The reason that internal tumours are not treated with the method is that the technology does not exist to check that the precise amount of light is administered. However, software developed by researchers in atomic physics at Lund University in Sweden looks like being able to solve the problem.
“I think we are about to see a real breakthrough, both for us and for other research groups around the world who conduct research on cancer treatment using laser light”, says Johannes Swartling, Doctor of Atomic Physics at Lund University and Chief Technical Officer at SpectraCure, the company that is now developing the software.
The software’s unique feature is that it uses the optical fibres for more than simply emitting light. Intermittently they also gather information about the tumour, which they send back to the laser instrument.
“In this way, the software can continually calculate the optimal light dose and adjust it if necessary. The entire tumour must be removed, while damage to adjacent organs must be avoided”, says Johannes Swartling.
According to the researchers, the software could also be used with other light therapies that use LEDs or infra-red lasers.
Tests on prostate cancer patients in Sweden have shown that the method also works for internal tumours, and in the spring a clinical study on recurrent prostate cancer will begin in the US and Canada. An application for approval to carry out the study is pending. Meanwhile, the same laser light technology is being tested in the UK on pancreatic cancer.
“The advantage of laser light is that it appears that side effects can be minimised. With current treatment methods, prostate cancer patients who are cured risk both impotence and incontinence.”
In addition, traditional treatments entail a risk of cancer recurrence, says Johannes Swartling.
The international tests focus on adjusting dosage, guaranteeing safety and ensuring the effectiveness of treatment. If everything goes smoothly, SpectraCure hopes the method will be approved by the US Food and Drug Administration and Health Canada within a few years.
“This really could be revolutionary”, says Sune Svanberg, Professor of Laser Physics at Lund University and one of the researchers behind the technology.
“The new technology has great potential to help certain patient groups, for whom current treatment methods have major limitations”, says Professor Dr Katarina Svanberg, Department of Oncology, Lund University, who has been involved in the medical side of the development of the method.How photodynamic therapy works
The hardware and software are based on patents developed by atomic physicists in Lund, led by Sune Svanberg and Stefan Andersson-Engels. The idea was to allow the same optical fibres used for treatment to be used for diagnostic measurements that make it possible to calculate the light dose required. The method was soon seen to be practicable and has been developed over the years, now by SpectraCure. The implementation has been carried out by programmers.
For more information, please contact: Stefan Andersson-Engels, Professor of Atomic Physics, +46 46 222 3121, Stefan.Andersson-Engels@fysik.lth.se , Johannes Swartling, +46 708 233680, firstname.lastname@example.org or Jens Nilsen, CEO SpectraCure, +46 706 878712, email@example.com.
High resolution photographs of Stefan Andersson-Engels, Johannes Swartling and Sune Svanberg can be found in the Lund University image bank; enter the name required in the search field. Company photographs from Spectracure are also available; enter “Spectracure” in the search field.
Helga Ekdahl Heun | idw
Nitric oxide-scavenging hydrogel developed for rheumatoid arthritis treatment
06.06.2019 | Pohang University of Science & Technology (POSTECH)
Infants later diagnosed with autism follow adults’ gaze, but seldom initiate joint attention
24.05.2019 | Schwedischer Forschungsrat - The Swedish Research Council
Light can be used not only to measure materials’ properties, but also to change them. Especially interesting are those cases in which the function of a material can be modified, such as its ability to conduct electricity or to store information in its magnetic state. A team led by Andrea Cavalleri from the Max Planck Institute for the Structure and Dynamics of Matter in Hamburg used terahertz frequency light pulses to transform a non-ferroelectric material into a ferroelectric one.
Ferroelectricity is a state in which the constituent lattice “looks” in one specific direction, forming a macroscopic electrical polarisation. The ability to...
Researchers at TU Graz calculate the most accurate gravity field determination of the Earth using 1.16 billion satellite measurements. This yields valuable knowledge for climate research.
The Earth’s gravity fluctuates from place to place. Geodesists use this phenomenon to observe geodynamic and climatological processes. Using...
Discovery by Brazilian and US researchers could change the classification of two species, which appear more akin to jellyfish than was thought.
The tube anemone Isarachnanthus nocturnus is only 15 cm long but has the largest mitochondrial genome of any animal sequenced to date, with 80,923 base pairs....
Researchers at Chalmers University of Technology, Sweden, have discovered a completely new way of capturing, amplifying and linking light to matter at the nanolevel. Using a tiny box, built from stacked atomically thin material, they have succeeded in creating a type of feedback loop in which light and matter become one. The discovery, which was recently published in Nature Nanotechnology, opens up new possibilities in the world of nanophotonics.
Photonics is concerned with various means of using light. Fibre-optic communication is an example of photonics, as is the technology behind photodetectors and...
Fraunhofer IZM is joining the EUROPRACTICE IC Service platform. Together, the partners are making fan-out wafer level packaging (FOWLP) for electronic devices available and affordable even in small batches – and thus of interest to research institutes, universities, and SMEs. Costs can be significantly reduced by up to ten customers implementing individual fan-out wafer level packaging for their ICs or other components on a multi-project wafer. The target group includes any organization that does not produce in large quantities, but requires prototypes.
Research always means trying things out and daring to do new things. Research institutes, universities, and SMEs do not produce in large batches, but rather...
29.04.2019 | Event News
17.04.2019 | Event News
15.04.2019 | Event News
14.06.2019 | Information Technology
14.06.2019 | Materials Sciences
14.06.2019 | Medical Engineering