Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:


Rush Researchers Participate in Worldwide AIDS Initiative Led by Imperial College London

Researchers at Rush University Medical Center have been selected to participate in a collaborative initiative to develop a simple, affordable and rapid test to measure the immune systems of people infected with HIV/AIDS in developing countries. The four year CD4 Initiative is conducted under the leadership of Imperial College London with funding from the Bill & Melinda Gates Foundation.

The CD4 Initiative will develop an easy to use device that can measure CD4+ T-lymphocytes in HIV+ patients. The CD4 cell count measures the number of these critical disease-fighting cells in the blood, a figure that health care workers need in order to make key clinical decisions in managing HIV disease, such as when to begin or to switch antiretroviral therapy.

Study co-investigator Alan Landay, PhD, chairman of the department of Immunology and Microbiology at Rush, said current technologies for measuring CD4 counts are expensive to buy and maintain, and require a level of infrastructure and training that is often not available in many developing countries.

“In remote villages where there are likely to be no laboratory facilities, health care workers need a simple point-of-care test they can perform with little training,” said Landay. “The goal is an inexpensive test that can use blood from a simple finger prick and requires no sample processing or microscopy.”

Landay will collaborate with scientists at the Burnet Institute in Melbourne, Australia. The technology underpinning this test was developed by associate professor David Anderson, a co-investigator on this grant and deputy director at the Burnet Institute. The principal investigator on the proposal is Suzanne Crowe, head of the Pathogenesis and Clinical Research Program at the Burnet Institute. Other co-investigators include Professor Tom Denny of Duke University School of Medicine.

The initiative will take a project management approach using multiple research teams around the world from academia, private companies and other institutions that will work collaboratively under the leadership of Imperial College London.

“Despite the burden of HIV/AIDS on the developing worlds, many of the diagnostic tools are just not accessible there due to the high cost and complexity of use. This initiative will help develop new, simple, rapid, robust and affordable tools and help remove one important barrier to the effective implementation of AIDS care in these countries,” said professor Stephen Smith, principal of the faculty of medicine at Imperial College London.

Initial funding for the proof of concept was provided by a grant from the Doris Duke Foundation.

Kim Waterman | EurekAlert!
Further information:

More articles from Health and Medicine:

nachricht Advanced analysis of brain structure shape may track progression to Alzheimer's disease
26.10.2016 | Massachusetts General Hospital

nachricht Indian roadside refuse fires produce toxic rainbow
26.10.2016 | Duke University

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Etching Microstructures with Lasers

Ultrafast lasers have introduced new possibilities in engraving ultrafine structures, and scientists are now also investigating how to use them to etch microstructures into thin glass. There are possible applications in analytics (lab on a chip) and especially in electronics and the consumer sector, where great interest has been shown.

This new method was born of a surprising phenomenon: irradiating glass in a particular way with an ultrafast laser has the effect of making the glass up to a...

Im Focus: Light-driven atomic rotations excite magnetic waves

Terahertz excitation of selected crystal vibrations leads to an effective magnetic field that drives coherent spin motion

Controlling functional properties by light is one of the grand goals in modern condensed matter physics and materials science. A new study now demonstrates how...

Im Focus: New 3-D wiring technique brings scalable quantum computers closer to reality

Researchers from the Institute for Quantum Computing (IQC) at the University of Waterloo led the development of a new extensible wiring technique capable of controlling superconducting quantum bits, representing a significant step towards to the realization of a scalable quantum computer.

"The quantum socket is a wiring method that uses three-dimensional wires based on spring-loaded pins to address individual qubits," said Jeremy Béjanin, a PhD...

Im Focus: Scientists develop a semiconductor nanocomposite material that moves in response to light

In a paper in Scientific Reports, a research team at Worcester Polytechnic Institute describes a novel light-activated phenomenon that could become the basis for applications as diverse as microscopic robotic grippers and more efficient solar cells.

A research team at Worcester Polytechnic Institute (WPI) has developed a revolutionary, light-activated semiconductor nanocomposite material that can be used...

Im Focus: Diamonds aren't forever: Sandia, Harvard team create first quantum computer bridge

By forcefully embedding two silicon atoms in a diamond matrix, Sandia researchers have demonstrated for the first time on a single chip all the components needed to create a quantum bridge to link quantum computers together.

"People have already built small quantum computers," says Sandia researcher Ryan Camacho. "Maybe the first useful one won't be a single giant quantum computer...

All Focus news of the innovation-report >>>



Event News

#IC2S2: When Social Science meets Computer Science - GESIS will host the IC2S2 conference 2017

14.10.2016 | Event News

Agricultural Trade Developments and Potentials in Central Asia and the South Caucasus

14.10.2016 | Event News

World Health Summit – Day Three: A Call to Action

12.10.2016 | Event News

Latest News

3-D-printed magnets

26.10.2016 | Power and Electrical Engineering

Advanced analysis of brain structure shape may track progression to Alzheimer's disease

26.10.2016 | Health and Medicine

3-D-printed structures shrink when heated

26.10.2016 | Materials Sciences

More VideoLinks >>>