Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Taking animals out of laboratory research

25.06.2007
Pioneering work to reduce the use of animals in scientific research — and ultimately remove them from laboratories altogether — has received a major boost at the University of Nottingham.

A laboratory devoted to finding effective alternatives to animal testing has been expanded and completely remodelled in a £240,000 overhaul designed to hasten the development of effective non-animal techniques.

Scientists hope that by developing the use of cell and tissue cultures, computer modelling, cell and molecular biology, epidemiology and other methods, they will one day be able to completely remove animals from medical research — while still maintaining crucial work to defeat diseases that affect millions of people.

The new FRAME Alternatives Laboratory, within the University’s Medical School, is to be officially opened by Ed Balls MP, Economic Secretary to the Treasury, on July 6.

FRAME – Fund for the Replacement of Animals in Medical Experiments — has had its laboratory at the University for 25 years, making Nottingham unique as the location of the charity’s only research facility. The lab is run as a FRAME/University collaboration.

FRAME advocates the use of alternative methods to animal testing, through the use of the ‘Three Rs’ — refinement, reduction and replacement. Refinement of procedures so that the suffering of any animals necessarily used is minimised, reduction of the number of animals used to an unavoidable minimum, and ultimately replacement of animals altogether with validated alternative methods such as cell cultures and computer modelling.

The charity is seeking reliable, scientifically proven ways forward which take account of the welfare of both humans and animals, without jeopardising the ground-breaking work on the major healthcare challenges of the 21st century taking place at research centres around the world.

The official opening of the new FRAME Alternatives Laboratory will be performed by Ed Balls MP at 11.30am on Friday, July 6. The event will also be attended by members of both FRAME and The University of Nottingham, who will be the guests of Professor Don Grierson, Pro-Vice-Chancellor for Research and for the Faculty of Medicine and Health Sciences.

Professor Terry Bennett, Head of the School of Biomedical Sciences, which houses the FRAME Alternatives Laboratory, said: “The close association between FRAME and the School of Biomedical Sciences in The University of Nottingham is clear evidence of the willingness of all concerned to take seriously the need for careful scrutiny of the use of animals in medical experiments, and the rigorous application of the principle of the ‘Three Rs’.”

Among the invited guests will be Brough Girling, husband of the late Julia Girling, who raised more than £12,000 for FRAME during her life and left a £100,000 legacy to the charity when she died last year. Their daughter Sarah will also attend. This legacy forms part of FRAME’s contribution to the remodelled laboratory. The overall cost of expanding and refurbishing the Laboratory has been shared equally between FRAME and the University.

Dr Nick Palmer, MP for Broxtowe and member of the FRAME all-party parliamentary group, will also attend the opening event.

Professor Michael Balls, Chairman of the Trustees of FRAME, said: “FRAME's decision to move from London to Nottingham in 1981, and to establish a research programme in collaboration with the University, was a master stroke, which greatly enhanced the standing of the Charity.

“The FRAME Alternatives Laboratory has deservedly earned an international reputation for its contributions to the development and validation of non-animal procedures to replace animal tests on chemicals and products of various kinds. The new facility will enable our work to reach out in new directions, so that we will be able to maintain our position at the forefront of research on alternatives to animal experimentation.”

Dr Andy Bennett, Director of the FRAME Alternatives Laboratory, said: “The new FRAME laboratories will provide a wonderful facility that will take our research into human cell culture-based alternatives forward.

“The positioning of the laboratory in the Medical School is highly beneficial and will allow us to further strengthen research links with clinicians and basic scientists at the University and the Nottingham University Hospitals NHS Trust.”

FRAME recognises that immediate abolition of all animal experiments is not possible, because vital medical research must continue to find treatments for diseases which lessen the quality of human and animal life. New consumer products, medicines, and industrial and agricultural chemicals must be adequately tested in order to identify potential hazards to human and animal health, and to the environment.

Boots plc contributed to the official opening on July 6, a further gesture of support for FRAME and its research programme, which has been given in various ways for more than 20 years.

Emma Thorne | alfa
Further information:
http://www.nottingham.ac.uk

More articles from Health and Medicine:

nachricht The end of pneumonia? New vaccine offers hope
23.10.2017 | University at Buffalo

nachricht Scientists track ovarian cancers to site of origin: Fallopian tubes
23.10.2017 | Johns Hopkins Medicine

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Salmonella as a tumour medication

HZI researchers developed a bacterial strain that can be used in cancer therapy

Salmonellae are dangerous pathogens that enter the body via contaminated food and can cause severe infections. But these bacteria are also known to target...

Im Focus: Neutron star merger directly observed for the first time

University of Maryland researchers contribute to historic detection of gravitational waves and light created by event

On August 17, 2017, at 12:41:04 UTC, scientists made the first direct observation of a merger between two neutron stars--the dense, collapsed cores that remain...

Im Focus: Breaking: the first light from two neutron stars merging

Seven new papers describe the first-ever detection of light from a gravitational wave source. The event, caused by two neutron stars colliding and merging together, was dubbed GW170817 because it sent ripples through space-time that reached Earth on 2017 August 17. Around the world, hundreds of excited astronomers mobilized quickly and were able to observe the event using numerous telescopes, providing a wealth of new data.

Previous detections of gravitational waves have all involved the merger of two black holes, a feat that won the 2017 Nobel Prize in Physics earlier this month....

Im Focus: Smart sensors for efficient processes

Material defects in end products can quickly result in failures in many areas of industry, and have a massive impact on the safe use of their products. This is why, in the field of quality assurance, intelligent, nondestructive sensor systems play a key role. They allow testing components and parts in a rapid and cost-efficient manner without destroying the actual product or changing its surface. Experts from the Fraunhofer IZFP in Saarbrücken will be presenting two exhibits at the Blechexpo in Stuttgart from 7–10 November 2017 that allow fast, reliable, and automated characterization of materials and detection of defects (Hall 5, Booth 5306).

When quality testing uses time-consuming destructive test methods, it can result in enormous costs due to damaging or destroying the products. And given that...

Im Focus: Cold molecules on collision course

Using a new cooling technique MPQ scientists succeed at observing collisions in a dense beam of cold and slow dipolar molecules.

How do chemical reactions proceed at extremely low temperatures? The answer requires the investigation of molecular samples that are cold, dense, and slow at...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

3rd Symposium on Driving Simulation

23.10.2017 | Event News

ASEAN Member States discuss the future role of renewable energy

17.10.2017 | Event News

World Health Summit 2017: International experts set the course for the future of Global Health

10.10.2017 | Event News

 
Latest News

Microfluidics probe 'cholesterol' of the oil industry

23.10.2017 | Life Sciences

Gamma rays will reach beyond the limits of light

23.10.2017 | Physics and Astronomy

The end of pneumonia? New vaccine offers hope

23.10.2017 | Health and Medicine

VideoLinks
B2B-VideoLinks
More VideoLinks >>>