But a review of these guidelines, published in the online open access journal, Arthritis Research & Therapy, found many differences in treatments addressed and a lack of educational information in most of the articles.
An international team of 13 clinical researchers, including rheumatologists, physiotherapists, occupational health experts and general practitioners, scrutinized six sets of knee osteoarthritis treatment guidelines, which were published or updated between 2001 and 2006. Evaluators were trained on how to apply the AGREE criteria to evaluate the guidelines.
Guidelines recommend acetaminophen for initial pain treatment, combined with exercise and education. If acetaminophen fails to control pain, NSAIDs are the next option, but should be used cautiously because of gastro-intestinal (GI) risks. The guidelines indicate surgery for persistent pain and disability. Most guidelines address education and activity management interventions superficially, and the team suggests that these should be detailed in the future.
The guideline effectively addressed only a minority of AGREE domains. “To improve applicability and increase uptake by end users, stakeholder opinions and barriers in use need to be taken into account during guideline development,” the authors say. Guideline development and the spreading of new knowledge are slow processes, and the authors also recommend development of innovative knowledge translation methods to health professionals.
Knee osteoarthritis causes significant costs and disability in the population, and is increasingly prevalent due to higher obesity rates and an aging population.
A review of the quality of knee osteoarthritis guidelines using the AGREE (Appraisal of Guidelines Research and Evaluation) instrument was published in 2002, and concluded that the quality of the guidelines varied and could generally be improved.
Oxygen can wake up dormant bacteria for antibiotic attacks
08.12.2016 | Penn State
NTU scientists build new ultrasound device using 3-D printing technology
07.12.2016 | Nanyang Technological University
In recent years, lasers with ultrashort pulses (USP) down to the femtosecond range have become established on an industrial scale. They could advance some applications with the much-lauded “cold ablation” – if that meant they would then achieve more throughput. A new generation of process engineering that will address this issue in particular will be discussed at the “4th UKP Workshop – Ultrafast Laser Technology” in April 2017.
Even back in the 1990s, scientists were comparing materials processing with nanosecond, picosecond and femtosesecond pulses. The result was surprising:...
Have you ever wondered how you see the world? Vision is about photons of light, which are packets of energy, interacting with the atoms or molecules in what...
A multi-institutional research collaboration has created a novel approach for fabricating three-dimensional micro-optics through the shape-defined formation of porous silicon (PSi), with broad impacts in integrated optoelectronics, imaging, and photovoltaics.
Working with colleagues at Stanford and The Dow Chemical Company, researchers at the University of Illinois at Urbana-Champaign fabricated 3-D birefringent...
In experiments with magnetic atoms conducted at extremely low temperatures, scientists have demonstrated a unique phase of matter: The atoms form a new type of quantum liquid or quantum droplet state. These so called quantum droplets may preserve their form in absence of external confinement because of quantum effects. The joint team of experimental physicists from Innsbruck and theoretical physicists from Hannover report on their findings in the journal Physical Review X.
“Our Quantum droplets are in the gas phase but they still drop like a rock,” explains experimental physicist Francesca Ferlaino when talking about the...
The Max Planck Institute for Physics (MPP) is opening up a new research field. A workshop from November 21 - 22, 2016 will mark the start of activities for an innovative axion experiment. Axions are still only purely hypothetical particles. Their detection could solve two fundamental problems in particle physics: What dark matter consists of and why it has not yet been possible to directly observe a CP violation for the strong interaction.
The “MADMAX” project is the MPP’s commitment to axion research. Axions are so far only a theoretical prediction and are difficult to detect: on the one hand,...
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