Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Treatment of kidney condition requires an individualised approach

15.05.2007
Good patient information is essential for choosing the best treatment for the kidney disease lupus nephritis. Dutch researcher Cecile Grootscholten concludes this following her doctoral research into two methods for treating lupus nephritis. She did not demonstrate any major differences but both treatments have pros and cons.

The severity of the kidney disease lupus nephritis varies and the side effects of the treatments differ as well. Therefore Grootscholten advises doctors to thoroughly inform patients in advance about the pros and cons of both treatments. Based on his/her own situation every patient can make a well-considered choice for one of the two treatments.

Grootscholten treated two groups of patients for two years with either drips containing cyclophosphamide (treatment 1) or a combination of drips containing prednisone and oral azathioprine (treatment 2). After 2 years all of the patients were further treated with a low dose of oral prednisone and azathioprine.

Kidney function

The majority of patients faired better than the researchers had expected at the start of the study in 1995. Grootscholten observed that the chance of the disease recurring in the kidneys was greater in the group of patients treated with treatment 2. Shingles also occurred more frequently in this group. However, Grootscholten could not demonstrate a difference between treatment 1 and treatment 2 in terms of long-term kidney function. Moreover in the end, just as many people needed dialysis.

Quality of life

Treatment 1 was experienced as heavier than treatment 2. Yet there were no differences in terms of quality of life or complaints. Treatment 1 is known to increase the risk of infertility and early menopause. Therefore treatment 2 remains as an alternative. A more extensive study is needed for more concrete statements.

Lupus nephritis

Lupus nephritis is a severe kidney inflammation caused by the autoimmune disease systemic lupus erythematodes. The body produces antibodies against its own organs and treatment is absolutely necessary. The condition is rare. Each year 6 in every 100,000 people in the Netherlands develop the disease. Up until 40 years ago patients died from lupus nephritis. Since then various treatment methods have been sought to suppress the inflammation in the kidney. To date no thorough research into the differences between these methods had been carried out.

Dr Cecile Grootscholten | alfa
Further information:
http://www.nwo.nl/nwohome.nsf/pages/NWOA_6ZYL6T_Eng

More articles from Health and Medicine:

nachricht NIST scientists discover how to switch liver cancer cell growth from 2-D to 3-D structures
17.11.2017 | National Institute of Standards and Technology (NIST)

nachricht High speed video recording precisely measures blood cell velocity
15.11.2017 | ITMO University

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: A “cosmic snake” reveals the structure of remote galaxies

The formation of stars in distant galaxies is still largely unexplored. For the first time, astron-omers at the University of Geneva have now been able to closely observe a star system six billion light-years away. In doing so, they are confirming earlier simulations made by the University of Zurich. One special effect is made possible by the multiple reflections of images that run through the cosmos like a snake.

Today, astronomers have a pretty accurate idea of how stars were formed in the recent cosmic past. But do these laws also apply to older galaxies? For around a...

Im Focus: Visual intelligence is not the same as IQ

Just because someone is smart and well-motivated doesn't mean he or she can learn the visual skills needed to excel at tasks like matching fingerprints, interpreting medical X-rays, keeping track of aircraft on radar displays or forensic face matching.

That is the implication of a new study which shows for the first time that there is a broad range of differences in people's visual ability and that these...

Im Focus: Novel Nano-CT device creates high-resolution 3D-X-rays of tiny velvet worm legs

Computer Tomography (CT) is a standard procedure in hospitals, but so far, the technology has not been suitable for imaging extremely small objects. In PNAS, a team from the Technical University of Munich (TUM) describes a Nano-CT device that creates three-dimensional x-ray images at resolutions up to 100 nanometers. The first test application: Together with colleagues from the University of Kassel and Helmholtz-Zentrum Geesthacht the researchers analyzed the locomotory system of a velvet worm.

During a CT analysis, the object under investigation is x-rayed and a detector measures the respective amount of radiation absorbed from various angles....

Im Focus: Researchers Develop Data Bus for Quantum Computer

The quantum world is fragile; error correction codes are needed to protect the information stored in a quantum object from the deteriorating effects of noise. Quantum physicists in Innsbruck have developed a protocol to pass quantum information between differently encoded building blocks of a future quantum computer, such as processors and memories. Scientists may use this protocol in the future to build a data bus for quantum computers. The researchers have published their work in the journal Nature Communications.

Future quantum computers will be able to solve problems where conventional computers fail today. We are still far away from any large-scale implementation,...

Im Focus: Wrinkles give heat a jolt in pillared graphene

Rice University researchers test 3-D carbon nanostructures' thermal transport abilities

Pillared graphene would transfer heat better if the theoretical material had a few asymmetric junctions that caused wrinkles, according to Rice University...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Ecology Across Borders: International conference brings together 1,500 ecologists

15.11.2017 | Event News

Road into laboratory: Users discuss biaxial fatigue-testing for car and truck wheel

15.11.2017 | Event News

#Berlin5GWeek: The right network for Industry 4.0

30.10.2017 | Event News

 
Latest News

NASA detects solar flare pulses at Sun and Earth

17.11.2017 | Physics and Astronomy

NIST scientists discover how to switch liver cancer cell growth from 2-D to 3-D structures

17.11.2017 | Health and Medicine

The importance of biodiversity in forests could increase due to climate change

17.11.2017 | Studies and Analyses

VideoLinks
B2B-VideoLinks
More VideoLinks >>>