Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Possible Brain Cancer-Air Pollution Link to Be Studied

02.10.2003

The Brain Tumor and Air Pollution Foundation today announced the beginning of a research project led by an internationally renowned neurosurgeon at Cedars-Sinai Medical Center to explore a possible link between brain cancer and air pollution.

The study will be led by Keith Black, M.D., director of the Cedars-Sinai Maxine Dunitz Neurosurgical Institute and Division of Neurosurgery in Los Angeles. The Brain Tumor foundation recently awarded $559,250 to the research project, with funding from the South Coast Air Quality Management District (AQMD).

The Cedars-Sinai investigation will examine biochemical and pathological changes in brain tissue of laboratory animals exposed to selected toxic air pollutants. These changes will be compared to those in human brain tumor tissue to determine whether air pollution causes changes in tissue associated with the formation of brain cancer.

Factors that led to the study include:

* Research documenting that certain toxic air pollutants are known to cause cancer in humans;
* An American Lung Association study that linked particulate pollution to lung cancer; and

* At least one investigation that found a dramatic increase of brain cancer rates in a metropolitan area, with a possible link to air pollution.

At today’s news conference, Dr. Black described the appearance of an increasing incidence in brain tumors in children and young people and noted that some estimates suggest brain cancers and other tumors of children’s nervous systems rose by more than 25 percent between 1973 and 1996.

"Brain cancer is the most common cause of cancer death in young people," Black said.

"Among the potentially toxic products of concern are the ultrafine particles that come from diesel engines - particles that would likely be plentiful along freeways, in congested metropolitan areas, and in the immediate vicinity of diesel-burning vehicles," Black said.

Ultrafine particles, including diesel soot and other combustion products, are those less than 0.1 micron in diameter (one micron is one millionth of one meter, or about 1/70th the diameter of a human hair). Such particles are able to lodge deep in human lungs and even enter the bloodstream due to their minute size.

"I believe the work we are initiating today will provide answers to important questions about brain cancer risk factors facing our children and future generations," Black concluded.

Los Angeles County Supervisor Michael D. Antonovich, also a member of the AQMD Governing Board as well as chairman of the Brain Tumor and Air Pollution Foundation, joined Dr. Black at today’s news conference.

"This study is consistent with AQMD’s mission because our agency is dedicated to protecting public health," Antonovich said.

"The state of California has established diesel particulate as a toxic and cancer-causing air pollutant.

"Now, we hope to determine whether brain tumors may be related to air pollution," Antonovich concluded.

In January, AQMD Governing Board Chairman William A. Burke proposed the creation of a Brain Tumor and Air Pollution Foundation. The following month, AQMD’s Board approved the establishment of the foundation. It has been chartered as a California non-profit public benefit corporation.

AQMD’s Board committed 10 percent of the agency’s air pollution penalty revenues from fiscal year 2002-03 -- about $722,500 -- to fund the foundation for one year. Of that amount, $559,250 will underwrite the research project led by Black.

The foundation hopes to use the remaining funds to support an additional epidemiology study of brain cancer and air pollution, comparing past trends of both phenomena.

The foundation’s Board of Directors include Supervisor Antonovich; Orange County Supervisor and AQMD Board Member James Silva; Hal Bernson, a former AQMD Board Member and former Los Angeles City Councilmember; and Robert Davidson, president and CEO of Los Angeles-based Surface Protection Industries.

Black is the leading expert on the blood-brain barrier and the delivery of chemotherapeutic drugs directly into tumors, holding patents for his method for selective opening of abnormal brain tissue capillaries. The blood-brain barrier refers to the boundary between blood vessels and brain tissue.

AQMD is the air pollution control agency for Orange County and major portions of Los Angeles, San Bernardino and Riverside counties

Sandy Van | Van Communications

More articles from Health and Medicine:

nachricht Correct antibiotic dosing could preserve lung microbial diversity in cystic fibrosis
22.02.2019 | Children's National Health System

nachricht Researchers find trigger that turns strep infections into flesh-eating disease
19.02.2019 | Houston Methodist

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: (Re)solving the jet/cocoon riddle of a gravitational wave event

An international research team including astronomers from the Max Planck Institute for Radio Astronomy in Bonn, Germany, has combined radio telescopes from five continents to prove the existence of a narrow stream of material, a so-called jet, emerging from the only gravitational wave event involving two neutron stars observed so far. With its high sensitivity and excellent performance, the 100-m radio telescope in Effelsberg played an important role in the observations.

In August 2017, two neutron stars were observed colliding, producing gravitational waves that were detected by the American LIGO and European Virgo detectors....

Im Focus: Light from a roll – hybrid OLED creates innovative and functional luminous surfaces

Up to now, OLEDs have been used exclusively as a novel lighting technology for use in luminaires and lamps. However, flexible organic technology can offer much more: as an active lighting surface, it can be combined with a wide variety of materials, not just to modify but to revolutionize the functionality and design of countless existing products. To exemplify this, the Fraunhofer FEP together with the company EMDE development of light GmbH will be presenting hybrid flexible OLEDs integrated into textile designs within the EU-funded project PI-SCALE for the first time at LOPEC (March 19-21, 2019 in Munich, Germany) as examples of some of the many possible applications.

The Fraunhofer FEP, a provider of research and development services in the field of organic electronics, has long been involved in the development of...

Im Focus: Regensburg physicists watch electron transfer in a single molecule

For the first time, an international team of scientists based in Regensburg, Germany, has recorded the orbitals of single molecules in different charge states in a novel type of microscopy. The research findings are published under the title “Mapping orbital changes upon electron transfer with tunneling microscopy on insulators” in the prestigious journal “Nature”.

The building blocks of matter surrounding us are atoms and molecules. The properties of that matter, however, are often not set by these building blocks...

Im Focus: University of Konstanz gains new insights into the recent development of the human immune system

Scientists at the University of Konstanz identify fierce competition between the human immune system and bacterial pathogens

Cell biologists from the University of Konstanz shed light on a recent evolutionary process in the human immune system and publish their findings in the...

Im Focus: Transformation through Light

Laser physicists have taken snapshots of carbon molecules C₆₀ showing how they transform in intense infrared light

When carbon molecules C₆₀ are exposed to an intense infrared light, they change their ball-like structure to a more elongated version. This has now been...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

Global Legal Hackathon at HAW Hamburg

11.02.2019 | Event News

The world of quantum chemistry meets in Heidelberg

30.01.2019 | Event News

Our digital society in 2040

16.01.2019 | Event News

 
Latest News

JILA researchers make coldest quantum gas of molecules

22.02.2019 | Physics and Astronomy

Understanding high efficiency of deep ultraviolet LEDs

22.02.2019 | Materials Sciences

Russian scientists show changes in the erythrocyte nanostructure under stress

22.02.2019 | Life Sciences

VideoLinks
Science & Research
Overview of more VideoLinks >>>