Depression is common among opiate users and may serve as a trigger for high-risk drug injection practices, continued drug use, and relapse. Research has shown that individuals with co-occurring depression and substance use are less likely to complete treatment and have poorer prognoses after traditional treatment. However, scientists at the Brown University School of Medicine demonstrated that multisession, combination antidepressant therapy successfully reduced depression in active injection drug users.
Dr. Michael Stein and colleagues recruited 109 out-of-treatment injection drug users diagnosed with depression to participate in the study. Fifty-three participants received combined psychotherapy and pharmacotherapy for their depression during a 3-month period. These participants were scheduled to receive eight individual cognitive behavioral therapy (CBT) sessions and three pharmacotherapy visits. Fifty-six participants did not receive treatment. At the end of 3 months, adherence to treatment was assessed, and all study members participated in follow-up interviews designed to assess their heroin use and severity of depression.
Forty-three percent of participants receiving the combined treatment were considered to be fully adherent to their treatment schedules (receiving more than 75 percent of either psychotherapy or pharmacotherapy). At follow-up, significant reductions in depression were observed. Participants receiving the combined treatment were about 2.5 times more likely than those not receiving treatment to be in depression remission. Nearly 40 percent of participants who were fully adherent to treatment were in remission at 3 months, while only about 12 percent of those not receiving treatment were in remission at this time. Among all participants, depression status was associated with frequency of heroin use. Participants in remission at 3 months reported fewer than 8 days of heroin use during that time compared with roughly 13 days of heroin use among those not in remission.
Blair Gately | EurekAlert!
Fixating on faces
26.01.2017 | California Institute of Technology
Internet use in class tied to lower test scores
16.12.2016 | Michigan State University
Astronomers from Bonn and Tautenburg in Thuringia (Germany) used the 100-m radio telescope at Effelsberg to observe several galaxy clusters. At the edges of these large accumulations of dark matter, stellar systems (galaxies), hot gas, and charged particles, they found magnetic fields that are exceptionally ordered over distances of many million light years. This makes them the most extended magnetic fields in the universe known so far.
The results will be published on March 22 in the journal „Astronomy & Astrophysics“.
Galaxy clusters are the largest gravitationally bound structures in the universe. With a typical extent of about 10 million light years, i.e. 100 times the...
Researchers at the Goethe University Frankfurt, together with partners from the University of Tübingen in Germany and Queen Mary University as well as Francis Crick Institute from London (UK) have developed a novel technology to decipher the secret ubiquitin code.
Ubiquitin is a small protein that can be linked to other cellular proteins, thereby controlling and modulating their functions. The attachment occurs in many...
In the eternal search for next generation high-efficiency solar cells and LEDs, scientists at Los Alamos National Laboratory and their partners are creating...
Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are less stable. Now researchers at the Technical University of Munich (TUM) have, for the first time ever, produced a composite material combining silicon nanosheets and a polymer that is both UV-resistant and easy to process. This brings the scientists a significant step closer to industrial applications like flexible displays and photosensors.
Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are...
Enzymes behave differently in a test tube compared with the molecular scrum of a living cell. Chemists from the University of Basel have now been able to simulate these confined natural conditions in artificial vesicles for the first time. As reported in the academic journal Small, the results are offering better insight into the development of nanoreactors and artificial organelles.
Enzymes behave differently in a test tube compared with the molecular scrum of a living cell. Chemists from the University of Basel have now been able to...
20.03.2017 | Event News
14.03.2017 | Event News
07.03.2017 | Event News
22.03.2017 | Materials Sciences
22.03.2017 | Physics and Astronomy
22.03.2017 | Materials Sciences