Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Development of a diagnostic chip to test for multiple sexually transmitted infections

13.12.2006
Oxford Gene Technology in collaboration with St George’s, University of London and St George’s Healthcare NHS Trust to develop diagnostic chip to test for multiple sexually transmitted infections

Oxford Gene Technology (OGT), St George’s University of London and St George’s Healthcare NHS Trust are pleased to announce the signing of a collaboration agreement to develop a cost-effective single platform microarray to diagnose multiple sexually transmitted infections (STIs).

The collaboration between OGT and St George’s aims to develop a diagnostic test with the capacity to detect the DNA of many sexually transmitted pathogens in one specimen from infected people.

The microarray test aims for more comprehensive and accurate diagnoses with accurate same-day results. Ultimately, the array technology lends itself to the development of point-of-care testing for multiple STIs combined with the highest standards of accuracy. The STI diagnostic microarray is a timely investment in new gene technologies that directly address the emerging crisis of STIs in the UK, highlighted by the recent report of the Health Protection Agency (2006).

Dr Tariq Sadiq, Senior Lecturer and Consultant Genito Urinary Physician at St George’s, said on behalf of the University and NHS Trust “The incidence of STI continues to rise and is challenging our ability to provide care for our patients, directly costing the NHS in excess of £1 billion a year. As more responsibility for this care falls on settings such as GP practices, community based sexual health care providers and even high street pharmacies, concern exists for the need to maintain high standards of diagnostic accuracy while also recognising the increasing role of many infections not traditionally tested for. If successful, we think the microarray may be an important tool in the attempts to reduce the burden of STIs and their transmission”

Diagnostic DNA microarrays or ‘gene chips’ have been pioneered by the research team of Professor Philip Butcher, of St George’s, University of London, for bacterial and viral pathogen detection, exploiting expertise in bacterial microarrays built up by the Wellcome Trust funded B?G@S project (http://www.bugs.sgul.ac.uk).

In partnership with St George’s clinical and microbiology expertise, OGT will design and develop the high quality optimised 60mer oligonucleotide microarray using its ink jet in-situ synthesis (IJISS) platform and will also investigate the use of its Multi Sample Array (MSA) format enabling the parallel analysis of multiple samples. This will aim to reduce the cost per sample and provide a rapid diagnostic result.

Dr John Anson, Research and Development Director at OGT said: “OGT’s microarray technologies will provide a nucleic acid based tool which, coupled with PCR amplification, is aimed at producing a diagnostic test to improve the detection range, accuracy and the speed of STI diagnosis to meet clinician’s needs.”

The project will be jointly funded by the Heptagon Proof of Concept Fund and OGT and will last a year in the first instance. By then end of this period, the team hope to have a prototype which will then be validated using clinical samples.

To access a copy of the HPA report, “A complex picture: HIV & other sexually transmitted infections in the United Kingdom: 2006” http://www.hpa.org.uk/publications/2006/hiv_sti_2006/default.htm

For further information, please contact:

At Oxford Gene Technology:
Nicola Booton-Mander, Marketing Manager
Oxford Gene Technology
Begbroke Science Park,
Sandy Lane, Yarnton
Oxford OX5 1PF
T: +44 1865 856352
F: +44 1865 842116
E: services@ogt.co.uk
W: www.ogt.co.uk
Media Enquiries:
Annabel Entress, 0203 008 7557 / a.entress@northbankcommunications.com
Sarah Jeffery, 0203 008 7557 / s.jeffery@northbankcommunications.com
At St George’s, University of London:
Eve Jaques
Technology Transfer Officer
Centre for Enterprise and Innovation,
Hunter Wing,
Cranmer Terrace
London, SW17 0RE
Tel: +44 (0)20 8266 6865
Fax: +44 (0)20 8725 0312
Email: ejaques@sgul.ac.uk
Website: www.enterprise.sgul.ac.uk
Media Enquiries:
Andrea Vazquez, 020 8725 1139, avazquez@sgul.ac.uk

Andrea Vazquez | alfa
Further information:
http://www.sgul.ac.uk
http://www.ogt.co.uk
http://www.enterprise.sgul.ac.uk

More articles from Health and Medicine:

nachricht Researchers release the brakes on the immune system
18.10.2017 | Rheinische Friedrich-Wilhelms-Universität Bonn

nachricht Norovirus evades immune system by hiding out in rare gut cells
12.10.2017 | University of Pennsylvania School of Medicine

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Neutron star merger directly observed for the first time

University of Maryland researchers contribute to historic detection of gravitational waves and light created by event

On August 17, 2017, at 12:41:04 UTC, scientists made the first direct observation of a merger between two neutron stars--the dense, collapsed cores that remain...

Im Focus: Breaking: the first light from two neutron stars merging

Seven new papers describe the first-ever detection of light from a gravitational wave source. The event, caused by two neutron stars colliding and merging together, was dubbed GW170817 because it sent ripples through space-time that reached Earth on 2017 August 17. Around the world, hundreds of excited astronomers mobilized quickly and were able to observe the event using numerous telescopes, providing a wealth of new data.

Previous detections of gravitational waves have all involved the merger of two black holes, a feat that won the 2017 Nobel Prize in Physics earlier this month....

Im Focus: Smart sensors for efficient processes

Material defects in end products can quickly result in failures in many areas of industry, and have a massive impact on the safe use of their products. This is why, in the field of quality assurance, intelligent, nondestructive sensor systems play a key role. They allow testing components and parts in a rapid and cost-efficient manner without destroying the actual product or changing its surface. Experts from the Fraunhofer IZFP in Saarbrücken will be presenting two exhibits at the Blechexpo in Stuttgart from 7–10 November 2017 that allow fast, reliable, and automated characterization of materials and detection of defects (Hall 5, Booth 5306).

When quality testing uses time-consuming destructive test methods, it can result in enormous costs due to damaging or destroying the products. And given that...

Im Focus: Cold molecules on collision course

Using a new cooling technique MPQ scientists succeed at observing collisions in a dense beam of cold and slow dipolar molecules.

How do chemical reactions proceed at extremely low temperatures? The answer requires the investigation of molecular samples that are cold, dense, and slow at...

Im Focus: Shrinking the proton again!

Scientists from the Max Planck Institute of Quantum Optics, using high precision laser spectroscopy of atomic hydrogen, confirm the surprisingly small value of the proton radius determined from muonic hydrogen.

It was one of the breakthroughs of the year 2010: Laser spectroscopy of muonic hydrogen resulted in a value for the proton charge radius that was significantly...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

ASEAN Member States discuss the future role of renewable energy

17.10.2017 | Event News

World Health Summit 2017: International experts set the course for the future of Global Health

10.10.2017 | Event News

Climate Engineering Conference 2017 Opens in Berlin

10.10.2017 | Event News

 
Latest News

Terahertz spectroscopy goes nano

20.10.2017 | Information Technology

Strange but true: Turning a material upside down can sometimes make it softer

20.10.2017 | Materials Sciences

NRL clarifies valley polarization for electronic and optoelectronic technologies

20.10.2017 | Interdisciplinary Research

VideoLinks
B2B-VideoLinks
More VideoLinks >>>