Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Vitamin D deficiency linked to lung transplant rejection

19.10.2010
Loyola researchers evaluate impact of supplement on lung transplant outcomes

Vitamin D deficiency is associated with a significant increase in lung transplant rejection, according to research conducted at Loyola University Health System (LUHS). These data were presented Monday at The American Society for Bone and Mineral Research 2010 annual meeting in Toronto, Ontario.

"Vitamin D deficiency is prevalent among lung transplant recipients," said Pauline Camacho, MD, study investigator and director of the Loyola University Osteoporosis and Metabolic Bone Disease Center. "This study shed greater light on the serious impact that this deficiency has on lung transplant patients."

Patients who undergo lung transplants are at risk for rejecting the organ, and 77 percent of these patients are vitamin D deficient. Researchers believe that vitamin D helps the immune system tolerate the organ. Thus optimal levels of this supplement are critical for positive outcomes.

This study evaluated 122 patients who underwent a lung transplant at Loyola between January 2005 and June 2008. Sixty-four patients were male and 58 were female with an average age of 49.2 years. Vitamin D levels were checked following the transplants. Of the 122 patients, 50 percent were vitamin D deficient, 18 percent were not deficient and 32 percent were unknown. Vitamin D deficiency was associated with a significant increase in rejection for 51.7 percent of patients during the first year following transplant. Vitamin D deficiency also showed a trend toward increased airway inflammation in 16.7 percent of patients.

The health benefits of vitamin D are widespread and range from warding off cancer, osteoporosis, heart disease, diabetes and depression. Researchers speculate that vitamin D also may improve the health of lung transplant patients. Further studies will evaluate the effect of vitamin D therapy on short- and long-term lung transplant rejection rates, lung function and long-term survival.

Thomas Cascino, third-year medical student at Loyola University Chicago Stritch School of Medicine (Stritch); Charles Alex, MD, FCCP, program director for lung transplant at LUHS; and Ramon Durazo, PhD, assistant professor of preventive medicine and epidemiology at Stritch, also were study investigators.

For more information, visit www.loyolahealth.org

Follow Loyola on Facebook, Twitter and YouTube:

Facebook:
http://www.facebook.com/pages/Loyola-University-Health-System/108439715558
Twitter:
http://twitter.com/LoyolaHealth
YouTube:
http://www.youtube.com/user/LoyolaHealth#p/u

Nora Plunkett | EurekAlert!
Further information:
http://www.lumc.edu

More articles from Health and Medicine:

nachricht Norovirus evades immune system by hiding out in rare gut cells
12.10.2017 | University of Pennsylvania School of Medicine

nachricht Flexible sensors can detect movement in GI tract
11.10.2017 | Massachusetts Institute of Technology

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Neutron star merger directly observed for the first time

University of Maryland researchers contribute to historic detection of gravitational waves and light created by event

On August 17, 2017, at 12:41:04 UTC, scientists made the first direct observation of a merger between two neutron stars--the dense, collapsed cores that remain...

Im Focus: Breaking: the first light from two neutron stars merging

Seven new papers describe the first-ever detection of light from a gravitational wave source. The event, caused by two neutron stars colliding and merging together, was dubbed GW170817 because it sent ripples through space-time that reached Earth on 2017 August 17. Around the world, hundreds of excited astronomers mobilized quickly and were able to observe the event using numerous telescopes, providing a wealth of new data.

Previous detections of gravitational waves have all involved the merger of two black holes, a feat that won the 2017 Nobel Prize in Physics earlier this month....

Im Focus: Smart sensors for efficient processes

Material defects in end products can quickly result in failures in many areas of industry, and have a massive impact on the safe use of their products. This is why, in the field of quality assurance, intelligent, nondestructive sensor systems play a key role. They allow testing components and parts in a rapid and cost-efficient manner without destroying the actual product or changing its surface. Experts from the Fraunhofer IZFP in Saarbrücken will be presenting two exhibits at the Blechexpo in Stuttgart from 7–10 November 2017 that allow fast, reliable, and automated characterization of materials and detection of defects (Hall 5, Booth 5306).

When quality testing uses time-consuming destructive test methods, it can result in enormous costs due to damaging or destroying the products. And given that...

Im Focus: Cold molecules on collision course

Using a new cooling technique MPQ scientists succeed at observing collisions in a dense beam of cold and slow dipolar molecules.

How do chemical reactions proceed at extremely low temperatures? The answer requires the investigation of molecular samples that are cold, dense, and slow at...

Im Focus: Shrinking the proton again!

Scientists from the Max Planck Institute of Quantum Optics, using high precision laser spectroscopy of atomic hydrogen, confirm the surprisingly small value of the proton radius determined from muonic hydrogen.

It was one of the breakthroughs of the year 2010: Laser spectroscopy of muonic hydrogen resulted in a value for the proton charge radius that was significantly...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

ASEAN Member States discuss the future role of renewable energy

17.10.2017 | Event News

World Health Summit 2017: International experts set the course for the future of Global Health

10.10.2017 | Event News

Climate Engineering Conference 2017 Opens in Berlin

10.10.2017 | Event News

 
Latest News

Ocean atmosphere rife with microbes

17.10.2017 | Life Sciences

Neutrons observe vitamin B6-dependent enzyme activity useful for drug development

17.10.2017 | Life Sciences

NASA finds newly formed tropical storm lan over open waters

17.10.2017 | Earth Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>