Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Drug Delivery to the Lungs exhibition in Edinburgh

08.11.2005


A new optical instrument that could vastly reduce the amount of time the pharmaceutical industry spends in R&D, by speeding up the measurement of drug inhaler performance, is being launched by Loughborough University spin out VariDose Limited.



Heightened interest in innovative pulmonary drug delivery is fuelled by the emergence of inhaled systemic drugs and global concern over the sharp rise in respiratory conditions such as asthma and chronic obstructive pulmonary disease. The groundbreaking product, VariDose, utilises custom-designed and state of the art opto-electronics and takes less than 60 seconds to run each test.

It enables drug delivery and pharmaceutical companies to quickly, and more efficiently, test a wide range of drug-device combinations at the development stage, without relying on standard inhaler testing methods.


The VariDose device provides additional valuable information on the detailed characteristics of the particle or droplet cloud emitted by the inhaler and can also be positioned in-line with other measurement devices, a breathing simulator or a patient.

VariDose works by measuring the cloud of drug released from an inhaler as it passes through a tube intersected by co-planar beams of red, blue and infra-red light. Sensors are able to monitor the structure of the evolving drug cloud as the light passes through. Detailed analysis is then presented on a standard Windows® enabled PC or laptop. Results can be used to investigate essential cloud characteristics related to variability in particle size distribution, fine particle fraction and dose to pinpoint how design modifications could improve both drug and device effectiveness.

"Current measurement systems, such as cascade impactors and impingers, have been around for over 20 years and are inflexible and labour intensive. The use of VariDose during R&D will dramatically increase the efficiency of the development process," says Peter Smith, Professor of Photonics at Loughborough University and co-inventor, of VariDose, with Dr Olga Kusmartseva.

"VariDose represents a major step change in novel device and drug formulation research by enabling companies to focus on effective drugs and devices," adds Brian Barney, head of Drug Delivery at Cambridge Consultants - who developed the complete product in just four months. He continues, "I’m confident that in years to come the industry could look back at this product as a defining innovation in the development of drugs and delivery methods."

VariDose will be launched at the Drug Delivery to the Lungs exhibition and conference in Edinburgh on 7 - 9 December 2005.

Anna Seddon | alfa
Further information:
http://www.lboro.ac.uk

More articles from Health and Medicine:

nachricht Collagen nanofibrils in mammalian tissues get stronger with exercise
14.12.2018 | University of Illinois College of Engineering

nachricht New discoveries predict ability to forecast dementia from single molecule
12.12.2018 | UT Southwestern Medical Center

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Data storage using individual molecules

Researchers from the University of Basel have reported a new method that allows the physical state of just a few atoms or molecules within a network to be controlled. It is based on the spontaneous self-organization of molecules into extensive networks with pores about one nanometer in size. In the journal ‘small’, the physicists reported on their investigations, which could be of particular importance for the development of new storage devices.

Around the world, researchers are attempting to shrink data storage devices to achieve as large a storage capacity in as small a space as possible. In almost...

Im Focus: Data use draining your battery? Tiny device to speed up memory while also saving power

The more objects we make "smart," from watches to entire buildings, the greater the need for these devices to store and retrieve massive amounts of data quickly without consuming too much power.

Millions of new memory cells could be part of a computer chip and provide that speed and energy savings, thanks to the discovery of a previously unobserved...

Im Focus: An energy-efficient way to stay warm: Sew high-tech heating patches to your clothes

Personal patches could reduce energy waste in buildings, Rutgers-led study says

What if, instead of turning up the thermostat, you could warm up with high-tech, flexible patches sewn into your clothes - while significantly reducing your...

Im Focus: Lethal combination: Drug cocktail turns off the juice to cancer cells

A widely used diabetes medication combined with an antihypertensive drug specifically inhibits tumor growth – this was discovered by researchers from the University of Basel’s Biozentrum two years ago. In a follow-up study, recently published in “Cell Reports”, the scientists report that this drug cocktail induces cancer cell death by switching off their energy supply.

The widely used anti-diabetes drug metformin not only reduces blood sugar but also has an anti-cancer effect. However, the metformin dose commonly used in the...

Im Focus: New Foldable Drone Flies through Narrow Holes in Rescue Missions

A research team from the University of Zurich has developed a new drone that can retract its propeller arms in flight and make itself small to fit through narrow gaps and holes. This is particularly useful when searching for victims of natural disasters.

Inspecting a damaged building after an earthquake or during a fire is exactly the kind of job that human rescuers would like drones to do for them. A flying...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

ICTM Conference 2019: Digitization emerges as an engineering trend for turbomachinery construction

12.12.2018 | Event News

New Plastics Economy Investor Forum - Meeting Point for Innovations

10.12.2018 | Event News

EGU 2019 meeting: Media registration now open

06.12.2018 | Event News

 
Latest News

Pressure tuned magnetism paves the way for novel electronic devices

18.12.2018 | Materials Sciences

New type of low-energy nanolaser that shines in all directions

18.12.2018 | Physics and Astronomy

NASA research reveals Saturn is losing its rings at 'worst-case-scenario' rate

18.12.2018 | Physics and Astronomy

VideoLinks
Science & Research
Overview of more VideoLinks >>>