But a review of these guidelines, published in the online open access journal, Arthritis Research & Therapy, found many differences in treatments addressed and a lack of educational information in most of the articles.
An international team of 13 clinical researchers, including rheumatologists, physiotherapists, occupational health experts and general practitioners, scrutinized six sets of knee osteoarthritis treatment guidelines, which were published or updated between 2001 and 2006. Evaluators were trained on how to apply the AGREE criteria to evaluate the guidelines.
Guidelines recommend acetaminophen for initial pain treatment, combined with exercise and education. If acetaminophen fails to control pain, NSAIDs are the next option, but should be used cautiously because of gastro-intestinal (GI) risks. The guidelines indicate surgery for persistent pain and disability. Most guidelines address education and activity management interventions superficially, and the team suggests that these should be detailed in the future.
The guideline effectively addressed only a minority of AGREE domains. “To improve applicability and increase uptake by end users, stakeholder opinions and barriers in use need to be taken into account during guideline development,” the authors say. Guideline development and the spreading of new knowledge are slow processes, and the authors also recommend development of innovative knowledge translation methods to health professionals.
Knee osteoarthritis causes significant costs and disability in the population, and is increasingly prevalent due to higher obesity rates and an aging population.
A review of the quality of knee osteoarthritis guidelines using the AGREE (Appraisal of Guidelines Research and Evaluation) instrument was published in 2002, and concluded that the quality of the guidelines varied and could generally be improved.
3D images of cancer cells in the body: Medical physicists from Halle present new method
16.05.2018 | Martin-Luther-Universität Halle-Wittenberg
Better equipped in the fight against lung cancer
16.05.2018 | Friedrich-Alexander-Universität Erlangen-Nürnberg
So-called quantum many-body scars allow quantum systems to stay out of equilibrium much longer, explaining experiment | Study published in Nature Physics
Recently, researchers from Harvard and MIT succeeded in trapping a record 53 atoms and individually controlling their quantum state, realizing what is called a...
The historic first detection of gravitational waves from colliding black holes far outside our galaxy opened a new window to understanding the universe. A...
A team led by Austrian experimental physicist Rainer Blatt has succeeded in characterizing the quantum entanglement of two spatially separated atoms by observing their light emission. This fundamental demonstration could lead to the development of highly sensitive optical gradiometers for the precise measurement of the gravitational field or the earth's magnetic field.
The age of quantum technology has long been heralded. Decades of research into the quantum world have led to the development of methods that make it possible...
Cardiovascular tissue engineering aims to treat heart disease with prostheses that grow and regenerate. Now, researchers from the University of Zurich, the Technical University Eindhoven and the Charité Berlin have successfully implanted regenerative heart valves, designed with the aid of computer simulations, into sheep for the first time.
Producing living tissue or organs based on human cells is one of the main research fields in regenerative medicine. Tissue engineering, which involves growing...
A team of scientists of the Max Planck Institute for the Structure and Dynamics of Matter (MPSD) at the Center for Free-Electron Laser Science in Hamburg investigated optically-induced superconductivity in the alkali-doped fulleride K3C60under high external pressures. This study allowed, on one hand, to uniquely assess the nature of the transient state as a superconducting phase. In addition, it unveiled the possibility to induce superconductivity in K3C60 at temperatures far above the -170 degrees Celsius hypothesized previously, and rather all the way to room temperature. The paper by Cantaluppi et al has been published in Nature Physics.
Unlike ordinary metals, superconductors have the unique capability of transporting electrical currents without any loss. Nowadays, their technological...
02.05.2018 | Event News
13.04.2018 | Event News
12.04.2018 | Event News
18.05.2018 | Power and Electrical Engineering
18.05.2018 | Information Technology
18.05.2018 | Information Technology