Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Development of a diagnostic chip to test for multiple sexually transmitted infections

13.12.2006
Oxford Gene Technology in collaboration with St George’s, University of London and St George’s Healthcare NHS Trust to develop diagnostic chip to test for multiple sexually transmitted infections

Oxford Gene Technology (OGT), St George’s University of London and St George’s Healthcare NHS Trust are pleased to announce the signing of a collaboration agreement to develop a cost-effective single platform microarray to diagnose multiple sexually transmitted infections (STIs).

The collaboration between OGT and St George’s aims to develop a diagnostic test with the capacity to detect the DNA of many sexually transmitted pathogens in one specimen from infected people.

The microarray test aims for more comprehensive and accurate diagnoses with accurate same-day results. Ultimately, the array technology lends itself to the development of point-of-care testing for multiple STIs combined with the highest standards of accuracy. The STI diagnostic microarray is a timely investment in new gene technologies that directly address the emerging crisis of STIs in the UK, highlighted by the recent report of the Health Protection Agency (2006).

Dr Tariq Sadiq, Senior Lecturer and Consultant Genito Urinary Physician at St George’s, said on behalf of the University and NHS Trust “The incidence of STI continues to rise and is challenging our ability to provide care for our patients, directly costing the NHS in excess of £1 billion a year. As more responsibility for this care falls on settings such as GP practices, community based sexual health care providers and even high street pharmacies, concern exists for the need to maintain high standards of diagnostic accuracy while also recognising the increasing role of many infections not traditionally tested for. If successful, we think the microarray may be an important tool in the attempts to reduce the burden of STIs and their transmission”

Diagnostic DNA microarrays or ‘gene chips’ have been pioneered by the research team of Professor Philip Butcher, of St George’s, University of London, for bacterial and viral pathogen detection, exploiting expertise in bacterial microarrays built up by the Wellcome Trust funded B?G@S project (http://www.bugs.sgul.ac.uk).

In partnership with St George’s clinical and microbiology expertise, OGT will design and develop the high quality optimised 60mer oligonucleotide microarray using its ink jet in-situ synthesis (IJISS) platform and will also investigate the use of its Multi Sample Array (MSA) format enabling the parallel analysis of multiple samples. This will aim to reduce the cost per sample and provide a rapid diagnostic result.

Dr John Anson, Research and Development Director at OGT said: “OGT’s microarray technologies will provide a nucleic acid based tool which, coupled with PCR amplification, is aimed at producing a diagnostic test to improve the detection range, accuracy and the speed of STI diagnosis to meet clinician’s needs.”

The project will be jointly funded by the Heptagon Proof of Concept Fund and OGT and will last a year in the first instance. By then end of this period, the team hope to have a prototype which will then be validated using clinical samples.

To access a copy of the HPA report, “A complex picture: HIV & other sexually transmitted infections in the United Kingdom: 2006” http://www.hpa.org.uk/publications/2006/hiv_sti_2006/default.htm

For further information, please contact:

At Oxford Gene Technology:
Nicola Booton-Mander, Marketing Manager
Oxford Gene Technology
Begbroke Science Park,
Sandy Lane, Yarnton
Oxford OX5 1PF
T: +44 1865 856352
F: +44 1865 842116
E: services@ogt.co.uk
W: www.ogt.co.uk
Media Enquiries:
Annabel Entress, 0203 008 7557 / a.entress@northbankcommunications.com
Sarah Jeffery, 0203 008 7557 / s.jeffery@northbankcommunications.com
At St George’s, University of London:
Eve Jaques
Technology Transfer Officer
Centre for Enterprise and Innovation,
Hunter Wing,
Cranmer Terrace
London, SW17 0RE
Tel: +44 (0)20 8266 6865
Fax: +44 (0)20 8725 0312
Email: ejaques@sgul.ac.uk
Website: www.enterprise.sgul.ac.uk
Media Enquiries:
Andrea Vazquez, 020 8725 1139, avazquez@sgul.ac.uk

Andrea Vazquez | alfa
Further information:
http://www.sgul.ac.uk
http://www.ogt.co.uk
http://www.enterprise.sgul.ac.uk

More articles from Health and Medicine:

nachricht 3D images of cancer cells in the body: Medical physicists from Halle present new method
16.05.2018 | Martin-Luther-Universität Halle-Wittenberg

nachricht Better equipped in the fight against lung cancer
16.05.2018 | Friedrich-Alexander-Universität Erlangen-Nürnberg

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Explanation for puzzling quantum oscillations has been found

So-called quantum many-body scars allow quantum systems to stay out of equilibrium much longer, explaining experiment | Study published in Nature Physics

Recently, researchers from Harvard and MIT succeeded in trapping a record 53 atoms and individually controlling their quantum state, realizing what is called a...

Im Focus: Dozens of binaries from Milky Way's globular clusters could be detectable by LISA

Next-generation gravitational wave detector in space will complement LIGO on Earth

The historic first detection of gravitational waves from colliding black holes far outside our galaxy opened a new window to understanding the universe. A...

Im Focus: Entangled atoms shine in unison

A team led by Austrian experimental physicist Rainer Blatt has succeeded in characterizing the quantum entanglement of two spatially separated atoms by observing their light emission. This fundamental demonstration could lead to the development of highly sensitive optical gradiometers for the precise measurement of the gravitational field or the earth's magnetic field.

The age of quantum technology has long been heralded. Decades of research into the quantum world have led to the development of methods that make it possible...

Im Focus: Computer-Designed Customized Regenerative Heart Valves

Cardiovascular tissue engineering aims to treat heart disease with prostheses that grow and regenerate. Now, researchers from the University of Zurich, the Technical University Eindhoven and the Charité Berlin have successfully implanted regenerative heart valves, designed with the aid of computer simulations, into sheep for the first time.

Producing living tissue or organs based on human cells is one of the main research fields in regenerative medicine. Tissue engineering, which involves growing...

Im Focus: Light-induced superconductivity under high pressure

A team of scientists of the Max Planck Institute for the Structure and Dynamics of Matter (MPSD) at the Center for Free-Electron Laser Science in Hamburg investigated optically-induced superconductivity in the alkali-doped fulleride K3C60under high external pressures. This study allowed, on one hand, to uniquely assess the nature of the transient state as a superconducting phase. In addition, it unveiled the possibility to induce superconductivity in K3C60 at temperatures far above the -170 degrees Celsius hypothesized previously, and rather all the way to room temperature. The paper by Cantaluppi et al has been published in Nature Physics.

Unlike ordinary metals, superconductors have the unique capability of transporting electrical currents without any loss. Nowadays, their technological...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

Save the date: Forum European Neuroscience – 07-11 July 2018 in Berlin, Germany

02.05.2018 | Event News

Invitation to the upcoming "Current Topics in Bioinformatics: Big Data in Genomics and Medicine"

13.04.2018 | Event News

Unique scope of UV LED technologies and applications presented in Berlin: ICULTA-2018

12.04.2018 | Event News

 
Latest News

Supersonic waves may help electronics beat the heat

18.05.2018 | Power and Electrical Engineering

Keeping a Close Eye on Ice Loss

18.05.2018 | Information Technology

CrowdWater: An App for Flood Research

18.05.2018 | Information Technology

VideoLinks
Science & Research
Overview of more VideoLinks >>>