Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Rush Researchers Participate in Worldwide AIDS Initiative Led by Imperial College London

04.04.2007
Researchers at Rush University Medical Center have been selected to participate in a collaborative initiative to develop a simple, affordable and rapid test to measure the immune systems of people infected with HIV/AIDS in developing countries. The four year CD4 Initiative is conducted under the leadership of Imperial College London with funding from the Bill & Melinda Gates Foundation.

The CD4 Initiative will develop an easy to use device that can measure CD4+ T-lymphocytes in HIV+ patients. The CD4 cell count measures the number of these critical disease-fighting cells in the blood, a figure that health care workers need in order to make key clinical decisions in managing HIV disease, such as when to begin or to switch antiretroviral therapy.

Study co-investigator Alan Landay, PhD, chairman of the department of Immunology and Microbiology at Rush, said current technologies for measuring CD4 counts are expensive to buy and maintain, and require a level of infrastructure and training that is often not available in many developing countries.

“In remote villages where there are likely to be no laboratory facilities, health care workers need a simple point-of-care test they can perform with little training,” said Landay. “The goal is an inexpensive test that can use blood from a simple finger prick and requires no sample processing or microscopy.”

Landay will collaborate with scientists at the Burnet Institute in Melbourne, Australia. The technology underpinning this test was developed by associate professor David Anderson, a co-investigator on this grant and deputy director at the Burnet Institute. The principal investigator on the proposal is Suzanne Crowe, head of the Pathogenesis and Clinical Research Program at the Burnet Institute. Other co-investigators include Professor Tom Denny of Duke University School of Medicine.

The initiative will take a project management approach using multiple research teams around the world from academia, private companies and other institutions that will work collaboratively under the leadership of Imperial College London.

“Despite the burden of HIV/AIDS on the developing worlds, many of the diagnostic tools are just not accessible there due to the high cost and complexity of use. This initiative will help develop new, simple, rapid, robust and affordable tools and help remove one important barrier to the effective implementation of AIDS care in these countries,” said professor Stephen Smith, principal of the faculty of medicine at Imperial College London.

Initial funding for the proof of concept was provided by a grant from the Doris Duke Foundation.

Kim Waterman | EurekAlert!
Further information:
http://www.rush.edu

More articles from Health and Medicine:

nachricht Correct connections are crucial
26.06.2017 | Charité - Universitätsmedizin Berlin

nachricht One gene closer to regenerative therapy for muscular disorders
01.06.2017 | Cincinnati Children's Hospital Medical Center

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Can we see monkeys from space? Emerging technologies to map biodiversity

An international team of scientists has proposed a new multi-disciplinary approach in which an array of new technologies will allow us to map biodiversity and the risks that wildlife is facing at the scale of whole landscapes. The findings are published in Nature Ecology and Evolution. This international research is led by the Kunming Institute of Zoology from China, University of East Anglia, University of Leicester and the Leibniz Institute for Zoo and Wildlife Research.

Using a combination of satellite and ground data, the team proposes that it is now possible to map biodiversity with an accuracy that has not been previously...

Im Focus: Climate satellite: Tracking methane with robust laser technology

Heatwaves in the Arctic, longer periods of vegetation in Europe, severe floods in West Africa – starting in 2021, scientists want to explore the emissions of the greenhouse gas methane with the German-French satellite MERLIN. This is made possible by a new robust laser system of the Fraunhofer Institute for Laser Technology ILT in Aachen, which achieves unprecedented measurement accuracy.

Methane is primarily the result of the decomposition of organic matter. The gas has a 25 times greater warming potential than carbon dioxide, but is not as...

Im Focus: How protons move through a fuel cell

Hydrogen is regarded as the energy source of the future: It is produced with solar power and can be used to generate heat and electricity in fuel cells. Empa researchers have now succeeded in decoding the movement of hydrogen ions in crystals – a key step towards more efficient energy conversion in the hydrogen industry of tomorrow.

As charge carriers, electrons and ions play the leading role in electrochemical energy storage devices and converters such as batteries and fuel cells. Proton...

Im Focus: A unique data centre for cosmological simulations

Scientists from the Excellence Cluster Universe at the Ludwig-Maximilians-Universität Munich have establised "Cosmowebportal", a unique data centre for cosmological simulations located at the Leibniz Supercomputing Centre (LRZ) of the Bavarian Academy of Sciences. The complete results of a series of large hydrodynamical cosmological simulations are available, with data volumes typically exceeding several hundred terabytes. Scientists worldwide can interactively explore these complex simulations via a web interface and directly access the results.

With current telescopes, scientists can observe our Universe’s galaxies and galaxy clusters and their distribution along an invisible cosmic web. From the...

Im Focus: Scientists develop molecular thermometer for contactless measurement using infrared light

Temperature measurements possible even on the smallest scale / Molecular ruby for use in material sciences, biology, and medicine

Chemists at Johannes Gutenberg University Mainz (JGU) in cooperation with researchers of the German Federal Institute for Materials Research and Testing (BAM)...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Plants are networkers

19.06.2017 | Event News

Digital Survival Training for Executives

13.06.2017 | Event News

Global Learning Council Summit 2017

13.06.2017 | Event News

 
Latest News

New 3-D model predicts best planting practices for farmers

26.06.2017 | Agricultural and Forestry Science

New research reveals impact of seismic surveys on zooplankton

26.06.2017 | Life Sciences

Correct connections are crucial

26.06.2017 | Health and Medicine

VideoLinks
B2B-VideoLinks
More VideoLinks >>>