“Structures built from a very large number of units can exhibit sharp transitions from one state to another state, which physicists call phase transitions,” said Cowan, a Professor in Mathematics and Neurology at Chicago. “Strange and interesting things happen in the neighborhood of a phase transition.”
When liquids undergo phase transitions, they evaporate into gas or freeze into ice. When the brain undergoes a phase transition, it moves from random to patterned activity. “The brain at rest produces random activity,” Cowan said, or what physicists call “Brownian motion.”
Although the bulk of his work involves deriving equations, Cowan’s findings mesh well with laboratory data generated on the cerebral cortex and electroencephalograms. His latest findings show that the same mathematical tools physicists use to describe the behavior of subatomic particles and the dynamics of liquids and solids can now be applied to understanding how the brain generates its various rhythms.
These include the delta waves generated during sleep, the alpha waves of the visual brain, and the gamma waves, discovered during the last decade, which seem related to information processing. “The resting state of brain activity seems to have a statistical structure that’s characteristic of a certain kind of phase transition,” Cowan said. “The brain likes to sit there because that’s the place where information processing is optimized.”
Cowan organized a session for AAAS on Mathematics and the Brain, which will take place from 8:30 to 10 a.m. EST Saturday, Feb. 16. He also will participate in a news briefing on the topic at 3 p.m. EST Friday, Feb. 15. Joining him at both events will be mathematician Nancy Kopell of Boston University and computational neuroscientist Tomaso Poggio of the Massachusetts Institute of Technology.
At this stage of his research, Cowan said it would be premature and speculative for him to try to relate how phase transitions in the brain might relate to neurological conditions or states of human consciousness. “That’s for the future,” he said.
Another component of his latest research is the close relationship between spontaneous pattern formation in brain circuits and in chemical reaction networks. In this research, he shows how mathematics can help explain visual hallucinations and how the visual cortex obtained its stripes, which are visible to the naked eye when removed from cadavers.
“This line of research on pattern formation can be traced back to Alan Turing, who also founded the modern science of computation,” said Terrence Sejnowski of the Salk Institute for Biological Studies in La Jolla, Calif., who is a leading specialist in computational neurobiology.
Cowan’s quest to understand the brain’s workings using numerical methods spans more than four decades. Along the way he has collaborated with a series of Ph.D. students and colleagues in physics, mathematics, biology and neuroscience.
In 1972, he and postdoctoral fellow Hugh Wilson, now of Canada’s York University, formulated a set of equations that could describe the dynamics of neural networks. Now called “Wilson-Cowan equations,” they became a mainstay of neural network research. “But I always knew that those equations were inadequate, so I kept thinking about them,” Cowan said.
Then in 1985, he ran across an article in a Japanese journal that described a statistical physics approach to chemical reaction networks. “It took me years to understand how to use these tools for biological networks,” he said. “It so happens that there is an analogy between the behavior of chemical reaction networks and neural networks.”
His research career began in 1962, when as a graduate student in electrical engineering, he worked with the founders of neural network theory. These included Norbert Wiener, who died in 1964, before they could work jointly on the problem that Cowan continues to address.
“I didn’t really understand what he was saying to me until I worked it out myself. He was one of the great mathematicians of the 20th century,” Cowan said.
Steve Koppes | EurekAlert!
Electrocatalysis can advance green transition
23.01.2017 | Technical University of Denmark
Quantum optical sensor for the first time tested in space – with a laser system from Berlin
23.01.2017 | Ferdinand-Braun-Institut Leibniz-Institut für Höchstfrequenztechnik
For the first time ever, a cloud of ultra-cold atoms has been successfully created in space on board of a sounding rocket. The MAIUS mission demonstrates that quantum optical sensors can be operated even in harsh environments like space – a prerequi-site for finding answers to the most challenging questions of fundamental physics and an important innovation driver for everyday applications.
According to Albert Einstein's Equivalence Principle, all bodies are accelerated at the same rate by the Earth's gravity, regardless of their properties. This...
An important step towards a completely new experimental access to quantum physics has been made at University of Konstanz. The team of scientists headed by...
Yersiniae cause severe intestinal infections. Studies using Yersinia pseudotuberculosis as a model organism aim to elucidate the infection mechanisms of these...
Researchers from the University of Hamburg in Germany, in collaboration with colleagues from the University of Aarhus in Denmark, have synthesized a new superconducting material by growing a few layers of an antiferromagnetic transition-metal chalcogenide on a bismuth-based topological insulator, both being non-superconducting materials.
While superconductivity and magnetism are generally believed to be mutually exclusive, surprisingly, in this new material, superconducting correlations...
Laser-driving of semimetals allows creating novel quasiparticle states within condensed matter systems and switching between different states on ultrafast time scales
Studying properties of fundamental particles in condensed matter systems is a promising approach to quantum field theory. Quasiparticles offer the opportunity...
19.01.2017 | Event News
10.01.2017 | Event News
09.01.2017 | Event News
23.01.2017 | Health and Medicine
23.01.2017 | Physics and Astronomy
23.01.2017 | Process Engineering