Engineers who have induced heart cells in culture to mimic the properties of the heart have used the tissue to gain new insight into the mechanisms that spawn irregular heart rhythms. Studies of the engineered cardiac tissue revealed that while electric shocks such as those delivered by defibrillators usually stopped aberrant waves, in some cases they cause them to accelerate and multiply.
The Duke University and Johns Hopkins University team, led by Nenad Bursac of Duke’s Pratt School of Engineering, reported its findings in the Feb. 1, 2006, Cardiovascular Research. Bursac and study co-author Leslie Tung conducted the experiments at Johns Hopkins before Bursac joined the Duke faculty. The work was supported by the National Institutes of Health and the American Heart Association.
In their experiments, the researchers sought to understand the characteristics of ventricular tachycardia -- a condition characterized by abnormally fast beating of the heart’s pumping chambers. In particular, they sought to understand how such arrhythmia may lead to ventricular fibrillation, in which the heart’s electrical activity becomes disordered, causing the ventricles to flutter rather than synchronously beat. As a result, pumping of the blood is inefficient, and death can result within minutes.
Kendall Morgan | EurekAlert!
The cytoskeleton of neurons has been found to be involved in Alzheimer's disease
18.01.2019 | University of the Basque Country
Bioinspired nanoscale drug delivery method developed by WSU, PNNL researchers
10.01.2019 | Washington State University
The scientific and political community alike stress the importance of German Antarctic research
Joint Press Release from the BMBF and AWI
The Antarctic is a frigid continent south of the Antarctic Circle, where researchers are the only inhabitants. Despite the hostile conditions, here the Alfred...
World first experiments on sensor that may revolutionise everything from medical devices to unmanned vehicles
The new sensor - capable of detecting vibrations of living cells - may revolutionise everything from medical devices to unmanned vehicles.
Dead and alive at the same time? Researchers at the Max Planck Institute of Quantum Optics have implemented Erwin Schrödinger’s paradoxical gedanken experiment employing an entangled atom-light state.
In 1935 Erwin Schrödinger formulated a thought experiment designed to capture the paradoxical nature of quantum physics. The crucial element of this gedanken...
Cellulose obtained from wood has amazing material properties. Empa researchers are now equipping the biodegradable material with additional functionalities to produce implants for cartilage diseases using 3D printing.
It all starts with an ear. Empa researcher Michael Hausmann removes the object shaped like a human ear from the 3D printer and explains:
The phenomenon of so-called superlubricity is known, but so far the explanation at the atomic level has been missing: for example, how does extremely low friction occur in bearings? Researchers from the Fraunhofer Institutes IWM and IWS jointly deciphered a universal mechanism of superlubricity for certain diamond-like carbon layers in combination with organic lubricants. Based on this knowledge, it is now possible to formulate design rules for supra lubricating layer-lubricant combinations. The results are presented in an article in Nature Communications, volume 10.
One of the most important prerequisites for sustainable and environmentally friendly mobility is minimizing friction. Research and industry have been dedicated...
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