In this way the sustained liberation of the vaccine or antigenic compound is assured, so that it remains active in the body of the animal over the period of at least six months”. The existing treatments possess a limited effect due to the necessity to constantly reapply the vaccine, a measure which will be unnecessary with this advance.
In addition, in her doctoral thesis, entitled “Micro- and nano-particles as helpers against brucellosis and ovine salmonella”, she developed a technique to maintain the effectiveness of existing products and avoid the denaturing and degradation which is suffered in the intestinal tract of sheep when vaccines are applied via the traditional oral method.
Infertility and mortality in sheep
This improvement in the treatment of brucellosis and ovine salmonella will mean an important advance in eliminating Brucella spp. and Salmonella Abortusovis, two bacteria which cause abortions in ovine livestock in Europe, as well as infertility in rams and mortality in lambs.
In addition, the researcher of the University of Navarra highlighted the utility of the vaccination as the most practical and economic means which can be applied in those zones where the disease is endemic, as is the case in Spain.
Irati Kortabitarte | alfa
Trees and climate change: Faster growth, lighter wood
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Proteins must be folded correctly to fulfill their molecular functions in cells. Molecular assistants called chaperones help proteins exploit their inbuilt folding potential and reach the correct three-dimensional structure. Researchers at the Max Planck Institute of Biochemistry (MPIB) have demonstrated that actin, the most abundant protein in higher developed cells, does not have the inbuilt potential to fold and instead requires special assistance to fold into its active state. The chaperone TRiC uses a previously undescribed mechanism to perform actin folding. The study was recently published in the journal Cell.
Actin is the most abundant protein in highly developed cells and has diverse functions in processes like cell stabilization, cell division and muscle...
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