Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

MRI Technique for Measuring Blood Volume Helps Distinguish Between Abscesses and Tumors in the Brain

09.11.2004


Dynamic susceptibility contrast (DSC) MRI allows physicians to differentiate between cerebral abscesses—inflamed areas in the brain caused by infection—and malignant brain tumors without surgery, says a new preliminary study by researchers from Duke University Medical Center in Durham, NC.



For the study, the researchers analyzed eight patients who underwent DSC MRI—four with cerebral abscesses and four with malignant brain tumors. DSC MRI is used to measure blood volume in brain tumors. Malignant brain tumors have high blood volume because they need new blood vessels in order to grow, while abscesses have the same blood volume as healthy tissue. On analyzing maps produced by DSC MRI of cerebral blood volume in these eight patients, the researchers found no overlap in the blood volume between the group of abscesses and the group of tumors .

According to the researchers, DSC MRI and traditional MRI are fundamentally different in the types of information they provide. “Regular MRI scans show the size and shape of a muscle or organ very well, but they don’t tell us much about how it is functioning. As we get more sophisticated in imaging organs, we want to know more than simply their size and the shape. DSC MRI gives us that additional necessary information, letting us know the vascular needs of the tissue ,” said James M. Provenzale, MD, one of the authors of the study.


Distinguishing between abscesses and tumors is a frequent problem for radiologists. “The distinction between abscess and tumor can be made by surgically removing tissue from the brain, but one would rather make the diagnosis by a noninvasive measure. The treatments for the two entities are also different: antibiotics for abscesses and surgical removal, chemotherapy or radiation therapy for tumors. A worst-case scenario would be one in which the wrong treatment is given for weeks or months due to a misdiagnosis,” said Dr. Provenzale.

The article appears in the November 2004 issue of the American Journal of Roentgenology.

Jason Ocker | EurekAlert!
Further information:
http://www.arrs.org

More articles from Health and Medicine:

nachricht New antibody analysis accelerates rational vaccine design
09.08.2018 | Scripps Research Institute

nachricht Distrust of power influences choice of medical procedures
01.08.2018 | Johannes Gutenberg-Universität Mainz

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: New interactive machine learning tool makes car designs more aerodynamic

Scientists develop first tool to use machine learning methods to compute flow around interactively designable 3D objects. Tool will be presented at this year’s prestigious SIGGRAPH conference.

When engineers or designers want to test the aerodynamic properties of the newly designed shape of a car, airplane, or other object, they would normally model...

Im Focus: Robots as 'pump attendants': TU Graz develops robot-controlled rapid charging system for e-vehicles

Researchers from TU Graz and their industry partners have unveiled a world first: the prototype of a robot-controlled, high-speed combined charging system (CCS) for electric vehicles that enables series charging of cars in various parking positions.

Global demand for electric vehicles is forecast to rise sharply: by 2025, the number of new vehicle registrations is expected to reach 25 million per year....

Im Focus: The “TRiC” to folding actin

Proteins must be folded correctly to fulfill their molecular functions in cells. Molecular assistants called chaperones help proteins exploit their inbuilt folding potential and reach the correct three-dimensional structure. Researchers at the Max Planck Institute of Biochemistry (MPIB) have demonstrated that actin, the most abundant protein in higher developed cells, does not have the inbuilt potential to fold and instead requires special assistance to fold into its active state. The chaperone TRiC uses a previously undescribed mechanism to perform actin folding. The study was recently published in the journal Cell.

Actin is the most abundant protein in highly developed cells and has diverse functions in processes like cell stabilization, cell division and muscle...

Im Focus: Lining up surprising behaviors of superconductor with one of the world's strongest magnets

Scientists have discovered that the electrical resistance of a copper-oxide compound depends on the magnetic field in a very unusual way -- a finding that could help direct the search for materials that can perfectly conduct electricity at room temperatur

What happens when really powerful magnets--capable of producing magnetic fields nearly two million times stronger than Earth's--are applied to materials that...

Im Focus: World record: Fastest 3-D tomographic images at BESSY II

The quality of materials often depends on the manufacturing process. In casting and welding, for example, the rate at which melts solidify and the resulting microstructure of the alloy is important. With metallic foams as well, it depends on exactly how the foaming process takes place. To understand these processes fully requires fast sensing capability. The fastest 3D tomographic images to date have now been achieved at the BESSY II X-ray source operated by the Helmholtz-Zentrum Berlin.

Dr. Francisco Garcia-Moreno and his team have designed a turntable that rotates ultra-stably about its axis at a constant rotational speed. This really depends...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

Within reach of the Universe

08.08.2018 | Event News

A journey through the history of microscopy – new exhibition opens at the MDC

27.07.2018 | Event News

2018 Work Research Conference

25.07.2018 | Event News

 
Latest News

'Building up' stretchable electronics to be as multipurpose as your smartphone

14.08.2018 | Information Technology

During HIV infection, antibody can block B cells from fighting pathogens

14.08.2018 | Life Sciences

First study on physical properties of giant cancer cells may inform new treatments

14.08.2018 | Life Sciences

VideoLinks
Science & Research
Overview of more VideoLinks >>>