Ana Azevedo and colleagues, from the University of Porto Medical School, Portugal, investigated the possibility of a graded association between the number of features of metabolic syndrome and cardiac structural and functional abnormalities. Their study also investigated whether the associations found were independent of coronary heart disease risk as predicted by the Framingham risk score, a standard tool to predict the probability of having heart disease in the future.
The authors investigated a sample of urban Portuguese adults who were invited to a full screening interview including questionnaires, blood tests for cholesterol and glucose levels, and an ECG measurement. This was followed up with a structured clinical interview including a cardiovascular physical examination, transthoracic echocardiogram and pulsed Doppler evaluation. The results indicated that symptomatic heart failure and severe cardiac structural and functional abnormalities rise progressively with increasing degree of metabolic syndrome, regardless of symptoms. This association was independent of the 10-year predicted risk of coronary heart disease by Framingham risk score for indirect indices of diastolic dysfunction, but not systolic dysfunction.
Unlike in previous studies, the association between metabolic syndrome and heart disease found in this research is not fully explained by blood pressure levels, the authors suggest. “Metabolic syndrome may help predict an increased cardiovascular risk beyond that predicted by the more frequently used Framingham risk score,” Azevedo says.
Routing gene therapy directly into the brain
07.12.2017 | Boston Children's Hospital
New Hope for Cancer Therapies: Targeted Monitoring may help Improve Tumor Treatment
01.12.2017 | Berliner Institut für Gesundheitsforschung / Berlin Institute of Health (BIH)
Researchers have developed a water cloaking concept based on electromagnetic forces that could eliminate an object's wake, greatly reducing its drag while...
Tiny pores at a cell's entryway act as miniature bouncers, letting in some electrically charged atoms--ions--but blocking others. Operating as exquisitely sensitive filters, these "ion channels" play a critical role in biological functions such as muscle contraction and the firing of brain cells.
To rapidly transport the right ions through the cell membrane, the tiny channels rely on a complex interplay between the ions and surrounding molecules,...
The miniaturization of the current technology of storage media is hindered by fundamental limits of quantum mechanics. A new approach consists in using so-called spin-crossover molecules as the smallest possible storage unit. Similar to normal hard drives, these special molecules can save information via their magnetic state. A research team from Kiel University has now managed to successfully place a new class of spin-crossover molecules onto a surface and to improve the molecule’s storage capacity. The storage density of conventional hard drives could therefore theoretically be increased by more than one hundred fold. The study has been published in the scientific journal Nano Letters.
Over the past few years, the building blocks of storage media have gotten ever smaller. But further miniaturization of the current technology is hindered by...
With innovative experiments, researchers at the Helmholtz-Zentrums Geesthacht and the Technical University Hamburg unravel why tiny metallic structures are extremely strong
Light-weight and simultaneously strong – porous metallic nanomaterials promise interesting applications as, for instance, for future aeroplanes with enhanced...
An interdisciplinary group of researchers interfaced individual bacteria with a computer to build a hybrid bio-digital circuit - Study published in Nature Communications
Scientists at the Institute of Science and Technology Austria (IST Austria) have managed to control the behavior of individual bacteria by connecting them to a...
11.12.2017 | Event News
08.12.2017 | Event News
07.12.2017 | Event News
12.12.2017 | Earth Sciences
12.12.2017 | Power and Electrical Engineering
12.12.2017 | Life Sciences