Monoclonal antibody targets key tumor growth factor; Successfully causes brain tumor regression and improves animal survival
Gliomas are the most common primary brain tumors, and also one of the most complicated cancers to treat. Currently, treatment options such as surgery, radiation and chemotherapy are only marginally beneficial and present significant risks for patients, including loss of physical and cognitive abilities. But, a new study published today in Clinical Cancer Research found that treatment with a novel monoclonal antibody (mAb) L2G7 inhibited the growth of glioma cells, induced glioma regression within the brain and prolonged survival – a finding that could be translated into human trials as early as next year.
"There is a tremendous need for advancement in the treatment of malignant brain tumors, which are the number one cancer killer of children under age 20 and a devastating diagnosis for adults as well," said Dr. John Laterra, M.D., Ph.D., research scientist at the Kennedy Krieger Institute and senior author of the study. "The results of this study bring us closer to developing an alternative treatment option for both adults and for pediatric patients, who are hardest hit by conventional therapies."
Study tracks inner workings of the brain with new biosensor
16.08.2018 | Rheinische Friedrich-Wilhelms-Universität Bonn
Foods of the future
15.08.2018 | Georg-August-Universität Göttingen
There are currently great hopes for solid-state batteries. They contain no liquid parts that could leak or catch fire. For this reason, they do not require cooling and are considered to be much safer, more reliable, and longer lasting than traditional lithium-ion batteries. Jülich scientists have now introduced a new concept that allows currents up to ten times greater during charging and discharging than previously described in the literature. The improvement was achieved by a “clever” choice of materials with a focus on consistently good compatibility. All components were made from phosphate compounds, which are well matched both chemically and mechanically.
The low current is considered one of the biggest hurdles in the development of solid-state batteries. It is the reason why the batteries take a relatively long...
New design tool automatically creates nanostructure 3D-print templates for user-given colors
Scientists present work at prestigious SIGGRAPH conference
Most of the objects we see are colored by pigments, but using pigments has disadvantages: such colors can fade, industrial pigments are often toxic, and...
Scientists at the University of California, Los Angeles present new research on a curious cosmic phenomenon known as "whistlers" -- very low frequency packets...
Scientists develop first tool to use machine learning methods to compute flow around interactively designable 3D objects. Tool will be presented at this year’s prestigious SIGGRAPH conference.
When engineers or designers want to test the aerodynamic properties of the newly designed shape of a car, airplane, or other object, they would normally model...
Researchers from TU Graz and their industry partners have unveiled a world first: the prototype of a robot-controlled, high-speed combined charging system (CCS) for electric vehicles that enables series charging of cars in various parking positions.
Global demand for electric vehicles is forecast to rise sharply: by 2025, the number of new vehicle registrations is expected to reach 25 million per year....
17.08.2018 | Event News
08.08.2018 | Event News
27.07.2018 | Event News
21.08.2018 | Ecology, The Environment and Conservation
21.08.2018 | Life Sciences
21.08.2018 | Power and Electrical Engineering