The reason that internal tumours are not treated with the method is that the technology does not exist to check that the precise amount of light is administered. However, software developed by researchers in atomic physics at Lund University in Sweden looks like being able to solve the problem.
“I think we are about to see a real breakthrough, both for us and for other research groups around the world who conduct research on cancer treatment using laser light”, says Johannes Swartling, Doctor of Atomic Physics at Lund University and Chief Technical Officer at SpectraCure, the company that is now developing the software.
The software’s unique feature is that it uses the optical fibres for more than simply emitting light. Intermittently they also gather information about the tumour, which they send back to the laser instrument.
“In this way, the software can continually calculate the optimal light dose and adjust it if necessary. The entire tumour must be removed, while damage to adjacent organs must be avoided”, says Johannes Swartling.
According to the researchers, the software could also be used with other light therapies that use LEDs or infra-red lasers.
Tests on prostate cancer patients in Sweden have shown that the method also works for internal tumours, and in the spring a clinical study on recurrent prostate cancer will begin in the US and Canada. An application for approval to carry out the study is pending. Meanwhile, the same laser light technology is being tested in the UK on pancreatic cancer.
“The advantage of laser light is that it appears that side effects can be minimised. With current treatment methods, prostate cancer patients who are cured risk both impotence and incontinence.”
In addition, traditional treatments entail a risk of cancer recurrence, says Johannes Swartling.
The international tests focus on adjusting dosage, guaranteeing safety and ensuring the effectiveness of treatment. If everything goes smoothly, SpectraCure hopes the method will be approved by the US Food and Drug Administration and Health Canada within a few years.
“This really could be revolutionary”, says Sune Svanberg, Professor of Laser Physics at Lund University and one of the researchers behind the technology.
“The new technology has great potential to help certain patient groups, for whom current treatment methods have major limitations”, says Professor Dr Katarina Svanberg, Department of Oncology, Lund University, who has been involved in the medical side of the development of the method.How photodynamic therapy works
The hardware and software are based on patents developed by atomic physicists in Lund, led by Sune Svanberg and Stefan Andersson-Engels. The idea was to allow the same optical fibres used for treatment to be used for diagnostic measurements that make it possible to calculate the light dose required. The method was soon seen to be practicable and has been developed over the years, now by SpectraCure. The implementation has been carried out by programmers.
For more information, please contact: Stefan Andersson-Engels, Professor of Atomic Physics, +46 46 222 3121, Stefan.Andersson-Engels@fysik.lth.se , Johannes Swartling, +46 708 233680, firstname.lastname@example.org or Jens Nilsen, CEO SpectraCure, +46 706 878712, email@example.com.
High resolution photographs of Stefan Andersson-Engels, Johannes Swartling and Sune Svanberg can be found in the Lund University image bank; enter the name required in the search field. Company photographs from Spectracure are also available; enter “Spectracure” in the search field.
Helga Ekdahl Heun | idw
Study tracks inner workings of the brain with new biosensor
16.08.2018 | Rheinische Friedrich-Wilhelms-Universität Bonn
Foods of the future
15.08.2018 | Georg-August-Universität Göttingen
New design tool automatically creates nanostructure 3D-print templates for user-given colors
Scientists present work at prestigious SIGGRAPH conference
Most of the objects we see are colored by pigments, but using pigments has disadvantages: such colors can fade, industrial pigments are often toxic, and...
Scientists at the University of California, Los Angeles present new research on a curious cosmic phenomenon known as "whistlers" -- very low frequency packets...
Scientists develop first tool to use machine learning methods to compute flow around interactively designable 3D objects. Tool will be presented at this year’s prestigious SIGGRAPH conference.
When engineers or designers want to test the aerodynamic properties of the newly designed shape of a car, airplane, or other object, they would normally model...
Researchers from TU Graz and their industry partners have unveiled a world first: the prototype of a robot-controlled, high-speed combined charging system (CCS) for electric vehicles that enables series charging of cars in various parking positions.
Global demand for electric vehicles is forecast to rise sharply: by 2025, the number of new vehicle registrations is expected to reach 25 million per year....
Proteins must be folded correctly to fulfill their molecular functions in cells. Molecular assistants called chaperones help proteins exploit their inbuilt folding potential and reach the correct three-dimensional structure. Researchers at the Max Planck Institute of Biochemistry (MPIB) have demonstrated that actin, the most abundant protein in higher developed cells, does not have the inbuilt potential to fold and instead requires special assistance to fold into its active state. The chaperone TRiC uses a previously undescribed mechanism to perform actin folding. The study was recently published in the journal Cell.
Actin is the most abundant protein in highly developed cells and has diverse functions in processes like cell stabilization, cell division and muscle...
17.08.2018 | Event News
08.08.2018 | Event News
27.07.2018 | Event News
17.08.2018 | Physics and Astronomy
17.08.2018 | Information Technology
17.08.2018 | Life Sciences