Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Live kidney donors report high satisfaction rates and minimal health problems

28.11.2007
Live kidney donors suffer minimal health problems and 90 per cent would strongly encourage other people to a become a donor if a partner or family member needed a transplant, according to a study of more than 300 people published in the December issue of the UK-based urology journal BJU International.

Researchers from Egypt, where live donations are currently the only legal option, carried out detailed evaluations of 339 patients who attended follow-up clinics between January 2002 and January 2007.

Based at a centre which performs about 100 live donor transplants a year, they included patients who had donated kidneys between 1976 and the end of 2001 in their research.

“Living donors remain the main option in developing countries where donations from dead donors have yet to establish roots, because of the lack of infrastructure or the implementation of legal criteria for brain death” explains lead author Dr Amgad E El-Agroudy from the Urology and Nephrology Center at Mansoura University.

“Even in developing countries, the increasing demand for kidneys has resulted in a rapid increase in the number of living donors being used. This had led to concerns about the risk involved in the procedure and its long-term consequences.”

All of the people who took part in the study underwent an extensive physical and psychosocial assessment, which included a full range of laboratory tests and detailed medical history. Any medical problems were then compared with health tables for the general population.

The researchers found that the live donors studied had good kidney function and tended to suffer a lower incidence of high blood pressure, diabetes and heart-related deaths than the general Egyptian population.

However, the authors point out that donors have to have good general health, at the time of the transplant, including normal blood pressure, to even be considered for the procedure and this could account for some of the results.

90 per cent of the donors who took part in the study said that they would make the same decision again if a family member or partner needed a kidney and would strongly encourage others to become donors.

47 donors went on to have 65 babies between them, including 25 who had their first baby after surgery

1,200 kidney transplants using live donors are carried out in Egypt every year, where the incidence of end-stage kidney disease is 200 people in every million.

In the current study, almost two-third of the donors (62 per cent) were women and the sample included people who had donated five to thirty years ago, with an average gap of 11 years between surgery and follow-up.

37 per cent had donated a kidney to their child, 47 per cent to a brother or sister and 16 per cent to a spouse or partner.

60 per cent were working at the time of the donation and 67 per cent had a moderate financial income. No-one reported losing their job as the result of the surgery and only one person said it has put them at a financial disadvantage.

“Our conclusion is that living kidney donation is a safe procedure with minimal long-term complications” says Dr El-Agroudy. “Overall kidney function is well maintained after one kidney has been removed and donor satisfaction is consistent.

“It is important to point out that the donors were all partners, spouses or relatives of the patients they donated their kidney to and that they all underwent comprehensive medical screening before they were accepted onto our transplant programme.

“We believe that making sure that living kidney donors receive long-term follow-ups is very important and we would urge all transplant centres to establish programmes like ours to monitor their ongoing progress.”

“The authors have quite rightly identified a significant increase in live kidney donations in countries that also accept organ donations from deceased donors” says BJU International’s Editor, Professor John Fitzpatrick from University College Dublin, Ireland.

“In the UK for example, NHS figures state that live kidney donations now account for one in four kidney transplants in the UK and 690 were carried out in 2006-7, a 50 per cent increase on 2003-4.

“The Journal was keen to publish this study from a country that relies exclusively on living kidney donors as the authors had the opportunity to follow up a large number of transplants carried out between five and 30 years ago.”

Annette Whibley | alfa
Further information:
http://www.blackwellpublishing.com/BJU

More articles from Health and Medicine:

nachricht Penn vet research identifies new target for taming Ebola
12.01.2017 | University of Pennsylvania

nachricht The strange double life of Dab2
10.01.2017 | University of Miami Miller School of Medicine

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Interfacial Superconductivity: Magnetic and superconducting order revealed simultaneously

Researchers from the University of Hamburg in Germany, in collaboration with colleagues from the University of Aarhus in Denmark, have synthesized a new superconducting material by growing a few layers of an antiferromagnetic transition-metal chalcogenide on a bismuth-based topological insulator, both being non-superconducting materials.

While superconductivity and magnetism are generally believed to be mutually exclusive, surprisingly, in this new material, superconducting correlations...

Im Focus: Studying fundamental particles in materials

Laser-driving of semimetals allows creating novel quasiparticle states within condensed matter systems and switching between different states on ultrafast time scales

Studying properties of fundamental particles in condensed matter systems is a promising approach to quantum field theory. Quasiparticles offer the opportunity...

Im Focus: Designing Architecture with Solar Building Envelopes

Among the general public, solar thermal energy is currently associated with dark blue, rectangular collectors on building roofs. Technologies are needed for aesthetically high quality architecture which offer the architect more room for manoeuvre when it comes to low- and plus-energy buildings. With the “ArKol” project, researchers at Fraunhofer ISE together with partners are currently developing two façade collectors for solar thermal energy generation, which permit a high degree of design flexibility: a strip collector for opaque façade sections and a solar thermal blind for transparent sections. The current state of the two developments will be presented at the BAU 2017 trade fair.

As part of the “ArKol – development of architecturally highly integrated façade collectors with heat pipes” project, Fraunhofer ISE together with its partners...

Im Focus: How to inflate a hardened concrete shell with a weight of 80 t

At TU Wien, an alternative for resource intensive formwork for the construction of concrete domes was developed. It is now used in a test dome for the Austrian Federal Railways Infrastructure (ÖBB Infrastruktur).

Concrete shells are efficient structures, but not very resource efficient. The formwork for the construction of concrete domes alone requires a high amount of...

Im Focus: Bacterial Pac Man molecule snaps at sugar

Many pathogens use certain sugar compounds from their host to help conceal themselves against the immune system. Scientists at the University of Bonn have now, in cooperation with researchers at the University of York in the United Kingdom, analyzed the dynamics of a bacterial molecule that is involved in this process. They demonstrate that the protein grabs onto the sugar molecule with a Pac Man-like chewing motion and holds it until it can be used. Their results could help design therapeutics that could make the protein poorer at grabbing and holding and hence compromise the pathogen in the host. The study has now been published in “Biophysical Journal”.

The cells of the mouth, nose and intestinal mucosa produce large quantities of a chemical called sialic acid. Many bacteria possess a special transport system...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

12V, 48V, high-voltage – trends in E/E automotive architecture

10.01.2017 | Event News

2nd Conference on Non-Textual Information on 10 and 11 May 2017 in Hannover

09.01.2017 | Event News

Nothing will happen without batteries making it happen!

05.01.2017 | Event News

 
Latest News

Water - as the underlying driver of the Earth’s carbon cycle

17.01.2017 | Earth Sciences

Interfacial Superconductivity: Magnetic and superconducting order revealed simultaneously

17.01.2017 | Materials Sciences

Smart homes will “LISTEN” to your voice

17.01.2017 | Architecture and Construction

VideoLinks
B2B-VideoLinks
More VideoLinks >>>