The paper is published in the April issue of "Archives of Ophthalmology," one of the JAMA/Archives journals.
Vitamin D status was assessed using the blood measure of 25-hydroxyvitamin D or 25 (OH) D. The 25 (OH) D level is generally considered the means by which nutritional vitamin D status is defined.
"In women younger than 75, those who had 25-hydroxyvitamin D concentrations lower than 38 nanomoles per liter were more likely to have age-related macular degeneration than women with concentrations greater than 38 nanomoles per liter," says Amy E. Millen, PhD, assistant professor in the UB School of Public Health and Health Professions and lead author. "Blood concentrations above 38 nanomoles per liter were associated with at least a 44 percent decreased odds of having AMD."
She notes that the Institute of Medicine considers an adult with a blood 25 hydroxyvitamin D concentration of lower than 30 nanomoles per liter to be at increased risk of vitamin D deficiency and a person with a concentration of less than 50 nanomoles per liter to be at increased risk for vitamin D inadequacy.
Millen's "Carotenoids in Age-Related Eye Disease Study (CAREDS)" involved data from 1,313 women. The purpose of the study was to investigate if serum 25 hydroxyvitamin D levels in the blood, the preferred biomarker for vitamin D, were associated with early age-related macular degeneration. CAREDS is an ancillary study within the Women's Health Initiative (WHI) Observational Study, which was conducted at WHI clinic centers in Oregon, Iowa and Wisconsin. UB is a major participating center in the WHI.
"The take- home message from this study is that having very low vitamin D status (25-hydroxyvitamin D blood concentrations lower than 38 nanomoles per liter) may be associated with increasing your odds of developing age-related macular degeneration," says Millen. "But based on these study findings, being at a higher vitamin D level than 38 nanomoles per liter does not appear to be more protective," she cautions.
Vitamin D status may be increased by spending moderate amounts of time outside, and eating foods rich in vitamin D, such as fatty fish from cold waters, and foods fortified with vitamin D, such as milk and fortified cereal, or by taking supplements.
"This is a promising study, but more still needs to be done," says Millen. "We still don't understand all of the effects of Vitamin D on health."
The research was funded by the NIH and by Research to Prevent Blindness.
The University at Buffalo is a premier research-intensive public university, a flagship institution in the State University of New York system and its largest and most comprehensive campus. UB's more than 28,000 students pursue their academic interests through more than 300 undergraduate, graduate and professional degree programs. Founded in 1846, the University at Buffalo is a member of the Association of American Universities.
Ellen Goldbaum | EurekAlert!
3D images of cancer cells in the body: Medical physicists from Halle present new method
16.05.2018 | Martin-Luther-Universität Halle-Wittenberg
Better equipped in the fight against lung cancer
16.05.2018 | Friedrich-Alexander-Universität Erlangen-Nürnberg
There are videos on the internet that can make one marvel at technology. For example, a smartphone is casually bent around the arm or a thin-film display is rolled in all directions and with almost every diameter. From the user's point of view, this looks fantastic. From a professional point of view, however, the question arises: Is that already possible?
At Display Week 2018, scientists from the Fraunhofer Institute for Applied Polymer Research IAP will be demonstrating today’s technological possibilities and...
So-called quantum many-body scars allow quantum systems to stay out of equilibrium much longer, explaining experiment | Study published in Nature Physics
Recently, researchers from Harvard and MIT succeeded in trapping a record 53 atoms and individually controlling their quantum state, realizing what is called a...
The historic first detection of gravitational waves from colliding black holes far outside our galaxy opened a new window to understanding the universe. A...
A team led by Austrian experimental physicist Rainer Blatt has succeeded in characterizing the quantum entanglement of two spatially separated atoms by observing their light emission. This fundamental demonstration could lead to the development of highly sensitive optical gradiometers for the precise measurement of the gravitational field or the earth's magnetic field.
The age of quantum technology has long been heralded. Decades of research into the quantum world have led to the development of methods that make it possible...
Cardiovascular tissue engineering aims to treat heart disease with prostheses that grow and regenerate. Now, researchers from the University of Zurich, the Technical University Eindhoven and the Charité Berlin have successfully implanted regenerative heart valves, designed with the aid of computer simulations, into sheep for the first time.
Producing living tissue or organs based on human cells is one of the main research fields in regenerative medicine. Tissue engineering, which involves growing...
02.05.2018 | Event News
13.04.2018 | Event News
12.04.2018 | Event News
22.05.2018 | Life Sciences
22.05.2018 | Life Sciences
22.05.2018 | Trade Fair News