Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Live kidney donors report high satisfaction rates and minimal health problems

28.11.2007
Live kidney donors suffer minimal health problems and 90 per cent would strongly encourage other people to a become a donor if a partner or family member needed a transplant, according to a study of more than 300 people published in the December issue of the UK-based urology journal BJU International.

Researchers from Egypt, where live donations are currently the only legal option, carried out detailed evaluations of 339 patients who attended follow-up clinics between January 2002 and January 2007.

Based at a centre which performs about 100 live donor transplants a year, they included patients who had donated kidneys between 1976 and the end of 2001 in their research.

“Living donors remain the main option in developing countries where donations from dead donors have yet to establish roots, because of the lack of infrastructure or the implementation of legal criteria for brain death” explains lead author Dr Amgad E El-Agroudy from the Urology and Nephrology Center at Mansoura University.

“Even in developing countries, the increasing demand for kidneys has resulted in a rapid increase in the number of living donors being used. This had led to concerns about the risk involved in the procedure and its long-term consequences.”

All of the people who took part in the study underwent an extensive physical and psychosocial assessment, which included a full range of laboratory tests and detailed medical history. Any medical problems were then compared with health tables for the general population.

The researchers found that the live donors studied had good kidney function and tended to suffer a lower incidence of high blood pressure, diabetes and heart-related deaths than the general Egyptian population.

However, the authors point out that donors have to have good general health, at the time of the transplant, including normal blood pressure, to even be considered for the procedure and this could account for some of the results.

90 per cent of the donors who took part in the study said that they would make the same decision again if a family member or partner needed a kidney and would strongly encourage others to become donors.

47 donors went on to have 65 babies between them, including 25 who had their first baby after surgery

1,200 kidney transplants using live donors are carried out in Egypt every year, where the incidence of end-stage kidney disease is 200 people in every million.

In the current study, almost two-third of the donors (62 per cent) were women and the sample included people who had donated five to thirty years ago, with an average gap of 11 years between surgery and follow-up.

37 per cent had donated a kidney to their child, 47 per cent to a brother or sister and 16 per cent to a spouse or partner.

60 per cent were working at the time of the donation and 67 per cent had a moderate financial income. No-one reported losing their job as the result of the surgery and only one person said it has put them at a financial disadvantage.

“Our conclusion is that living kidney donation is a safe procedure with minimal long-term complications” says Dr El-Agroudy. “Overall kidney function is well maintained after one kidney has been removed and donor satisfaction is consistent.

“It is important to point out that the donors were all partners, spouses or relatives of the patients they donated their kidney to and that they all underwent comprehensive medical screening before they were accepted onto our transplant programme.

“We believe that making sure that living kidney donors receive long-term follow-ups is very important and we would urge all transplant centres to establish programmes like ours to monitor their ongoing progress.”

“The authors have quite rightly identified a significant increase in live kidney donations in countries that also accept organ donations from deceased donors” says BJU International’s Editor, Professor John Fitzpatrick from University College Dublin, Ireland.

“In the UK for example, NHS figures state that live kidney donations now account for one in four kidney transplants in the UK and 690 were carried out in 2006-7, a 50 per cent increase on 2003-4.

“The Journal was keen to publish this study from a country that relies exclusively on living kidney donors as the authors had the opportunity to follow up a large number of transplants carried out between five and 30 years ago.”

Annette Whibley | alfa
Further information:
http://www.blackwellpublishing.com/BJU

More articles from Health and Medicine:

nachricht Penn study identifies new malaria parasites in wild bonobos
21.11.2017 | University of Pennsylvania School of Medicine

nachricht NIST scientists discover how to switch liver cancer cell growth from 2-D to 3-D structures
17.11.2017 | National Institute of Standards and Technology (NIST)

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Nanoparticles help with malaria diagnosis – new rapid test in development

The WHO reports an estimated 429,000 malaria deaths each year. The disease mostly affects tropical and subtropical regions and in particular the African continent. The Fraunhofer Institute for Silicate Research ISC teamed up with the Fraunhofer Institute for Molecular Biology and Applied Ecology IME and the Institute of Tropical Medicine at the University of Tübingen for a new test method to detect malaria parasites in blood. The idea of the research project “NanoFRET” is to develop a highly sensitive and reliable rapid diagnostic test so that patient treatment can begin as early as possible.

Malaria is caused by parasites transmitted by mosquito bite. The most dangerous form of malaria is malaria tropica. Left untreated, it is fatal in most cases....

Im Focus: A “cosmic snake” reveals the structure of remote galaxies

The formation of stars in distant galaxies is still largely unexplored. For the first time, astron-omers at the University of Geneva have now been able to closely observe a star system six billion light-years away. In doing so, they are confirming earlier simulations made by the University of Zurich. One special effect is made possible by the multiple reflections of images that run through the cosmos like a snake.

Today, astronomers have a pretty accurate idea of how stars were formed in the recent cosmic past. But do these laws also apply to older galaxies? For around a...

Im Focus: Visual intelligence is not the same as IQ

Just because someone is smart and well-motivated doesn't mean he or she can learn the visual skills needed to excel at tasks like matching fingerprints, interpreting medical X-rays, keeping track of aircraft on radar displays or forensic face matching.

That is the implication of a new study which shows for the first time that there is a broad range of differences in people's visual ability and that these...

Im Focus: Novel Nano-CT device creates high-resolution 3D-X-rays of tiny velvet worm legs

Computer Tomography (CT) is a standard procedure in hospitals, but so far, the technology has not been suitable for imaging extremely small objects. In PNAS, a team from the Technical University of Munich (TUM) describes a Nano-CT device that creates three-dimensional x-ray images at resolutions up to 100 nanometers. The first test application: Together with colleagues from the University of Kassel and Helmholtz-Zentrum Geesthacht the researchers analyzed the locomotory system of a velvet worm.

During a CT analysis, the object under investigation is x-rayed and a detector measures the respective amount of radiation absorbed from various angles....

Im Focus: Researchers Develop Data Bus for Quantum Computer

The quantum world is fragile; error correction codes are needed to protect the information stored in a quantum object from the deteriorating effects of noise. Quantum physicists in Innsbruck have developed a protocol to pass quantum information between differently encoded building blocks of a future quantum computer, such as processors and memories. Scientists may use this protocol in the future to build a data bus for quantum computers. The researchers have published their work in the journal Nature Communications.

Future quantum computers will be able to solve problems where conventional computers fail today. We are still far away from any large-scale implementation,...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Ecology Across Borders: International conference brings together 1,500 ecologists

15.11.2017 | Event News

Road into laboratory: Users discuss biaxial fatigue-testing for car and truck wheel

15.11.2017 | Event News

#Berlin5GWeek: The right network for Industry 4.0

30.10.2017 | Event News

 
Latest News

Researchers at IST Austria define function of an enigmatic synaptic protein

22.11.2017 | Life Sciences

Fine felted nanotubes: CAU research team develops new composite material made of carbon nanotubes

22.11.2017 | Materials Sciences

Women and lung cancer – the role of sex hormones

22.11.2017 | Life Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>