Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Taking animals out of laboratory research

25.06.2007
Pioneering work to reduce the use of animals in scientific research — and ultimately remove them from laboratories altogether — has received a major boost at the University of Nottingham.

A laboratory devoted to finding effective alternatives to animal testing has been expanded and completely remodelled in a £240,000 overhaul designed to hasten the development of effective non-animal techniques.

Scientists hope that by developing the use of cell and tissue cultures, computer modelling, cell and molecular biology, epidemiology and other methods, they will one day be able to completely remove animals from medical research — while still maintaining crucial work to defeat diseases that affect millions of people.

The new FRAME Alternatives Laboratory, within the University’s Medical School, is to be officially opened by Ed Balls MP, Economic Secretary to the Treasury, on July 6.

FRAME – Fund for the Replacement of Animals in Medical Experiments — has had its laboratory at the University for 25 years, making Nottingham unique as the location of the charity’s only research facility. The lab is run as a FRAME/University collaboration.

FRAME advocates the use of alternative methods to animal testing, through the use of the ‘Three Rs’ — refinement, reduction and replacement. Refinement of procedures so that the suffering of any animals necessarily used is minimised, reduction of the number of animals used to an unavoidable minimum, and ultimately replacement of animals altogether with validated alternative methods such as cell cultures and computer modelling.

The charity is seeking reliable, scientifically proven ways forward which take account of the welfare of both humans and animals, without jeopardising the ground-breaking work on the major healthcare challenges of the 21st century taking place at research centres around the world.

The official opening of the new FRAME Alternatives Laboratory will be performed by Ed Balls MP at 11.30am on Friday, July 6. The event will also be attended by members of both FRAME and The University of Nottingham, who will be the guests of Professor Don Grierson, Pro-Vice-Chancellor for Research and for the Faculty of Medicine and Health Sciences.

Professor Terry Bennett, Head of the School of Biomedical Sciences, which houses the FRAME Alternatives Laboratory, said: “The close association between FRAME and the School of Biomedical Sciences in The University of Nottingham is clear evidence of the willingness of all concerned to take seriously the need for careful scrutiny of the use of animals in medical experiments, and the rigorous application of the principle of the ‘Three Rs’.”

Among the invited guests will be Brough Girling, husband of the late Julia Girling, who raised more than £12,000 for FRAME during her life and left a £100,000 legacy to the charity when she died last year. Their daughter Sarah will also attend. This legacy forms part of FRAME’s contribution to the remodelled laboratory. The overall cost of expanding and refurbishing the Laboratory has been shared equally between FRAME and the University.

Dr Nick Palmer, MP for Broxtowe and member of the FRAME all-party parliamentary group, will also attend the opening event.

Professor Michael Balls, Chairman of the Trustees of FRAME, said: “FRAME's decision to move from London to Nottingham in 1981, and to establish a research programme in collaboration with the University, was a master stroke, which greatly enhanced the standing of the Charity.

“The FRAME Alternatives Laboratory has deservedly earned an international reputation for its contributions to the development and validation of non-animal procedures to replace animal tests on chemicals and products of various kinds. The new facility will enable our work to reach out in new directions, so that we will be able to maintain our position at the forefront of research on alternatives to animal experimentation.”

Dr Andy Bennett, Director of the FRAME Alternatives Laboratory, said: “The new FRAME laboratories will provide a wonderful facility that will take our research into human cell culture-based alternatives forward.

“The positioning of the laboratory in the Medical School is highly beneficial and will allow us to further strengthen research links with clinicians and basic scientists at the University and the Nottingham University Hospitals NHS Trust.”

FRAME recognises that immediate abolition of all animal experiments is not possible, because vital medical research must continue to find treatments for diseases which lessen the quality of human and animal life. New consumer products, medicines, and industrial and agricultural chemicals must be adequately tested in order to identify potential hazards to human and animal health, and to the environment.

Boots plc contributed to the official opening on July 6, a further gesture of support for FRAME and its research programme, which has been given in various ways for more than 20 years.

Emma Thorne | alfa
Further information:
http://www.nottingham.ac.uk

More articles from Health and Medicine:

nachricht A promising target for kidney fibrosis
21.04.2017 | Brigham and Women's Hospital

nachricht Stem cell transplants: activating signal paths may protect from graft-versus-host disease
20.04.2017 | Technische Universität München

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Making lightweight construction suitable for series production

More and more automobile companies are focusing on body parts made of carbon fiber reinforced plastics (CFRP). However, manufacturing and repair costs must be further reduced in order to make CFRP more economical in use. Together with the Volkswagen AG and five other partners in the project HolQueSt 3D, the Laser Zentrum Hannover e.V. (LZH) has developed laser processes for the automatic trimming, drilling and repair of three-dimensional components.

Automated manufacturing processes are the basis for ultimately establishing the series production of CFRP components. In the project HolQueSt 3D, the LZH has...

Im Focus: Wonder material? Novel nanotube structure strengthens thin films for flexible electronics

Reflecting the structure of composites found in nature and the ancient world, researchers at the University of Illinois at Urbana-Champaign have synthesized thin carbon nanotube (CNT) textiles that exhibit both high electrical conductivity and a level of toughness that is about fifty times higher than copper films, currently used in electronics.

"The structural robustness of thin metal films has significant importance for the reliable operation of smart skin and flexible electronics including...

Im Focus: Deep inside Galaxy M87

The nearby, giant radio galaxy M87 hosts a supermassive black hole (BH) and is well-known for its bright jet dominating the spectrum over ten orders of magnitude in frequency. Due to its proximity, jet prominence, and the large black hole mass, M87 is the best laboratory for investigating the formation, acceleration, and collimation of relativistic jets. A research team led by Silke Britzen from the Max Planck Institute for Radio Astronomy in Bonn, Germany, has found strong indication for turbulent processes connecting the accretion disk and the jet of that galaxy providing insights into the longstanding problem of the origin of astrophysical jets.

Supermassive black holes form some of the most enigmatic phenomena in astrophysics. Their enormous energy output is supposed to be generated by the...

Im Focus: A Quantum Low Pass for Photons

Physicists in Garching observe novel quantum effect that limits the number of emitted photons.

The probability to find a certain number of photons inside a laser pulse usually corresponds to a classical distribution of independent events, the so-called...

Im Focus: Microprocessors based on a layer of just three atoms

Microprocessors based on atomically thin materials hold the promise of the evolution of traditional processors as well as new applications in the field of flexible electronics. Now, a TU Wien research team led by Thomas Müller has made a breakthrough in this field as part of an ongoing research project.

Two-dimensional materials, or 2D materials for short, are extremely versatile, although – or often more precisely because – they are made up of just one or a...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Expert meeting “Health Business Connect” will connect international medical technology companies

20.04.2017 | Event News

Wenn der Computer das Gehirn austrickst

18.04.2017 | Event News

7th International Conference on Crystalline Silicon Photovoltaics in Freiburg on April 3-5, 2017

03.04.2017 | Event News

 
Latest News

DGIST develops 20 times faster biosensor

24.04.2017 | Physics and Astronomy

Nanoimprinted hyperlens array: Paving the way for practical super-resolution imaging

24.04.2017 | Materials Sciences

Atomic-level motion may drive bacteria's ability to evade immune system defenses

24.04.2017 | Life Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>