Two British scientists, Dr Ashley Croft and Dr Andrew Herxheimer, have published a paper which for the first time tries to explain the adverse effects of the controversial antimalaria drug, mefloquine (Lariam®).
Mefloquine, made by the Swiss drug company Hoffmann-La Roche, is used both to treat and prevent malaria. Since the 1980s doctors have used it to treat around 2 million people with malaria, and about 15 million travellers have used mefloquine as malaria prophylaxis.
Although many mefloquine users tolerate the drug well, in others it can cause a wide range of neuropsychiatric and other disturbing side effects, including hallucinations, nightmares, anxiety, tremor and psychosis. The first randomised controlled trial of mefloquine use in general travellers was published late last year in Clinical Infectious Diseases. One-third of the travellers using mefloquine reported neuropsychiatric adverse effects, and 6% of all mefloquine users reported at least one adverse event serious enough to require medical advice.
Andrew Herxheimer | alphagalileo
Satellites, airport visibility readings shed light on troops' exposure to air pollution
09.12.2016 | Veterans Affairs Research Communications
Oxygen can wake up dormant bacteria for antibiotic attacks
08.12.2016 | Penn State
Physicists of the University of Würzburg have made an astonishing discovery in a specific type of topological insulators. The effect is due to the structure of the materials used. The researchers have now published their work in the journal Science.
Topological insulators are currently the hot topic in physics according to the newspaper Neue Zürcher Zeitung. Only a few weeks ago, their importance was...
In recent years, lasers with ultrashort pulses (USP) down to the femtosecond range have become established on an industrial scale. They could advance some applications with the much-lauded “cold ablation” – if that meant they would then achieve more throughput. A new generation of process engineering that will address this issue in particular will be discussed at the “4th UKP Workshop – Ultrafast Laser Technology” in April 2017.
Even back in the 1990s, scientists were comparing materials processing with nanosecond, picosecond and femtosesecond pulses. The result was surprising:...
Have you ever wondered how you see the world? Vision is about photons of light, which are packets of energy, interacting with the atoms or molecules in what...
A multi-institutional research collaboration has created a novel approach for fabricating three-dimensional micro-optics through the shape-defined formation of porous silicon (PSi), with broad impacts in integrated optoelectronics, imaging, and photovoltaics.
Working with colleagues at Stanford and The Dow Chemical Company, researchers at the University of Illinois at Urbana-Champaign fabricated 3-D birefringent...
In experiments with magnetic atoms conducted at extremely low temperatures, scientists have demonstrated a unique phase of matter: The atoms form a new type of quantum liquid or quantum droplet state. These so called quantum droplets may preserve their form in absence of external confinement because of quantum effects. The joint team of experimental physicists from Innsbruck and theoretical physicists from Hannover report on their findings in the journal Physical Review X.
“Our Quantum droplets are in the gas phase but they still drop like a rock,” explains experimental physicist Francesca Ferlaino when talking about the...
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