Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

New Guidelines Set to Improve Standard of Cows’ Milk Allergy Care

21.09.2007
Only hypoallergenic formulas such as eHF and AAF suitable for children with CMA.

New guidelines on the diagnosis and management of cows’ milk allergy (CMA), published today in the Archives of Disease in Childhood, are set to improve the standard of care of infants with CMA, the most common food allergy in children.1

The Guidelines for the Diagnosis and Management of Cows’ Milk Protein Allergy recommend only extensively hydrolysed (eHF) and amino acid-based formulas (AAF), and the Taskforce’s recommendations warn against the risks of soy and other mammalian milks, such as sheep and goat, in CMA management.

Drawn up by the independent international Taskforce of allergy experts Act Against Allergy, and supported by an educational grant from SHS International, a leader in the field of specialised clinical nutrition, the guidelines offer clear recommendations on how to diagnose and manage CMA as well as two algorithms – one for breast-fed infants and one for formula-fed infants – addressing all levels of disease severity.

“These are the first practical guidelines on CMA diagnosis and management and are specifically aimed at primary care physicians and general paediatricians”, says Professor Yvan Vandenplas, Paediatric Gastroenterologist at Vrije Universiteit Brussel, Brussels, Belgium and Chair of the Act Against Allergy Taskforce. “Our recommendations will assist in establishing CMA diagnosis and level of severity, offering clear guidance on the recommended management at each stage, whilst debunking some of the misconceptions over the value of soy and other alternative milk sources in CMA.”

In their paper, the Taskforce recommends against the use of soy, especially in infants under six months old, due to the risk of secondary intolerance which can be present in up to 60% of CMA infants.2 Alternative mammalian milks, such as sheep, buffalo, horse, camel or goat, present an even higher risk of cross-reactivity and are not recommended at all in CMA. Furthermore, milk substitutes based on grains, legumes or nuts, such as rice, oat, pea or almond milk, are to be avoided in infants and young children due to their poor nutritional profile. According to the Act Against Allergy Guidelines, the only milk alternatives recommended for the effective management of CMA are specialised hypoallergenic CMA formulas, namely eHF’s and AAF’s.

AAF is the only formula type recommended for all degrees of CMA severity (i.e. mild, moderate and severe). These formulas are based on amino acids, the building blocks of protein, which are considered virtually incapable of provoking an allergic reaction,3 while providing optimal nutrition for of the infant. Immediate usage of AAF is also recommended in infants with suspected CMA showing failure to thrive – insufficient weight and/or length gain – in order to rapidly stabilise the infant’s physical development.

In cases of mild to moderate, but not severe, CMA, the Taskforce advises that an eHF may be sufficient. When milk proteins are broken down (hydrolysed) into smaller fragments – as happens in the production of eHF’s – their ability to provoke an allergic reaction is reduced. However, if symptoms do not improve sufficiently on an eHF, an AAF should be considered.

The SHS / Nutricia portfolio of hypoallergenic infant formulas is the only range of products that fully covers all degrees of CMA severity (i.e. mild to moderate and severe). The portfolio also includes the only AAF that is globally available and the most extensively clinically validated.

Jonathan Wogel, Global Allergy Director of SHS International says, “SHS International and Nutricia have a long-standing heritage in the development the medical nutrition field, with over two decades’ experience in the production of specialised CMA formulas. To date however, there has been confusion over the diagnosis and usage of cows’ milk alternatives. We are proud to have been able to support the Act Against Allergy Taskforce in this initiative in order to finally set a clear protocol on CMA management and improve the quality of lives of infants with cows’ milk allergy and their families across the world.”

References

1. Niggeman B, Binder C, Dupont C, et al. Prospective, controlled, multi-center study on the effect of an amino acid based formula in infants with cow’s milk allergy/intolerance and atopic dermatitis. Pediatr Allergy Immunol. 2001;12:78–82

2. American Academy of Pediatrics. Committee on Nutrition. Hypoallergenic Infant Formulas. Pediatr. 2000;106:346-349

3. Host A, Koletzko B et al. Dietary products used in infants for treatment and prevention of food allergy. Arch Dis Child. 1999: 81:80–84.

Claire Greeff | alfa
Further information:
http://adc.bmj.com/

More articles from Health and Medicine:

nachricht A promising target for kidney fibrosis
21.04.2017 | Brigham and Women's Hospital

nachricht Stem cell transplants: activating signal paths may protect from graft-versus-host disease
20.04.2017 | Technische Universität München

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Making lightweight construction suitable for series production

More and more automobile companies are focusing on body parts made of carbon fiber reinforced plastics (CFRP). However, manufacturing and repair costs must be further reduced in order to make CFRP more economical in use. Together with the Volkswagen AG and five other partners in the project HolQueSt 3D, the Laser Zentrum Hannover e.V. (LZH) has developed laser processes for the automatic trimming, drilling and repair of three-dimensional components.

Automated manufacturing processes are the basis for ultimately establishing the series production of CFRP components. In the project HolQueSt 3D, the LZH has...

Im Focus: Wonder material? Novel nanotube structure strengthens thin films for flexible electronics

Reflecting the structure of composites found in nature and the ancient world, researchers at the University of Illinois at Urbana-Champaign have synthesized thin carbon nanotube (CNT) textiles that exhibit both high electrical conductivity and a level of toughness that is about fifty times higher than copper films, currently used in electronics.

"The structural robustness of thin metal films has significant importance for the reliable operation of smart skin and flexible electronics including...

Im Focus: Deep inside Galaxy M87

The nearby, giant radio galaxy M87 hosts a supermassive black hole (BH) and is well-known for its bright jet dominating the spectrum over ten orders of magnitude in frequency. Due to its proximity, jet prominence, and the large black hole mass, M87 is the best laboratory for investigating the formation, acceleration, and collimation of relativistic jets. A research team led by Silke Britzen from the Max Planck Institute for Radio Astronomy in Bonn, Germany, has found strong indication for turbulent processes connecting the accretion disk and the jet of that galaxy providing insights into the longstanding problem of the origin of astrophysical jets.

Supermassive black holes form some of the most enigmatic phenomena in astrophysics. Their enormous energy output is supposed to be generated by the...

Im Focus: A Quantum Low Pass for Photons

Physicists in Garching observe novel quantum effect that limits the number of emitted photons.

The probability to find a certain number of photons inside a laser pulse usually corresponds to a classical distribution of independent events, the so-called...

Im Focus: Microprocessors based on a layer of just three atoms

Microprocessors based on atomically thin materials hold the promise of the evolution of traditional processors as well as new applications in the field of flexible electronics. Now, a TU Wien research team led by Thomas Müller has made a breakthrough in this field as part of an ongoing research project.

Two-dimensional materials, or 2D materials for short, are extremely versatile, although – or often more precisely because – they are made up of just one or a...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Expert meeting “Health Business Connect” will connect international medical technology companies

20.04.2017 | Event News

Wenn der Computer das Gehirn austrickst

18.04.2017 | Event News

7th International Conference on Crystalline Silicon Photovoltaics in Freiburg on April 3-5, 2017

03.04.2017 | Event News

 
Latest News

DGIST develops 20 times faster biosensor

24.04.2017 | Physics and Astronomy

Nanoimprinted hyperlens array: Paving the way for practical super-resolution imaging

24.04.2017 | Materials Sciences

Atomic-level motion may drive bacteria's ability to evade immune system defenses

24.04.2017 | Life Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>