Researchers at Washington University School of Medicine in St. Louis have developed a new probe that allows them to watch protein activity in living cells. In their initial study, which focused on a protein tentatively linked to the spread of cancerous cells, the team both proved their new technique works and revealed surprising new details about the protein’s activity.
The protein in this study, neuronal Wiskott–Aldrich syndrome protein (N-WASP), is naturally found in every cell in the body and is known to be involved in a wide range of cellular processes. One of its key functions is believed to be guiding cellular growth and movement within the body, including when tumor cells metastasize, or spread, from one organ to another.
“To our knowledge this is the first probe of its kind that allows us to actually see in a living system where, when and how proteins are activated,” says first author Michael E. Ward, a graduate student in anatomy and neurobiology. “This is significant progress in moving from examining the biochemistry of ground up cells to being able to study it in an intact cell.”
Gila Z. Reckess | WUSTL
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There are currently great hopes for solid-state batteries. They contain no liquid parts that could leak or catch fire. For this reason, they do not require cooling and are considered to be much safer, more reliable, and longer lasting than traditional lithium-ion batteries. Jülich scientists have now introduced a new concept that allows currents up to ten times greater during charging and discharging than previously described in the literature. The improvement was achieved by a “clever” choice of materials with a focus on consistently good compatibility. All components were made from phosphate compounds, which are well matched both chemically and mechanically.
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New design tool automatically creates nanostructure 3D-print templates for user-given colors
Scientists present work at prestigious SIGGRAPH conference
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Scientists at the University of California, Los Angeles present new research on a curious cosmic phenomenon known as "whistlers" -- very low frequency packets...
Scientists develop first tool to use machine learning methods to compute flow around interactively designable 3D objects. Tool will be presented at this year’s prestigious SIGGRAPH conference.
When engineers or designers want to test the aerodynamic properties of the newly designed shape of a car, airplane, or other object, they would normally model...
Researchers from TU Graz and their industry partners have unveiled a world first: the prototype of a robot-controlled, high-speed combined charging system (CCS) for electric vehicles that enables series charging of cars in various parking positions.
Global demand for electric vehicles is forecast to rise sharply: by 2025, the number of new vehicle registrations is expected to reach 25 million per year....
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