Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Better treatment for children with brain cancer

23.07.2007
Young children diagnosed with a malignant type of brain tumour will benefit from research that has taken twelve years to complete.

In the search for better ways of treating children with brain cancer the study, carried out by the Children’s Cancer and Leukaemia Group at The University of Nottingham, revealed that a significant proportion of children under the age of three, with the brain tumour ependymoma, can be spared, or have delayed, the effects of radiotherapy by using chemotherapy — without compromising their chances of survival. The trial results were published in the Lancet Oncology on 20th July, 2007.

Experts in the field of childhood cancer recognise that radiotherapy can be harmful to a young child’s developing brain. It can affect IQ, short term memory, growth and puberty. The effective treatment of patients under the age of five remains, say the researchers, one of the more difficult tasks in paediatric oncology.

The trial was funded by Cancer Research UK and the Samantha Dickson Brain Tumour Trust. The study’s author, Professor Richard Grundy, from the Children’s Brain Tumour Research Centre (CBTRC), at The University of Nottingham said: “We know that radiotherapy can be harmful to the developing brain, so avoiding it, or using it at an older age if needed will hopefully reduce any learning difficulties these children may develop without compromising their chance of a cure”.

Every year over 450 children are diagnosed with a brain tumour in the UK. Established in 1997 the CBTRC is committed to developing new methods of research to help find a cure whilst minimising the risk of disability.

The survival rate for children diagnosed with ependymoma is getting better, but remains unacceptably low. Professor Grundy said: “It is now clear that if we are to improve the outcome for children with ependymoma we need a better understanding of the underlying biology of the disease.” Research fellows in Professor Grundy’s laboratory at the CBTRC are currently involved in a collaborative project with St Jude Children's Research Hospital in the USA and the Hospital for Sick Children to gain a better understanding of the biology of this disease in the hope of improving outcomes.

Emma Thorne | alfa
Further information:
http://www.nottingham.ac.uk

More articles from Health and Medicine:

nachricht A promising target for kidney fibrosis
21.04.2017 | Brigham and Women's Hospital

nachricht Stem cell transplants: activating signal paths may protect from graft-versus-host disease
20.04.2017 | Technische Universität München

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Deep inside Galaxy M87

The nearby, giant radio galaxy M87 hosts a supermassive black hole (BH) and is well-known for its bright jet dominating the spectrum over ten orders of magnitude in frequency. Due to its proximity, jet prominence, and the large black hole mass, M87 is the best laboratory for investigating the formation, acceleration, and collimation of relativistic jets. A research team led by Silke Britzen from the Max Planck Institute for Radio Astronomy in Bonn, Germany, has found strong indication for turbulent processes connecting the accretion disk and the jet of that galaxy providing insights into the longstanding problem of the origin of astrophysical jets.

Supermassive black holes form some of the most enigmatic phenomena in astrophysics. Their enormous energy output is supposed to be generated by the...

Im Focus: A Quantum Low Pass for Photons

Physicists in Garching observe novel quantum effect that limits the number of emitted photons.

The probability to find a certain number of photons inside a laser pulse usually corresponds to a classical distribution of independent events, the so-called...

Im Focus: Microprocessors based on a layer of just three atoms

Microprocessors based on atomically thin materials hold the promise of the evolution of traditional processors as well as new applications in the field of flexible electronics. Now, a TU Wien research team led by Thomas Müller has made a breakthrough in this field as part of an ongoing research project.

Two-dimensional materials, or 2D materials for short, are extremely versatile, although – or often more precisely because – they are made up of just one or a...

Im Focus: Quantum-physical Model System

Computer-assisted methods aid Heidelberg physicists in reproducing experiment with ultracold atoms

Two researchers at Heidelberg University have developed a model system that enables a better understanding of the processes in a quantum-physical experiment...

Im Focus: Glacier bacteria’s contribution to carbon cycling

Glaciers might seem rather inhospitable environments. However, they are home to a diverse and vibrant microbial community. It’s becoming increasingly clear that they play a bigger role in the carbon cycle than previously thought.

A new study, now published in the journal Nature Geoscience, shows how microbial communities in melting glaciers contribute to the Earth’s carbon cycle, a...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Expert meeting “Health Business Connect” will connect international medical technology companies

20.04.2017 | Event News

Wenn der Computer das Gehirn austrickst

18.04.2017 | Event News

7th International Conference on Crystalline Silicon Photovoltaics in Freiburg on April 3-5, 2017

03.04.2017 | Event News

 
Latest News

New quantum liquid crystals may play role in future of computers

21.04.2017 | Physics and Astronomy

A promising target for kidney fibrosis

21.04.2017 | Health and Medicine

Light rays from a supernova bent by the curvature of space-time around a galaxy

21.04.2017 | Physics and Astronomy

VideoLinks
B2B-VideoLinks
More VideoLinks >>>