"People with diabetes are at risk for developing heart failure," says Henry Ford researcher and cardiologist David Lanfear, M.D., lead author of the study. "Diabetic adults die of heart disease two to four times more than those without diabetes.
"Our study data suggest that diabetic patients taking a particular class of medications are less likely to develop heart failure," adds Dr. Lanfear.
The results will be presented March 10 at the American College of Cardiology's annual meeting in San Francisco.
There are more than 25 million adults and children in the U.S. with diabetes, according to the American Diabetes Association. The ADA estimates that nearly 80 million people may be pre-diabetic, with nearly two million new cases diagnosed in adults in 2010. In 2007, diabetes contributed to a total of 231,404 deaths.
The retrospective study looked at 4,427 diabetic patients who were taking blood-sugar-lowering medications at Henry Ford Hospital between January 1, 2000 and July 1, 2012. Of these patients, 1,488 were taking GLP-1 medications (glucagon-like peptide-1 analogs and dipeptidyl peptidase-4 inhibitors) and 2,939 were not.
Over an observation time of 663 days, there were 281 hospitalizations, of which 184 were due to heart failure, and 158 deaths.
Results were adjusted for factors such as gender, age, race, coronary disease, heart failure, duration of diabetes, and the number of anti-diabetic medications, in order to identify the effect specifically attributable to taking GLP-1 medications. The researchers also looked at hospitalizations and deaths from all causes.
Use of GLP1 medications was associated with a reduced risk of hospitalization for heart failure or any other reason, as well as fewer deaths.
"These preliminary results look very promising," says Dr. Lanfear. "However this was a retrospective study and this subject needs further investigation."
The study was funded by the National Institutes of Health and Henry Ford Health System.
Sally Ann Brown | EurekAlert!
Purdue cancer identity technology makes it easier to find a tumor's 'address'
16.11.2018 | Purdue University
Microgel powder fights infection and helps wounds heal
14.11.2018 | Michigan Technological University
Researchers at the University of New Hampshire have captured a difficult-to-view singular event involving "magnetic reconnection"--the process by which sparse particles and energy around Earth collide producing a quick but mighty explosion--in the Earth's magnetotail, the magnetic environment that trails behind the planet.
Magnetic reconnection has remained a bit of a mystery to scientists. They know it exists and have documented the effects that the energy explosions can...
Biochips have been developed at TU Wien (Vienna), on which tissue can be produced and examined. This allows supplying the tissue with different substances in a very controlled way.
Cultivating human cells in the Petri dish is not a big challenge today. Producing artificial tissue, however, permeated by fine blood vessels, is a much more...
Faster and secure data communication: This is the goal of a new joint project involving physicists from the University of Würzburg. The German Federal Ministry of Education and Research funds the project with 14.8 million euro.
In our digital world data security and secure communication are becoming more and more important. Quantum communication is a promising approach to achieve...
On Saturday, 10 November 2018, the research icebreaker Polarstern will leave its homeport of Bremerhaven, bound for Cape Town, South Africa.
When choosing materials to make something, trade-offs need to be made between a host of properties, such as thickness, stiffness and weight. Depending on the application in question, finding just the right balance is the difference between success and failure
Now, a team of Penn Engineers has demonstrated a new material they call "nanocardboard," an ultrathin equivalent of corrugated paper cardboard. A square...
09.11.2018 | Event News
06.11.2018 | Event News
23.10.2018 | Event News
16.11.2018 | Health and Medicine
16.11.2018 | Life Sciences
16.11.2018 | Life Sciences