowitz '07; and Elise Temple, formerly of Cornell and now at Dartmouth College.

The research was supported by the College of Human Ecology, the Family Life Development Center and the Laboratory for Developmental Cognitive Neuroscience at Cornell, as well as by the National Institute of Mental Health.

Nicola Pytell | EurekAlert!
Further information:
http://www.cornell.edu

More articles from Health and Medicine:

nachricht Foods of the future
15.08.2018 | Georg-August-Universität Göttingen

nachricht New antibody analysis accelerates rational vaccine design
09.08.2018 | Scripps Research Institute

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Unraveling the nature of 'whistlers' from space in the lab

A new study sheds light on how ultralow frequency radio waves and plasmas interact

Scientists at the University of California, Los Angeles present new research on a curious cosmic phenomenon known as "whistlers" -- very low frequency packets...

Im Focus: New interactive machine learning tool makes car designs more aerodynamic

Scientists develop first tool to use machine learning methods to compute flow around interactively designable 3D objects. Tool will be presented at this year’s prestigious SIGGRAPH conference.

When engineers or designers want to test the aerodynamic properties of the newly designed shape of a car, airplane, or other object, they would normally model...

Im Focus: Robots as 'pump attendants': TU Graz develops robot-controlled rapid charging system for e-vehicles

Researchers from TU Graz and their industry partners have unveiled a world first: the prototype of a robot-controlled, high-speed combined charging system (CCS) for electric vehicles that enables series charging of cars in various parking positions.

Global demand for electric vehicles is forecast to rise sharply: by 2025, the number of new vehicle registrations is expected to reach 25 million per year....

Im Focus: The “TRiC” to folding actin

Proteins must be folded correctly to fulfill their molecular functions in cells. Molecular assistants called chaperones help proteins exploit their inbuilt folding potential and reach the correct three-dimensional structure. Researchers at the Max Planck Institute of Biochemistry (MPIB) have demonstrated that actin, the most abundant protein in higher developed cells, does not have the inbuilt potential to fold and instead requires special assistance to fold into its active state. The chaperone TRiC uses a previously undescribed mechanism to perform actin folding. The study was recently published in the journal Cell.

Actin is the most abundant protein in highly developed cells and has diverse functions in processes like cell stabilization, cell division and muscle...

Im Focus: Lining up surprising behaviors of superconductor with one of the world's strongest magnets

Scientists have discovered that the electrical resistance of a copper-oxide compound depends on the magnetic field in a very unusual way -- a finding that could help direct the search for materials that can perfectly conduct electricity at room temperatur

What happens when really powerful magnets--capable of producing magnetic fields nearly two million times stronger than Earth's--are applied to materials that...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

Within reach of the Universe

08.08.2018 | Event News

A journey through the history of microscopy – new exhibition opens at the MDC

27.07.2018 | Event News

2018 Work Research Conference

25.07.2018 | Event News

 
Latest News

Unraveling the nature of 'whistlers' from space in the lab

15.08.2018 | Physics and Astronomy

Diving robots find Antarctic winter seas exhale surprising amounts of carbon dioxide

15.08.2018 | Earth Sciences

Early opaque universe linked to galaxy scarcity

15.08.2018 | Physics and Astronomy

VideoLinks
Science & Research
Overview of more VideoLinks >>>