Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Better treatment for children with brain cancer

23.07.2007
Young children diagnosed with a malignant type of brain tumour will benefit from research that has taken twelve years to complete.

In the search for better ways of treating children with brain cancer the study, carried out by the Children’s Cancer and Leukaemia Group at The University of Nottingham, revealed that a significant proportion of children under the age of three, with the brain tumour ependymoma, can be spared, or have delayed, the effects of radiotherapy by using chemotherapy — without compromising their chances of survival. The trial results were published in the Lancet Oncology on 20th July, 2007.

Experts in the field of childhood cancer recognise that radiotherapy can be harmful to a young child’s developing brain. It can affect IQ, short term memory, growth and puberty. The effective treatment of patients under the age of five remains, say the researchers, one of the more difficult tasks in paediatric oncology.

The trial was funded by Cancer Research UK and the Samantha Dickson Brain Tumour Trust. The study’s author, Professor Richard Grundy, from the Children’s Brain Tumour Research Centre (CBTRC), at The University of Nottingham said: “We know that radiotherapy can be harmful to the developing brain, so avoiding it, or using it at an older age if needed will hopefully reduce any learning difficulties these children may develop without compromising their chance of a cure”.

Every year over 450 children are diagnosed with a brain tumour in the UK. Established in 1997 the CBTRC is committed to developing new methods of research to help find a cure whilst minimising the risk of disability.

The survival rate for children diagnosed with ependymoma is getting better, but remains unacceptably low. Professor Grundy said: “It is now clear that if we are to improve the outcome for children with ependymoma we need a better understanding of the underlying biology of the disease.” Research fellows in Professor Grundy’s laboratory at the CBTRC are currently involved in a collaborative project with St Jude Children's Research Hospital in the USA and the Hospital for Sick Children to gain a better understanding of the biology of this disease in the hope of improving outcomes.

Emma Thorne | alfa
Further information:
http://www.nottingham.ac.uk

More articles from Health and Medicine:

nachricht Second cause of hidden hearing loss identified
20.02.2017 | Michigan Medicine - University of Michigan

nachricht Prospect for more effective treatment of nerve pain
20.02.2017 | Universität Zürich

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Breakthrough with a chain of gold atoms

In the field of nanoscience, an international team of physicists with participants from Konstanz has achieved a breakthrough in understanding heat transport

In the field of nanoscience, an international team of physicists with participants from Konstanz has achieved a breakthrough in understanding heat transport

Im Focus: DNA repair: a new letter in the cell alphabet

Results reveal how discoveries may be hidden in scientific “blind spots”

Cells need to repair damaged DNA in our genes to prevent the development of cancer and other diseases. Our cells therefore activate and send “repair-proteins”...

Im Focus: Dresdner scientists print tomorrow’s world

The Fraunhofer IWS Dresden and Technische Universität Dresden inaugurated their jointly operated Center for Additive Manufacturing Dresden (AMCD) with a festive ceremony on February 7, 2017. Scientists from various disciplines perform research on materials, additive manufacturing processes and innovative technologies, which build up components in a layer by layer process. This technology opens up new horizons for component design and combinations of functions. For example during fabrication, electrical conductors and sensors are already able to be additively manufactured into components. They provide information about stress conditions of a product during operation.

The 3D-printing technology, or additive manufacturing as it is often called, has long made the step out of scientific research laboratories into industrial...

Im Focus: Mimicking nature's cellular architectures via 3-D printing

Research offers new level of control over the structure of 3-D printed materials

Nature does amazing things with limited design materials. Grass, for example, can support its own weight, resist strong wind loads, and recover after being...

Im Focus: Three Magnetic States for Each Hole

Nanometer-scale magnetic perforated grids could create new possibilities for computing. Together with international colleagues, scientists from the Helmholtz Zentrum Dresden-Rossendorf (HZDR) have shown how a cobalt grid can be reliably programmed at room temperature. In addition they discovered that for every hole ("antidot") three magnetic states can be configured. The results have been published in the journal "Scientific Reports".

Physicist Dr. Rantej Bali from the HZDR, together with scientists from Singapore and Australia, designed a special grid structure in a thin layer of cobalt in...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Booth and panel discussion – The Lindau Nobel Laureate Meetings at the AAAS 2017 Annual Meeting

13.02.2017 | Event News

Complex Loading versus Hidden Reserves

10.02.2017 | Event News

International Conference on Crystal Growth in Freiburg

09.02.2017 | Event News

 
Latest News

Positrons as a new tool for lithium ion battery research: Holes in the electrode

22.02.2017 | Power and Electrical Engineering

New insights into the information processing of motor neurons

22.02.2017 | Life Sciences

Healthy Hiking in Smart Socks

22.02.2017 | Innovative Products

VideoLinks
B2B-VideoLinks
More VideoLinks >>>