A study that includes 20 years of follow-up does not support aggressive treatment for localized, low-grade prostate cancer, with data indicating a small risk of progression of this grade of cancer, according to a study in the May 4 issue of JAMA.
To determine the need for treatment of localized prostate cancer, patients and physicians must understand the natural history of this disease, according to background information in the article. A recent study suggested an increasing prostate cancer death rate for men who are alive more than 15 years following diagnosis. The appropriate therapy for men with clinically localized prostate cancer has been uncertain.
Peter C. Albertsen, M.D., M.S., of the University of Connecticut Health Center, Farmington, Conn., and colleagues conducted a study to determine whether prostate cancer death rates declined, remained constant, or increased after 15 years. The researchers used data from the Connecticut Tumor Registry, supplemented by hospital record and histology review of 767 men aged 55 to 74 years with clinically localized prostate cancer diagnosed between January 1, 1971, and December 31, 1984. Patients were treated with either observation or immediate or delayed androgen withdrawal therapy, with an observation period of 24 years being the norm.
Carolyn Pennington | EurekAlert!
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Scientists at the University of California, Los Angeles present new research on a curious cosmic phenomenon known as "whistlers" -- very low frequency packets...
Scientists develop first tool to use machine learning methods to compute flow around interactively designable 3D objects. Tool will be presented at this year’s prestigious SIGGRAPH conference.
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Researchers from TU Graz and their industry partners have unveiled a world first: the prototype of a robot-controlled, high-speed combined charging system (CCS) for electric vehicles that enables series charging of cars in various parking positions.
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Proteins must be folded correctly to fulfill their molecular functions in cells. Molecular assistants called chaperones help proteins exploit their inbuilt folding potential and reach the correct three-dimensional structure. Researchers at the Max Planck Institute of Biochemistry (MPIB) have demonstrated that actin, the most abundant protein in higher developed cells, does not have the inbuilt potential to fold and instead requires special assistance to fold into its active state. The chaperone TRiC uses a previously undescribed mechanism to perform actin folding. The study was recently published in the journal Cell.
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Scientists have discovered that the electrical resistance of a copper-oxide compound depends on the magnetic field in a very unusual way -- a finding that could help direct the search for materials that can perfectly conduct electricity at room temperatur
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16.08.2018 | Life Sciences