It is more convenient to glue parts together than to suture them. Even surgeons agree to that. They only need a good adhesive. Siberian researchers have created the third generation bio-adhesive and successfully tested it on animals.
Surgery is steadily improving methods for joining of slit parts. To solve the problem, biological adhesives were recently used. More often physicians use chemical compounds based on alpha cyanoacrylates, which do not provoke allergy or stimulate tumorogenesis. The Novosibirsk researchers, specialists of the Central Administrative Board for Research Center of Clinical and Experimental Medicine (Siberian Branch, Russian Academy of Medical Sciences), Central Administrative Board for Scientific Research Institute of Regional Pathology and Pathomorphology (Siberian Branch, Russian Academy of Medical Sciences) and Novosibirsk State Medical Academy (Ministry of Public Health of the Russian Federation) have developed a new adhesive composition called “Sulfacrylate” and tested it in practice.
“Sulfacrylate” is bio-adhesive of the third generation, it includes various esters of acrylic acid and its derivatives. Experiments were carried out on 142 animals: rats, outbred cats and Chinchilla rabbits. Under anaesthetic, in line with all rules of operating skill, a part of animals’ liver, spleen, kindey or bowels was ablated and then the injured tissues were glued together. The background groups consisted of the animals which were sutured after the operation. The researchers were interested in the influence of bio-adhesive on the tissues in the course of cicatrization, therefore the operated animals were slaughtered 3, 6 and 12 hours, a day, a week and a month after the operation to investigate the tissue status under the microscope.
Sergey Komarov | alfa
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