Researchers at Washington University School of Medicine in St. Louis have developed a new probe that allows them to watch protein activity in living cells. In their initial study, which focused on a protein tentatively linked to the spread of cancerous cells, the team both proved their new technique works and revealed surprising new details about the protein’s activity.
The protein in this study, neuronal Wiskott–Aldrich syndrome protein (N-WASP), is naturally found in every cell in the body and is known to be involved in a wide range of cellular processes. One of its key functions is believed to be guiding cellular growth and movement within the body, including when tumor cells metastasize, or spread, from one organ to another.
“To our knowledge this is the first probe of its kind that allows us to actually see in a living system where, when and how proteins are activated,” says first author Michael E. Ward, a graduate student in anatomy and neurobiology. “This is significant progress in moving from examining the biochemistry of ground up cells to being able to study it in an intact cell.”
Gila Z. Reckess | WUSTL
New study finds distinct microbes living next to corals
22.05.2019 | Woods Hole Oceanographic Institution
Summit charts a course to uncover the origins of genetic diseases
22.05.2019 | DOE/Oak Ridge National Laboratory
Engineers at the University of Tokyo continually pioneer new ways to improve battery technology. Professor Atsuo Yamada and his team recently developed a...
With a quantum coprocessor in the cloud, physicists from Innsbruck, Austria, open the door to the simulation of previously unsolvable problems in chemistry, materials research or high-energy physics. The research groups led by Rainer Blatt and Peter Zoller report in the journal Nature how they simulated particle physics phenomena on 20 quantum bits and how the quantum simulator self-verified the result for the first time.
Many scientists are currently working on investigating how quantum advantage can be exploited on hardware already available today. Three years ago, physicists...
'Quantum technologies' utilise the unique phenomena of quantum superposition and entanglement to encode and process information, with potentially profound benefits to a wide range of information technologies from communications to sensing and computing.
However a major challenge in developing these technologies is that the quantum phenomena are very fragile, and only a handful of physical systems have been...
Working group led by physicist Professor Ulrich Nowak at the University of Konstanz, in collaboration with a team of physicists from Johannes Gutenberg University Mainz, demonstrates how skyrmions can be used for the computer concepts of the future
When it comes to performing a calculation destined to arrive at an exact result, humans are hopelessly inferior to the computer. In other areas, humans are...
Scientists develop a molecular recording tool that enables in vivo lineage tracing of embryonic cells
The beginning of new life starts with a fascinating process: A single cell gives rise to progenitor cells that eventually differentiate into the three germ...
29.04.2019 | Event News
17.04.2019 | Event News
15.04.2019 | Event News
22.05.2019 | Life Sciences
22.05.2019 | Life Sciences
22.05.2019 | Physics and Astronomy